Determination of Phosphate in Human Serum with Zirconium/Reduced Graphene Oxide Modified Electrode

Poly(methylene blue) and electrochemically reduced graphene oxide composite film modified electrode (PMB-ERGO/GCE) was successfully fabricated by electropolymerization and was used for simultaneous determination of uric acid (UA) and xanthine (Xa). Based on the excellent electrocatalytic activity of PMB-ERGO/GCE, the electrochemical behaviors of UA and Xa were studied by cyclic voltammetry (CV) and square wave voltammetry (SWV). Two anodic sensitive peaks at 0.630 V (versus Ag/AgCl) for UA and 1.006 V (versus Ag/AgCl) for Xa were given by CV in pH 3.0 phosphate buffer. The calibration curves for UA and Xa were obtained in the range of 8.00 × 10−8~4.00 × 10−4 M and 1.00 × 10−7~4.00 × 10−4 M, respectively, by SWV. The detection limits for UA and Xa were3.00×10-8 M and5.00×10-8 M, respectively. Finally, the proposed method was applied to simultaneously determine UA and Xa in human urine with good selectivity and high sensitivity.

Download Full-text

Sensitive electrochemical determination of epinephrine at poly(L-aspartic acid)/electro-chemically reduced graphene oxide modified electrode by square wave voltammetry in pharmaceutics

Journal of Electroanalytical Chemistry ◽

10.1016/j.jelechem.2017.11.045 ◽

2017 ◽

Vol 807 ◽

pp. 145-153 ◽

Cited By ~ 19

Author(s):

Birhanu Mekassa ◽

Merid Tessema ◽

Bhagwan Singh Chandravanshi ◽

Priscilla G.L. Baker ◽

Francis N. Muya

Keyword(s):

Graphene Oxide ◽

Reduced Graphene Oxide ◽

Aspartic Acid ◽

Modified Electrode ◽

Square Wave Voltammetry ◽

Electrochemical Determination ◽

Wave Voltammetry ◽

Reduced Graphene ◽

Chemically Reduced Graphene Oxide

Download Full-text

Determination of Tocopherol Using Reduced Graphene Oxide-Nafion Hybrid-Modified Electrode in Pharmaceutical Capsules and Vegetable Oil Samples

Food Analytical Methods ◽

10.1007/s12161-015-0353-x ◽

2015 ◽

Vol 9 (6) ◽

pp. 1745-1753 ◽

Cited By ~ 2

Author(s):

Hayati Filik ◽

Asiye Aslıhan Avan ◽

Sevda Aydar ◽

Şeyda Çakar

Keyword(s):

Graphene Oxide ◽

Reduced Graphene Oxide ◽

Modified Electrode ◽

Vegetable Oil ◽

Reduced Graphene

Download Full-text

An Electrochemically Reduced Copper/Reduced Graphene Oxide Film Modified Electrode for Sensitive Non-Enzymatic Glucose Detection in Human Serum

10.21203/rs.3.rs-264254/v1 ◽

2021 ◽

Author(s):

Sopit Phetsang ◽

Pinit Kidkhunthod ◽

Narong Chanlek ◽

Jaroon Jakmunee ◽

Pitchaya Mungkornasawakul ◽

...

Keyword(s):

Graphene Oxide ◽

Human Serum ◽

Reduced Graphene Oxide ◽

Modified Electrode ◽

Electrocatalytic Activity ◽

Glucose Sensor ◽

Electrochemical Sensors ◽

High Sensitivity ◽

Detection Range ◽

Reduced Graphene

Abstract Numerous studies suggest that modification with functional nanomaterials can enhance the electrode electrocatalytic activity, sensitivity, and selectivity of the electrochemical sensors. Here, a highly sensitive and cost-effective disposable non-enzymatic glucose sensor based on copper(II)/reduced graphene oxide modified screen-printed carbon electrode is demonstrated. Facile fabrication of the developed sensing electrodes is carried out by the adsorption of copper(II) onto graphene oxide modified electrode, then following the electrochemical reduction. The proposed sensor illustrates good electrocatalytic activity toward glucose oxidation with a wide linear detection range from 0.10 mM to 12.5 mM, low detection limit of 65 µM, and high sensitivity of 172 µA mM− 1 cm− 2 along with satisfactory anti-interference ability, reproducibility, stability, and the acceptable recoveries for the detection of glucose in a human serum sample (95.6–106.4%). The copper(II)/reduced graphene oxide based sensor with the superior performances is a great potential for the quantitation of glucose in real samples.

Download Full-text