scholarly journals Study on alignment test based on ASTM E1012 and Chinese guideline

ACTA IMEKO ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 159
Author(s):  
Xiaobing Zhao ◽  
Wansheng Li ◽  
Minghui Fei ◽  
Xiaolan Zheng ◽  
William Huang
Keyword(s):  
Axial Force ◽  
Strain Gauge ◽  
Testing Machine ◽  
Test Results ◽  
Standard Practice ◽  
Force Application ◽  
Comparison Test ◽  
First Time ◽  
Compressive Axial Force

This paper describes the study about alignment test on testing machine. It is based on the standards of ASTM E1012-14 (Standard Practice for Verification of Testing Frame and Specimen Alignment Under Tensile and Compressive Axial Force Application) and Chinese calibration guideline. The strain-gauge specimens of ASTM and reference extensometer of Chinese guideline were both tested on one testing machine. The test results were analyzed and compared. The traceability about both methods were also discussed. Meanwhile the amplifier was calibrated before test. It is the first time in China to performance this comparison test.

scholarly journals COT-13 Current situation and problems of cancer genomic profiling test in Kyoto University Hospital

2020 ◽  
Vol 2 (Supplement_3) ◽  
pp. ii22-ii22
Author(s):  
Yoshiki Arakawa ◽  
Junko Suga ◽  
Yukinori Terada ◽  
Kohei Nakajima ◽  
Masahiro Tanji ◽  
...  
Keyword(s):  
Treatment Options ◽  
Insurance Coverage ◽  
Germline Mutations ◽  
University Hospital ◽  
Genomic Profiling ◽  
Test Results ◽  
Final Test ◽  
First Time ◽  
To Receive ◽  
Secondary Finding

Abstract Objective: Kyoto University Hospital has introduced the cancer genomic profiling tests, Oncoprime in 2015, Guardant360 in 2018, which are not under insurance coverage, FoundationOne CDx(F1CDx) and OncoGuide NCC Oncopanel system(NCC OP) in 2019, which received approval for insurance coverage for the first time in Japan. We investigated the results of cancer genomic profiling test under insurance coverage in our hospital. Methods: A special facility for the cancer genomic profiling tests was produced. To perform the cancer genomic profiling test, an outpatient must visit the facility three times (learning, ordering of the test, and getting the results). The expert panels decide the final test results and treatment options with the all information of the patients. Results: From November 2019 to March 2020, 51 and 9 patients were tested with F1CDx and NCC OP, respectively. 16 patients (31%) of F1CDX and 2 patients (22%) of NCC OP got treatment recommendations from the expert panels. However, only 5 patients (9.8%) of F1CDX and 1 patient (11%) of NCC OP received the treatments. The secondary finding suspecting germline mutations was found in 8 patients of F1CDX. Conclusion: After the approval the cancer genomic profiling tests with insurance coverage in Japan, it becomes easy for the patients to perform the test and get the genetic information of the tumor. However, it remains not easy to receive the recommended drugs because of several limitations of their usages.

Improving the Strength of Abrasive Wheels and Optimizing the Control over the Strength of Composite Abrasive Materials

2019 ◽  
Vol 946 ◽  
pp. 380-385
Author(s):  
Boris A. Chaplygin ◽  
Viacheslav V. Shirokov ◽  
Tat'yana A. Lisovskaya ◽  
Roman A. Lisovskiy
Keyword(s):  
Mechanical Properties ◽  
Test Results ◽  
Key Factors ◽  
Special Equipment ◽  
Material Density ◽  
Factors Affecting ◽  
Control Factors ◽  
Reinforcing Material ◽  
Special Studies ◽  
First Time

The strength of abrasive wheels is one of the key factors affecting the performance of abrasive machining. The paper discusses ways to improve the strength of abrasive wheels. The stress-state mathematical model presented herein is a generalization of the existing models. It is used herein to find for the first time that there are numerous optimal combinations of the elastic modulus and reinforcing material density, which result in the same minimum value of the objective function. It is found out that increasing the radius of the reinforcing component while also optimizing the mechanical properties of its material may increase the permissible breaking speed of the wheel several times. We herein present a regression equation and a nomogram for finding the optimal combination of control factors. Conventional methods for testing the mechanical properties of materials, which have been proven reliable for testing metals and alloys, are not as reliable for testing abrasive materials, as the test results they generate are not sufficiently stable or accurate. We therefore propose an alternative method that does not require any special equipment or special studies.

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