scholarly journals Age is a predictor for the recurrence of syncope in vasovagal syncope patients with a positive head-up tilt test

2019 ◽  
Author(s):  
Yongjuan Guo ◽  
Xiaomin Chen ◽  
Tianze Zeng ◽  
Lin Wang ◽  
Lvwei Cen
Keyword(s):  
Confidence Interval ◽  
Vasovagal Syncope ◽  
Predictive Performance ◽  
Tilt Test ◽  
Logistics Regression ◽  
Increased Risk ◽  
Significant Difference ◽  
Valid Predictor ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Abstract BACKROUND Valid predictors of the recurrence of syncope in vasovagal syncope (VVS) patients with a positive head-up tilt test (HUTT) are currently lacking. The goal of this study was to identify the predictive performance of age for the recurrence of syncope in VVS patients with a positive HUTT. METHODS in total, 175 VVS patients with a positive HUTT were followed for 6 to 32 months, and ≥1 syncope episodes during follow-up was considered the recurrence of syncope. The study population was divided into 2 groups, namely, a recurrence of syncope group (44 patients) and a no recurrence of syncope group (131 patients). The baseline clinical data, hemodynamic parameters and classification of the vasovagal syncope on the HUTT were analyzed. Binary logistics regression was used to analyze the effect size and confidence interval of age. A receiver operating characteristic(ROC) analysis was used to assess the predictive performance and investigate the predictive value of age by the area under the curve (AUC). RESULTS The age of recurrence of syncope group 60.0 (47.8, 66.0) years was older than that of no recurrence of syncope group 53.0 (43.0, 62.0) years, and there was a significant difference between the two groups (P < 0.05). The trend of syncope recurrence changed with age and the binary logistics regression model adjusted by sex showed that the elder was an increased risk of syncope recurrence in VVS with positive HUTT [OR value: 1.034, 95% confidence interval(CI) 1.008 to 1.061 p < 0.05].Age was a valid predictor for the recurrence of syncope in VVS patients with a positive HUTT (AUC: 0.688; 95%CI 0.598 to 0.777 p < 0.05) . The cut-off value was 53.5 years, and the sensitivity and specificity were 72.7% and 52.7%, respectively. CONCLUSIONS Age was a valid predictor for recurrence of syncope in VVS patients with positive HUTT. The rate of recurrence of syncope increased with increasing age, especially in old female.

scholarly journals Age is a predictor for the recurrence of syncope in vasovagal syncope patients with a positive head-up tilt test

2019 ◽  
Author(s):  
Yongjuan Guo ◽  
Xiaomin Chen ◽  
Tianze Zeng ◽  
Lin Wang ◽  
Lvwei Cen
Keyword(s):  
Confidence Interval ◽  
Vasovagal Syncope ◽  
Predictive Performance ◽  
Tilt Test ◽  
Logistics Regression ◽  
Increased Risk ◽  
Significant Difference ◽  
Valid Predictor ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Abstract BACKROUND Valid predictors of the recurrence of syncope in vasovagal syncope(VVS) patients with a positive head-up tilt test (HUTT) are currently lacking. The goal of this study was to identify the predictive performance of age for the recurrence of syncope in VVS patients with a positive HUTT.METHODS in total, 175 VVS patients with a positive HUTT were followed for 6 to 32 months, and ≥1 syncope episodes during follow-up was considered the recurrence of syncope. The study population was divided into 2 groups, namely, a recurrence of syncope group (44 patients) and a no recurrence of syncope group (131 patients). The baseline clinical data, hemodynamic parameters and classification of the vasovagal syncope on the HUTT were analyzed. Logistics regression was used to analyze the effect size and confidence interval of age. A receiver operating characteristic(ROC) analysis was used to assess the predictive performance and investigate the predictive value of age by the area under the curve (AUC).RESULTS The age of recurrence of syncope group 60.0 (47.8, 66.0) years was older than that of no recurrence of syncope group 53.0 (43.0, 62.0) years, and there was a significant difference between the two groups (P < 0.05). The trend of syncope recurrence changed with age and the logistics regression model adjusted by sex showed that the elder was an increased risk of syncope recurrence in VVS with positive HUTT [OR value: 1.03, 95% confidence interval(CI) 1.008 to 1.061 p < 0.05].Age was a valid predictor for the recurrence of syncope in VVS patients with a positive HUTT (AUC: 0.688; 95%CI 0.598 to 0.777 p < 0.05). The cut-off value was 53.5 years, and the sensitivity and specificity were 72.7% and 52.7%, respectively. CONCLUSIONS Age may be a valid predictor for recurrence of syncope in VVS patients with positive HUTT. The rate of recurrence of syncope increased with increasing age, especially in old female.

scholarly journals Age is a predictor for the recurrence of syncope in vasovagal syncope patients with a positive head-up tilt test

2019 ◽  
Author(s):  
Yongjuan Guo ◽  
Xiaomin Chen ◽  
Tianze Zeng ◽  
Lin Wang ◽  
Lvwei Cen
Keyword(s):  
Confidence Interval ◽  
Vasovagal Syncope ◽  
Predictive Performance ◽  
Tilt Test ◽  
Logistics Regression ◽  
Increased Risk ◽  
Significant Difference ◽  
Valid Predictor ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Abstract BACKROUND Valid predictors of the recurrence of syncope in vasovagal syncope (VVS) patients with a positive head-up tilt test (HUTT) are currently lacking. The goal of this study was to identify the predictive performance of age for the recurrence of syncope in VVS patients with a positive HUTT. METHODS in total, 175 VVS patients with a positive HUTT were followed for 6 to 32 months, and ≥1 syncope episodes during follow-up was considered the recurrence of syncope. The study population was divided into 2 groups, namely, a recurrence of syncope group (44 patients) and a no recurrence of syncope group (131 patients). The baseline clinical data, hemodynamic parameters and classification of the vasovagal syncope on the HUTT were analyzed. Binary logistics regression was used to analyze the effect size and confidence interval of age. A receiver operating characteristic(ROC) analysis was used to assess the predictive performance and investigate the predictive value of age by the area under the curve (AUC). RESULTS The age of recurrence of syncope group 60.0 (47.8, 66.0) years was older than that of no recurrence of syncope group 53.0 (43.0, 62.0) years, and there was a significant difference between the two groups (P < 0.05). The trend of syncope recurrence changed with age and the binary logistics regression model adjusted by sex showed that the elder was an increased risk of syncope recurrence in VVS with positive HUTT [OR value: 1.034, 95% confidence interval(CI) 1.008 to 1.061 p < 0.05].Age was a valid predictor for the recurrence of syncope in VVS patients with a positive HUTT (AUC: 0.688; 95%CI 0.598 to 0.777 p < 0.05) . The cut-off value was 53.5 years, and the sensitivity and specificity were 72.7% and 52.7%, respectively. CONCLUSIONS Age was a valid predictor for recurrence of syncope in VVS patients with positive HUTT. The rate of recurrence of syncope increased with increasing age, especially in old female.

scholarly journals Age Is a Predictor for the Syncope Recurrence in Elderly Vasovagal Syncope Patients With a Positive Head-Up Tilt Test

2021 ◽  
Vol 8 ◽  
Author(s):  
Yongjuan Guo ◽  
Xiaomin Chen ◽  
Tianze Zeng ◽  
Lin Wang ◽  
Lvwei Cen
Keyword(s):  
Logistic Regression ◽  
Confidence Interval ◽  
Vasovagal Syncope ◽  
Predictive Performance ◽  
Tilt Test ◽  
Significant Difference ◽  
Valid Predictor ◽  
Head Up Tilt ◽  
Head Up Tilt Test ◽  
Recurrence Group

Background: Valid predictors of the syncope recurrence in vasovagal syncope (VVS) patients with a positive head-up tilt test (HUTT) are currently lacking. The goal of this study was to identify the predictive performance of age for the recurrence of syncope in VVS patients with a positive HUTT.Methods: In total, 175 VVS patients with a positive HUTT were observed for 6–32 months, and the recurrence of ≥1 syncope or typical pre-syncope prodromal episodes during follow-up was considered syncope recurrence. The population was divided into 2 groups, namely, a syncope recurrence group (44 patients) and a no syncope recurrence group (131 patients). The baseline clinical data, haemodynamic parameters, and classification of VVS on the HUTT were analyzed. Logistic regression was used to analyse the effect size and confidence interval for age. A receiver operating characteristic (ROC) curve analysis was used to assess the predictive performance and investigate the predictive value of age by the area under the curve (AUC).Results: The median age of the syncope recurrence group was older than that of the no syncope recurrence group [60.0 (47.8, 66.0) years&gt;53.0 (43.0, 62.0) years], and there was a significant difference between the two groups (P &lt; 0.05). The trend for syncope recurrence changed with advancing age, and the logistic regression model adjusted by sex showed that older patients had an increased risk of syncope recurrence in VVS with a positive HUTT [OR value: 1.03, 95% confidence interval (CI): 1.008–1.061, p &lt; 0.05]. Age was a valid predictor for the recurrence of syncope in elderly VVS patients with a positive HUTT (AUC: 0.688; 95% CI: 0.598–0.777, p &lt; 0.05). The cut-off value was 53.5 years, and the sensitivity and specificity were 72.7 and 52.7%, respectively.Conclusions: Age may be a valid predictor for syncope recurrence in elderly VVS patients with a positive HUTT. The rate of syncope recurrence increased with advancing age, especially in females.

Tilt angles and positive response of head-up tilt test in children with orthostatic intolerance

2013 ◽  
Vol 25 (1) ◽  
pp. 76-80 ◽  
Author(s):  
Jing Lin ◽  
Yuli Wang ◽  
Todd Ochs ◽  
Chaoshu Tang ◽  
Junbao Du ◽  
...  
Keyword(s):  
Tilt Angle ◽  
Positive Response ◽  
Orthostatic Intolerance ◽  
Vasovagal Syncope ◽  
Tilt Test ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Appearance Time ◽  
Significant Difference ◽  
Head Up Tilt ◽  
Head Up Tilt Test

AbstractThis study aimed at examining three tilt angle-based positive responses and the time to positive response in a head-up tilt test for children with orthostatic intolerance, and the psychological fear experienced at the three angles during head-up tilt test. A total of 174 children, including 76 boys and 98 girls, aged from 4 to 18 years old (mean 11.3±2.8 years old), with unexplained syncope, were randomly divided into three groups, to undergo head-up tilt test at the angles of 60°, 70° and 80°, respectively. The diagnostic rates and times were analysed, and Wong–Baker face pain rating scale was used to access the children’s psychological fear. There were no significant differences in diagnostic rates of postural orthostatic tachycardia syndrome and vasovagal syncope at different tilt angles during the head-up tilt test (p>0.05). There was a significant difference, however, in the psychological fear at different tilt angles utilising the Kruskal–Wallis test (χ2=36.398, p<0.01). It was mildest at tilt angle 60° utilising the Kolmogorov–Smirnov test (p<0.01). A positive rank correlation was found between the psychological fear and the degree of tilt angle (rs=0.445, p<0.01). Positive response appearance time was 15.1±14.0 minutes at 60° for vasovagal syncope children. There was no significant difference in the time to positive response, at different tilt angles during the head-up tilt test for vasovagal syncope or for postural orthostatic tachycardia syndrome. Hence, it is suggested that a tilt angle of 60° and head-up tilt test time of 45 minutes should be suitable for children with vasovagal syncope.

Enhanced plasma catecholamine and cAMP response during the head-up tilt test in patients with vasovagal syncope

2005 ◽  
Vol 117 (9-10) ◽  
pp. 353-358 ◽  
Author(s):  
Peter Mitro ◽  
Emilia Rybárová ◽  
Eva Žemberová ◽  
Ivan Tkáč
Keyword(s):  
Vasovagal Syncope ◽  
Tilt Test ◽  
Plasma Catecholamine ◽  
Head Up Tilt ◽  
Head Up Tilt Test

scholarly journals Clinical Features, Prodrome Types and Vasovagal Syncope Types in Passive and Nitrate Potentiated Head Up Tilt Test

2013 ◽  
Vol 62 (18) ◽  
pp. C48-C49
Author(s):  
Lale Dinç Asarcıklı ◽  
Habibe Kafes ◽  
Yesim Guray ◽  
Umit Guray ◽  
Esra Gucuk İpek ◽  
...  
Keyword(s):  
Clinical Features ◽  
Vasovagal Syncope ◽  
Tilt Test ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Vasovagal Syncope: Diagnostic Role of Head-Up Tilt Test in Patients with Positive Ocular Compression Test

1990 ◽  
Vol 13 (11) ◽  
pp. 1416-1423 ◽  
Author(s):  
FREDRICK J. JAEGER ◽  
LORI SCHNEIDER ◽  
JAMES D. MALONEY ◽  
ROBERT P. CRUSE ◽  
FETNAT M. FOUAD-TARAZI
Keyword(s):  
Compression Test ◽  
Vasovagal Syncope ◽  
Tilt Test ◽  
Diagnostic Role ◽  
Head Up Tilt ◽  
Head Up Tilt Test

scholarly journals The Repolarization Period during the Head-Up Tilt Test in Children with Vasovagal Syncope

2020 ◽  
Vol 17 (6) ◽  
pp. 1908 ◽  
Author(s):  
Ewelina Kolarczyk ◽  
Grażyna Markiewicz-Łoskot ◽  
Lesław Szydłowski
Keyword(s):  
Vasovagal Syncope ◽  
Clinical Importance ◽  
Clinical Work ◽  
Ventricular Repolarization ◽  
Tilt Test ◽  
Wave Refraction ◽  
T Wave ◽  
Prolonged Duration ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Background: Electrocardiography (ECG) and the head-up tilt test (HUTT) are vital in clinical work-up in children with vasovagal syncope (VVS). Ventricular repolarization parameters (QT) measured during the HUTT can be indicative of electrical instability; however, these parameters are not frequently assessed. This study aimed to investigate if ventricular repolarization parameters measured during the HUTT could be indicative of future ventricular arrhythmias in children with syncope. Methods: The shape and amplitude of the T-wave and parameters of the repolarization period (QT, QTpeak, Tpeak-Tend) were evaluated in a resting ECG performed on the first day of hospitalization and in ECGs performed during three phases of the HUTT. Results: In the after-tilt phase of the HUTT, 19/30 children displayed a change in T-wave morphology. QTc was significantly longer in VVS I compared to that in VVS II patients, but not in the controls (p = 0.092). Conclusions: We need further follow-up studies to establish the clinical importance of abnormal dynamics of the repolarization period in children with VVS and negative HUTT. Therefore, children with abnormal T-wave refraction and prolonged duration of the TpTe should remain under the care of a cardiological outpatient.

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