scholarly journals Comparison of the Masaoka-Koga staging and the International Association for the Study of Lung Cancer/the International Thymic Malignancies Interest Group proposal for the TNM staging systems based on the Chinese Alliance for Research in Thymomas retrospective database

2016 ◽  
Vol 8 (4) ◽  
pp. 727-737 ◽  
Author(s):  
Guanghui Liang ◽  
◽  
Zhitao Gu ◽  
Yin Li ◽  
Jianhua Fu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Interest Group ◽  
International Association ◽  
Tnm Staging ◽  
Staging Systems ◽  
Retrospective Database

scholarly journals Eighth Edition Staging of Thoracic Malignancies: Implications for the Reporting Pathologist

2018 ◽  
Vol 142 (5) ◽  
pp. 645-661 ◽  
Author(s):  
Andrew G. Nicholson ◽  
Ming S. Tsao ◽  
William D. Travis ◽  
Deepa T. Patil ◽  
Francoise Galateau-Salle ◽  
...  
Keyword(s):  
Interest Group ◽  
International Association ◽  
External Validation ◽  
Cancer Control ◽  
Tnm Staging ◽  
Classification Systems ◽  
Thymic Epithelial Tumors ◽  
American Joint Committee ◽  
Thoracic Malignancies ◽  
8Th Edition

Context The Staging and Prognostic Factors Committee of the International Association for the Study of Lung Cancer, in conjunction with the International Mesothelioma Interest Group, the International Thymic Malignancy Interest Group, and the Worldwide Esophageal Cancer Collaboration, developed proposals for the 8th edition of their respective tumor, node, metastasis (TNM) staging classification systems. Objective To review these changes and discuss issues for the reporting pathologist. Data Sources Proposals were based on international databases of lung (N = 94 708), with an external validation using the US National Cancer Database; mesothelioma (N = 3519); thymic epithelial tumors (10 808); and epithelial cancers of the esophagus and esophagogastric junction (N = 22 654). Conclusions These proposals have been mostly accepted by the Union for International Cancer Control and the American Joint Committee on Cancer and incorporated into their respective staging manuals (2017). The Union for International Cancer Control recommended implementation beginning in January 2017; however, the American Joint Committee on Cancer has deferred deployment of the eighth TNM until January 1, 2018, to ensure appropriate infrastructure for data collection. This manuscript summarizes the updated staging of thoracic malignancies, specifically highlighting changes from the 7th edition that are relevant to pathologic staging. Histopathologists should become familiar with, and start to incorporate, the 8th edition staging in their daily reporting of thoracic cancers henceforth.

Lung Carcinoma Staging Update

2016 ◽  
Vol 141 (7) ◽  
pp. 923-926 ◽  
Author(s):  
Sanja Dacic
Keyword(s):  
Lung Cancer ◽  
Lung Carcinoma ◽  
Survival Data ◽  
International Association ◽  
Cancer Staging ◽  
Tnm Staging ◽  
Tnm System ◽  
Pathologic Staging ◽  
Prognostic Stratification ◽  
Cancer Outcome

Context.— The International Association for the Study of Lung Cancer Staging Committee has prospectively created an international lung cancer database that was used to address many lung cancer staging questions, such as tumor size, nodal status, and metastatic disease. The proposed changes for the upcoming 8th edition of the cancer staging manual were based on survival data and better prognostic stratification of patients with lung cancer. Objectives.— To review published recommendations for the revision of lung carcinoma TNM staging and to address potential challenges in pathologic staging. Data Source.— PubMed available articles by the International Association for the Study of Lung Cancer Staging Committee were reviewed. Conclusions.— The TNM system remains the best prognosticator of lung cancer outcome. The recommendations are established on new prospective data analysis and reflect the improvements in prognostic separation of patients with lung cancer based on a multidisciplinary approach.

scholarly journals Evaluation of the new TNM staging system proposed by the International Association for the Study of Lung Cancer at a single institution

2009 ◽  
Vol 137 (5) ◽  
pp. 1180-1184 ◽  
Author(s):  
Kotaro Kameyama ◽  
Mamoru Takahashi ◽  
Keiji Ohata ◽  
Hitoshi Igai ◽  
Akihiko Yamashina ◽  
...  
Keyword(s):  
Lung Cancer ◽  
International Association ◽  
Staging System ◽  
Tnm Staging ◽  
Single Institution ◽  
Tnm Staging System

scholarly journals Future Perspectives on the TNM Staging for Lung Cancer

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1940
Author(s):  
Ramón Rami-Porta
Keyword(s):  
Lung Cancer ◽  
International Association ◽  
Tnm Classification ◽  
Distant Metastases ◽  
Tnm Staging ◽  
Related Factors ◽  
The North ◽  
Factor Data ◽  
Protein Alterations ◽  
The Impact

Since its conception by Pierre Denoix in the mid-20th century, the tumor, node, and metastasis (TNM) classification has undergone seven revisions. The North American database managed by Clifton Mountain was used to inform the 2nd to the 6th editions, and an international database collected by the International Association for the Study of Lung Cancer, promoted by Peter Goldstraw, was used to inform the 7th and the 8th editions. In these two latest editions, it was evident that the impact of tumor size was much greater than it was suggested in previous editions; that the amount of nodal disease had prognostic relevance; and that the number and location of the distant metastases had prognostic implications. However, the TNM classification is not the only prognostic factor. Data are being collected now to inform the 9th edition of the TNM classification, scheduled for publication in 2024. Patient-, environment-, and tumor-related factors, including biomarkers (genetic biomarkers, copy number alterations, and protein alterations) are being collected to combine them in prognostic groups to enhance the prognosis provided by the mere anatomic extent of the tumor, and to offer a more personalized prognosis to an individual patient. International collaboration is essential to build a large and detailed database to achieve these objectives.

scholarly journals Evaluation of the 7th and 8th editions of the AJCC/UICC TNM staging systems for lung cancer in a large North American cohort

Oncotarget ◽  
2017 ◽  
Vol 8 (40) ◽  
pp. 66784-66795 ◽  
Author(s):  
Lin Yang ◽  
Shidan Wang ◽  
Yunyun Zhou ◽  
Sunny Lai ◽  
Guanghua Xiao ◽  
...  
Keyword(s):  
Lung Cancer ◽  
North American ◽  
Tnm Staging ◽  
Staging Systems ◽  
North American Cohort
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