scholarly journals Projection of Down's syndrome births in the United States 1979-2000, and the potential effects of prenatal diagnosis.

1983 ◽  
Vol 73 (10) ◽  
pp. 1186-1189 ◽  
Author(s):  
C A Huether
1975 ◽  
Vol 14 (12) ◽  
pp. 1150-1154 ◽  
Author(s):  
Hiroshi Shiono ◽  
Junichi Kadowaki ◽  
Takeki Fujiwara ◽  
Tooru Nakao

Hepatitis-Associated (Australia) Antigen (HAA) was detected in 13 (5.8%) of 223 patients with Down's syndrome and in 14 (3.7%) of 378 patients with other forms of mental retardation. The frequency of HAA was 2.4 per cent in 127 noninstitutionalized patients with Down's syndrome, and 10.4 per cent in 96 institutionalized patients. The frequency of HAA with Down's syndrome was lower on the average in Japan than in the United States or Germany. HAA was detected in one (1.3%) of 78 mothers of infants with Down's syndrome. Our study suggests that maternal exposure to HAA, as reflected by the presence of either HAA or anti-HAA, was not associated with the subsequent birth of an infant with Down's syndrome.


2002 ◽  
Vol 42 (3) ◽  
pp. 258-260 ◽  
Author(s):  
Mitsuo Sakaihara

Wrongful birth claim is generally defined as a claim by the parents of a child born alive but with a disability that a doctor was negligent in permitting the pregnancy to continue to birth. There have been four cases relating to congenital rubella syndrome and one case relating to Down's syndrome held in Japan. The claims brought by the mothers were that, but for the negligence of the doctor in managing the pregnancy, the mother would have had a lawful abortion and the child would not have been born to suffer a disability. As we do not have the provision of foetal indication for abortion in Japan, wrongful birth claim by parents is founded upon a breach of doctors' duty in advising of the probability of a disabled child. We compare the lawful nature of wrongful birth claims in Japan with those in the United States and the United Kingdom.


1990 ◽  
Vol 85 (3) ◽  
pp. 362-366 ◽  
Author(s):  
Tomas Porstmann ◽  
Roselotte Wietschke ◽  
Günther Cobet ◽  
Katja Lorenz ◽  
Roland Grunow ◽  
...  

1992 ◽  
Vol 2 (6) ◽  
pp. 446-447 ◽  
Author(s):  
A. Salamanca ◽  
A. Girona ◽  
M. C. Padilla ◽  
R. M. Sabatel ◽  
F. Gonzales-Gomez

PEDIATRICS ◽  
1978 ◽  
Vol 62 (1) ◽  
pp. 52-53
Author(s):  
Richard H. Heller ◽  
Lee S. Palmer

Both the detection of twins and the successful execution of a double amniocentesis pose significant technical problems in prenatal diagnosis. A case is reported in which one of twin fetuses had trisomy 21 and the other was chromosomally normal. Following counseling, the family chose to continue the pregnancy. At term, the mother was delivered of a healthy infant and a severely macerated fetus with stigmata suggestive of Down's syndrome.


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