scholarly journals High-level persistence of biofilm formation in in methicillin resistant Staphylococcus aureus

Author(s):  
Chavadi, M. ◽  
Narasanna, R. ◽  
Manjula, R. ◽  
Kelmani, C. R.
2008 ◽  
Vol 13 (14) ◽  
pp. 1-2
Author(s):  
Angela Rossney ◽  
S O'Connell

High-level mupirocin resistance was detected among 37 of 2,586 (1.4%) methicillin-resistant Staphylococcus aureus (MRSA) blood-stream isolates sent to the Ireland's National MRSA Reference Laboratory between 1 January 1999 and 31 December 2005, compared with 29 of 997 isolates (2.9%) sent between 1 January 2006 and 31 December 2007.


RSC Advances ◽  
2017 ◽  
Vol 7 (38) ◽  
pp. 23392-23406 ◽  
Author(s):  
Sivasamy Sethupathy ◽  
Loganathan Vigneshwari ◽  
Alaguvel Valliammai ◽  
Krishnaswamy Balamurugan ◽  
Shunmugiah Karutha Pandian

In the present study, the antibiofilm, antipathogenic and anticarotenogenic potential ofl-ascorbyl 2,6-dipalmitate (ADP) against methicillin-resistantStaphylococcus aureus(MRSA) has been evaluated.


2021 ◽  
Vol 30 (1) ◽  
pp. 109-114
Author(s):  
Nancy M. Attia ◽  
Abeer Abd El Rahim Ghazal ◽  
Omnia M. Khaleel ◽  
Ahmed Gaballah

Background: Methicillin-resistant Staphylococcus aureus (MRSA) colonization is considered a major risk factor for nosocomial infections and its decolonization has reduced these infections. Mupirocin (MUP) is the topical antibiotic of choice for decolonization. MUP decolonization failure is attributed to MUP resistance. Objective: The aim of the current study is to assess MUP resistance among MRSA isolates phenotypically and genotypically. Methodology: Fifty MRSA isolates were identified in Microbiology Department in the Medical Research Institute hospital, Alexandria University. Antibiotic susceptibility to different classes of antibiotics by disk diffusion method was done. MUP minimum inhibitory concentration (MIC) was determined phenotypically by MUP Ezy MIC™ Strips. MUP resistance was determined genetically by multiplex PCR detection of mupA and mupB. Results: Of all MRSA isolates, 6% exhibited high level and none showed low level MUP resistance. Only mupA was detected in all resistant isolates. Conclusion: Despite low prevalence of MUP resistance, it is appropriate to test MUP resistance prior nasal decolonization


2020 ◽  
Vol 261 ◽  
pp. 113167
Author(s):  
Fernanda de Oliveira Galvão ◽  
Fabiana Gomes da Silva Dantas ◽  
Carolina Rangel de Lima Santos ◽  
Silvana Beutinger Marchioro ◽  
Claudia Andrea Lima Cardoso ◽  
...  

2016 ◽  
Vol 14 (28) ◽  
pp. 6853-6856 ◽  
Author(s):  
Matthew D. Stephens ◽  
Nisakorn Yodsanit ◽  
Christian Melander

A small molecule library consisting of 45 compounds was synthesized based on the bacterial metabolite ethylN-(2-phenethyl) carbamate. From this library, a more potent, broad-spectrum inhibitor of MRSA biofilm formation was discovered.


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