Cigarette smoking as a risk factor for acute respiratory distress syndrome: a systematic review and meta-analysis

2017 ◽  
Vol 1 ◽  
pp. 3-3 ◽  
Author(s):  
Zhongheng Zhang
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Acute Respiratory Distress Syndrome ◽  
Cigarette Smoking ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Meta Analysis

scholarly journals Cigarette smoking as a risk factor for acute respiratory distress syndrome: a systematic review and meta-analysis

2014 ◽  
Author(s):  
Zhongheng Zhang
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Acute Respiratory Distress Syndrome ◽  
General Population ◽  
Cigarette Smoking ◽  
Lung Injury ◽  
Respiratory Distress Syndrome ◽  
Distress Syndrome ◽  
Meta Analysis ◽  
Major Surgery

Background and objectives: Numerous experimental studies have linked cigarette smoking to lung injury. However, it is still debated on whether cigarette smoking is a risk factor for the development of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The study aimed to solve the controversy by performing systematic review and meta-analysis. Methods: Electronic databases including Pubmed, Google scholar, Embase and Scopus were searched from inception to April 2014. Studies investigated the association of cigarette smoking and ALI/ARDS were included. Non-randomized studies were assessment for their methodological quality by using Newcastle-Ottawa scale. Meta-analysis was performed by using random effects model and subgroup analyses were performed to address the clinical heterogeneity. Publication bias was assessed by using Egger’s test. Main result: Of the 17 studies included in our analysis, 15 provided data on effect size and were meta-analyzable. Component studies involved heterogeneous populations including major surgery, trauma, septic shock, general population, influenza A infection and transfusion. The combined results showed that cigarette smoking was not a risk factor for the development of ALI/ARDS (OR: 1.00, 95% CI: 0.99-1.01). In subgroup analysis, the same result was obtained in general population (OR: 2.03, 95% CI: 0.06-4.01), patients with major surgery or trauma (OR: 1.20, 95% CI: 0.48-1.93) and patients with other risks of ALI/ARDS (OR: 1.00, 95% CI: 0.99-1.01). Conclusion: Our study demonstrates that cigarette smoking is not associated with increased risk of ALI/ARDS in critically ill patients. However, the relationship in general population is still controversial and requires further confirmation.

scholarly journals Cigarette smoking as a risk factor for acute respiratory distress syndrome: a systematic review and meta-analysis

2014 ◽  
Author(s):  
Zhongheng Zhang
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Acute Respiratory Distress Syndrome ◽  
General Population ◽  
Cigarette Smoking ◽  
Lung Injury ◽  
Respiratory Distress Syndrome ◽  
Distress Syndrome ◽  
Meta Analysis ◽  
Major Surgery

Background and objectives: Numerous experimental studies have linked cigarette smoking to lung injury. However, it is still debated on whether cigarette smoking is a risk factor for the development of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The study aimed to solve the controversy by performing systematic review and meta-analysis. Methods: Electronic databases including Pubmed, Google scholar, Embase and Scopus were searched from inception to April 2014. Studies investigated the association of cigarette smoking and ALI/ARDS were included. Non-randomized studies were assessment for their methodological quality by using Newcastle-Ottawa scale. Meta-analysis was performed by using random effects model and subgroup analyses were performed to address the clinical heterogeneity. Publication bias was assessed by using Egger’s test. Main result: Of the 17 studies included in our analysis, 15 provided data on effect size and were meta-analyzable. Component studies involved heterogeneous populations including major surgery, trauma, septic shock, general population, influenza A infection and transfusion. The combined results showed that cigarette smoking was not a risk factor for the development of ALI/ARDS (OR: 1.00, 95% CI: 0.99-1.01). In subgroup analysis, the same result was obtained in general population (OR: 2.03, 95% CI: 0.06-4.01), patients with major surgery or trauma (OR: 1.20, 95% CI: 0.48-1.93) and patients with other risks of ALI/ARDS (OR: 1.00, 95% CI: 0.99-1.01). Conclusion: Our study demonstrates that cigarette smoking is not associated with increased risk of ALI/ARDS in critically ill patients. However, the relationship in general population is still controversial and requires further confirmation.

scholarly journals Incidence and Mortality of Acute Respiratory Distress Syndrome in Patients With Burns: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Baoli Wang ◽  
Wei Chenru ◽  
Yong Jiang ◽  
Lunyang Hu ◽  
He Fang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mechanical Ventilation ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Meta Analysis ◽  
Inhalation Injury ◽  
African Countries ◽  
Incidence And Mortality

Objective: We conducted a systematic review and meta-analysis to comprehensively estimate the incidence and mortality of acute respiratory distress syndrome (ARDS) in overall and subgroups of patients with burns.Data sources: Pubmed, Embase, the Cochrane Library, CINAHL databases, and China National Knowledge Infrastructure database were searched until September 1, 2021.Study selection: Articles that report study data on incidence or mortality of ARDS in patients with burns were selected.Data extraction: Two researchers independently screened the literature, extracted data, and assessed the quality. We performed a meta-analysis of the incidence and mortality of ARDS in patients with burns using a random effects model, which made subgroup analysis according to the study type, inclusion (mechanical ventilation, minimal burn surface), definitions of ARDS, geographic location, mean age, burn severity, and inhalation injury. Primary outcomes were the incidence and mortality of burns patients with ARDS, and secondary outcomes were incidence for different subgroups.Data synthesis: Pooled weighted estimate of the incidence and mortality of ARDS in patients with burns was 0.24 [95% confidence interval (CI)0.2–0.28] and 0.31 [95% CI 0.18−0.44]. Incidences of ARDS were obviously higher in patients on mechanical ventilation (incidence = 0.37), diagnosed by Berlin definition (incidence = 0.35), and with over 50% inhalation injury proportion (incidence = 0.41) than in overall patients with burns. Patients with burns who came from western countries and with inhalation injury have a significantly higher incidence of ARDS compared with those who came from Asian/African countries (0.28 vs. 0.25) and without inhalation injury (0.41 vs. 0.24).Conclusion: This systematic review and meta-analysis revealed that the incidence of ARDS in patients with burns is 24% and that mortality is as high as 31%. The incidence rates are related to mechanical ventilation, location, and inhalation injury. The patients with burns from western countries and with inhalation injury have a significantly higher incidence than patients from Asian/African countries and without inhalation injury.Systematic Review Registration: identifier: CRD42021144888.

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