The predictive value of red cell distribution width for stroke severity and outcome

Abstract Objectives: In the present study, we sought to investigate the association between red cell distribution width (RDW) and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasminogen activator (tPA). Results: In this prospective study, 282 stroke patients who underwent tPA injection were included. The categorization of RDW to <12.9% and >13% values revealed insignificant difference in stroke severity score, accounting for the mean 36-hour NIHSS of 8.19±8.2 in normal RDW values and 9.94±8.28in higher RDW group (p=0.64). In seventh day, NIHSS was 6.46±7.28 in normal RDW group and was 8.52±8.35 in increased RDW group (p=0.058). Neither the thirty-six-hour, nor the seventh day and 3-month mRS demonstrated significant difference between those with normal and higher RDW values.

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The predictive value of red cell distribution width for stroke severity and outcome

10.21203/rs.2.11222/v2 ◽

2019 ◽

Author(s):

Kavous Shahsavarinia ◽

Fatemeh Seifar ◽

Elyar Sadeghi-Hokmabadi ◽

Younes Ghavam Laleh ◽

Payman Moharramzadeh ◽

...

Keyword(s):

Thrombolytic Therapy ◽

Stroke Severity ◽

Red Cell ◽

Cell Distribution ◽

Stroke Patients ◽

Distribution Width ◽

Significant Difference ◽

Tissue Plasminogen ◽

Insignificant Difference ◽

The Mean

Abstract Objectives: In the present study, we sought to investigate the association between RDW and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasminogen activator (tPA). Results: In this prospective study, 282 stroke patients who underwent tPA injection were included. The categorization of RDW to <12.9 and >13 values revealed insignificant difference in stroke severity score, accounting for the mean 36-hour NIHSS of 8.19±8.2 in normal RDW values and 9.94±8.28in higher RDW group (p=0.64). In seventh day, NIHSS was 6.46±7.28 in normal RDW group and was 8.52±8.35 in increased RDW group (p=0.058). Neither the thirty-six-hour, nor the seventh day and 3-month MRS demonstrated significant difference between those with normal and higher RDW values.

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The predictive value of red cell distribution width for stroke severity and outcome

10.21203/rs.2.11222/v1 ◽

2019 ◽

Author(s):

Kavous Shahsavarinia ◽

Younes Ghavam Laleh ◽

Payman Moharramzadeh ◽

Mahboob Pouraghaei ◽

Elyar Sadeghi-Hokmabadi ◽

...

Keyword(s):

Emergency Department ◽

Severity Score ◽

Stroke Severity ◽

Red Cell ◽

Cell Distribution ◽

Distribution Width ◽

Significant Difference ◽

Tissue Plasminogen ◽

Insignificant Difference ◽

The Mean

Abstract Objectives: In the present study, we sought to investigate the association of RDW with stroke severity and outcomes in patients who underwent anti-thrombolytic administration with tissue plasminogen activator (tPA). Results: This study was conducted during eighteen months at emergency department. During the time of study, 282 subjects were included. The categorization of RDW to <12.9 and >13 values revealed insignificant difference in stroke severity score, accounting for the mean 36-hour NIHSS of 8.19±8.2 in normal RDW values and 9.94±8.28in higher RDW group (p=0.64). In seventh day assessment, NIHSS was 6.46±7.28 in normal RDW group and was 8.52±8.35 in increased RDW group (p=0.058). Neither the thirty-six-hour, nor the seventh day and 3-month MRS demonstrated significant difference between those with normal and higher RDW values.

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The effects of atorvastatin treatment on the mean platelet volume and red cell distribution width in patients with dyslipoproteinemia and comparison with plasma atherogenicity indicators—A pilot study

Clinical Biochemistry ◽

10.1016/j.clinbiochem.2015.02.010 ◽

2015 ◽

Vol 48 (9) ◽

pp. 557-561 ◽

Cited By ~ 18

Author(s):

Marek Kucera ◽

David Balaz ◽

Peter Kruzliak ◽

Rachele Ciccocioppo ◽

Stanislav Oravec ◽

...

Keyword(s):

Pilot Study ◽

Mean Platelet Volume ◽

Red Cell Distribution Width ◽

Red Cell ◽

Cell Distribution ◽

Platelet Volume ◽

Distribution Width ◽

Atorvastatin Treatment ◽

The Mean

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Relation between Red Cell Distribution Width and Left Ventricular Function in Children with Heart Failure

ISRN Pediatrics ◽

10.1155/2014/234835 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 6

Author(s):

Wegdan Mawlana ◽

Amr Donia ◽

Doaa Elamrousy

Keyword(s):

Heart Failure ◽

Left Ventricular Function ◽

Ventricular Function ◽

Left Ventricular ◽

Red Cell Distribution Width ◽

University Hospital ◽

Red Cell ◽

Cell Distribution ◽

Distribution Width ◽

The Mean

Background. Most of the studies done on adults showed that red cell distribution width (RDW) can be used as a prognostic marker in patients with chronic heart failure. However, RDW has not been tested in children with heart failure. Methods and Results. 31 children with heart failure admitted to Cardiology Unit, Tanta University Hospital, during the period of January 2012 to December 2012 were included in this study, RDW as a component of routine blood count was evaluated and correlated to the echocardiographic parameters of left ventricle. The mean age of our cohort was 16.16 ± 14.97 months, congenital heart disease with left-to-right shunt represented 58.1% of the underlying causes of heart failure while dilated cardiomyopathy made 41.9%. The mean hemoglobin level was 9.14 ± 1.18 gm/dL; RDW level ranged from 10.7% to 27.7% with a mean of 16.01 ± 3.34. Hemoglobin was significantly correlated with RDW at any level. For the echo parameters, at cutoff point of 16.4%, RDW was significantly correlated with fraction shortening (FS), and A, E/A ratio, but it was not correlated with LVEDD, LVESD, and E/É at the same cutoff level. Conclusion. RDW, a simple, available test, can be used as a marker for the left ventricular function in children with heart failure until an echocardiography assessment for the patients is done.

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The predictive value of red cell distribution width for stroke severity and outcome

BMC Research Notes ◽

10.1186/s13104-020-05125-y ◽

2020 ◽

Vol 13 (1) ◽

Author(s):

Kavous Shahsavarinia ◽

Younes Ghavam Laleh ◽

Payman Moharramzadeh ◽

Mahboob Pouraghaei ◽

Elyar Sadeghi-Hokmabadi ◽

...

Keyword(s):

Predictive Value ◽

Red Cell Distribution Width ◽

Stroke Severity ◽

Red Cell ◽

Cell Distribution ◽

Distribution Width

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Red cell distribution width and neurological scoring systems in acute stroke patients

Neuropsychiatric Disease and Treatment ◽

10.2147/ndt.s81525 ◽

2015 ◽

pp. 733 ◽

Cited By ~ 17

Author(s):

Hasan Kara ◽

Selim Degirmenci ◽

Aysegul Bayir ◽

Ahmet Ak ◽

Murat Akinci ◽

...

Keyword(s):

Acute Stroke ◽

Scoring Systems ◽

Red Cell Distribution Width ◽

Red Cell ◽

Cell Distribution ◽

Stroke Patients ◽

Distribution Width

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Relationship between red cell distribution width and prognosis of patients with osteosarcoma

Bioscience Reports ◽

10.1042/bsr20192590 ◽

2019 ◽

Vol 39 (12) ◽

Cited By ~ 2

Author(s):

Jian Zheng ◽

Xiaopin Yuan ◽

Weichun Guo

Keyword(s):

Poor Prognosis ◽

Survival Curve ◽

Poor Response ◽

Red Cell Distribution Width ◽

Red Cell ◽

Cell Distribution ◽

Poor Overall Survival ◽

Distribution Width ◽

Significant Difference

Abstract We retrospectively collected the clinical data and follow-up information of patients with osteosarcoma who were admitted to Department of Orthopedics, RenMin Hospital of Wuhan University from January 2010 to December 2016 and explore the relationship between red cell distribution width (RDW) and prognosis of patients with osteosarcoma. The present study finally included 271 patients with osteosarcoma with median follow-up time of 24.2 months (3–69 months). According to the RDW median, 135 patients belong to the low RDW group and 136 patients belong to high RDW group. Compared with low RDW group, the high RDW group tend to have metastasis (50 vs 32.6%, P=0.004), higher poor response rate to chemotherapy compared with the low RDW group (24.3 vs 7.4%, P=0.000) and higher C-reactive protein (CRP) (7.6 ± 4.9 vs 5.5 ± 4.5, t = 3.727, P=0.000). There was slightly significant difference in the types of pathology (χ2 = 8.059, P=0.045). The Kaplan–Meier analysis indicated survival curve of high RDW group was poorer than that in the low RDW group (P=0.020). The univariate cox analysis indicated that patients with RDW ≥ median had higher risk of poor prognosis compared with those who had RDW level < median (HR = 2.41, 95% confidence interval (CI): 1.51–3.83, P=0.000). After adjusting some potential cofounding factors, the elevated RDW was still associated with poor prognosis (HR = 1.66, 95% CI: 1.07–2.56, P=0.024). The elevated pretreatment RDW was associated with poor overall survival (OS) in patients with osteosarcoma and can be an independent predictor of prognosis.

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Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients

Annals of Geriatric Medicine and Research ◽

10.4235/agmr.20.0042 ◽

2020 ◽

Vol 24 (3) ◽

pp. 211-217

Author(s):

Eduard Zalyesov ◽

Inna Shugaev ◽

Yanna Prokopov ◽

Ron Shahory ◽

Stefan Chirmicci ◽

...

Keyword(s):

Functional Outcome ◽

Red Cell Distribution Width ◽

Red Cell ◽

Cell Distribution ◽

Stroke Patients ◽

Distribution Width

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Association of the mean platelet volume and red cell distribution width with dipper and non-dipper blood pressure in prehypertensive non-smokers

BMC Research Notes ◽

10.1186/s13104-019-4868-x ◽

2019 ◽

Vol 12 (1) ◽

Cited By ~ 1

Author(s):

Mohammadreza Taban Sadeghi ◽

Zahra Soroureddin ◽

Masoud Nouri-Vaskeh ◽

Pantea Nazarpoori ◽

Saeideh Aghayari Sheikh Neshin

Keyword(s):

Blood Pressure ◽

Mean Platelet Volume ◽

Red Cell Distribution Width ◽

Bivariate Analysis ◽

Red Cell ◽

Cell Distribution ◽

Platelet Volume ◽

Distribution Width ◽

Cardiovascular Damage ◽

The Mean

Abstract Objective Absence of nocturnal blood pressure (BP) dipping is associated with poor health outcomes, including increased mortality. Non-dipper BP seems to be a predictor of cardiovascular damage in hypertensive patients. The aim of this study was to investigate the association of the mean platelet volume (MPV) and red cell distribution width (RDW) with nocturnal dipping/non dipping status in newly diagnosed and untreated prehypertensive non-smokers, using ambulatory BP monitoring. Results Twenty-eight patients (15 males) in the dipper group and 24 patients (11 males) in the non-dipper group were evaluated in this study. The age of patients was 41.64 ± 15.01 and 37.96 ± 15.08 years in the dipper and non-dipper groups, respectively. The rate of nocturnal systolic BP drop in the dipper and non-dipper groups was 13.79 ± 3.35% (10.20–22.10) and 5.96 ± 2.87% (1.10–9.30) (P < 0.001), respectively. Also, the mean rate of nocturnal diastolic BP drop in the dipper and non-dipper groups was 17.02 ± 5.09% (10.30–26.90) and 6.19 ± 2.75% (1.20–9.70) (P < 0.001), respectively. RDW and MPV were significantly higher in non-dipper patients than dipper patients (P = 0.001 and P = 0.012, respectively). Bivariate analysis revealed that MPV was inversely correlated with the nocturnal systolic BP drop (P = 0.005, r = − 0.385). Furthermore, RDW was inversely correlated with systolic BP drop (P = 0.019, r = − 0.324).

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