scholarly journals Agreement between anterior segment Optical Coherence Tomography, Lenstar and Ultrasound Biomicroscopy measurements of anterior segment parameters

2019 ◽  
Author(s):  
Ziyan Yu ◽  
Ting Huang ◽  
Qiao Yu ◽  
Jun Kong ◽  
Bo Qu

Abstract Purpose To compare anterior chamber depth (ACD) and central corneal thickness (CCT) measurements by anterior segment optical coherence tomography (AS-OCT), Lenstar and ultrasound biomicroscopy (UBM). Methods A retrospective cross section study. A total of 83 eyes from 54 patients were included. Central corneal thickness (CCT) and anterior chamber depth (ACD) values obtained from three devices (AS-OCT, Lenstar and UBM) were recorded. All patients were collected from Oct. 2015 to Aug. 2016 in the Fourth Affiliated Hospital of China Medical University. Differences of these three devices (ACD and CCT) were statistically analyzed by randomized blocks analysis. Pearson correlative analysis and Bland-Altman analysis were used to compare the correlation and agreement. Results There’s no significant difference in measuring ACD by Lenstar and UBM (P>0.05), but there were significant differences in other two groups (AS-OCT and UBM, AS-OCT and Lenstar) (P<0.05). There were significant differences in the mean CCT measured by the three devices (P<0.05). There were high correlation in measuring ACD (all P<0.001, r1=0.928,r2=0.982,r3=0.932, respectively), and CCT(all P<0.001,r1=0.957,r2=0.949,r3=0.928, respectively). Conclusion AS-OCT, Lenstar and UBM yielded comparable results and are all can be used interchangeably for anterior segment measurements.

2019 ◽  
Vol 47 (12) ◽  
pp. 5950-5956 ◽  
Author(s):  
Yiyong Qian ◽  
Lin Liu ◽  
Yuehui Shi ◽  
Minli Wang ◽  
Min Li ◽  
...  

Objective To investigate the clinical indications of ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT) in eyes with inflammatory glaucoma. Methods Sixteen patients (16 eyes) with inflammatory glaucoma were analysed retrospectively. All of the subjects underwent UBM and AS-OCT scans, measuring the following parameters: central corneal thickness (CCT), central anterior chamber depth (ACD), angle-opening distance (AOD500), and trabecular-iris angle (TIA500) in four quadrants. Results Both the UBM and AS-OCT generated detailed, high-resolution images of the anterior segments of the eyes with inflammatory glaucoma. Moreover, the UBM and AS-OCT exhibited statistically similar measurement results for all of the indices. A Bland–Altman analysis showed a high level of agreement between the two imaging techniques. Additionally, the UBM was able to visualize the ciliary body and pars plana, while the cells and the flare in the anterior chamber appeared more pronounced in the UBM images. Conclusions Both the UBM and AS-OCT are useful tools for anterior segment imaging and taking measurements needed for evaluating inflammatory glaucoma. The AS-OCT has the advantages of being noninvasive and fast, whereas the UBM is presently unparalleled in the visualization of the ciliary body and pars plana.


2016 ◽  
Vol 27 (4) ◽  
pp. 417-422 ◽  
Author(s):  
José Ignacio Fernández-Vigo ◽  
Lucía De-Pablo-Gómez-De-Liaño ◽  
Cristina Fernández-Vigo ◽  
Inés Sánchez-Guillén ◽  
Enrique Santos-Bueso ◽  
...  

Purpose To determine the prevalence of trabecular-iris contact (TIC) and quantify this contact in healthy Caucasian individuals using Fourier-domain optical coherence tomography (FD-OCT). Methods For this cross-sectional study, 2,012 eyes of 1,006 healthy subjects were recruited among individuals undergoing a routine ophthalmologic checkup. In each participant, age, sex, intraocular pressure, and spherical refractive error were first recorded along with anterior chamber depth and volume, central corneal thickness measured with the Pentacam, and axial length with the IOLMaster. Anterior chamber angle variables and the presence of TIC in the horizontal quadrants were determined by anterior segment FD-OCT (RTVue 100®). When TIC was observed, TIC length (TICL) and its percentage in relation to the length of the trabecular meshwork (TICL percentage) were also measured. Results Trabecular-iris contact in the horizontal quadrants was observed in 34 eyes of 25 patients, representing 1.6% of the total number of eyes examined. In this subgroup of individuals, mean age was 55.8 years, 84% were women, and spherical refractive error ranged from -0.25 to 8.25 D. Eyes with TIC showed an angle width of less than 23.2 degrees and axial length shorter than 23.7 mm. Mean TICL was 239 ± 79 μm (103-495 μm) and mean TICL percentage was 46.9% ± 13.9% (17.2%-76.3%). Conclusions The prevalence of TIC was low in this population. Fourier-domain optical coherence tomography emerged as useful to assess its prevalence and quantify the extent of TIC.


2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Jinhai Huang ◽  
Weicong Lu ◽  
Giacomo Savini ◽  
Hao Chen ◽  
Chengfang Wang ◽  
...  

Purpose.To compare between a new optical biometer (AL-Scan, Nidek Co., Aichi, Japan) and an anterior segment optical coherence tomographer (Visante AS-OCT, Carl Zeiss Meditec, Dublin, USA) for measuring central corneal thickness (CCT), anterior chamber depth (ACD), and aqueous depth (AD).Methods.Sixty-three eyes of 63 normal subjects were examined with AL-Scan and Visante AS-OCT in this prospective study. One eye per subject was measured three times with both devices to record their CCT, ACD, and AD. All procedures were performed by the same operator. Agreement between the two devices was assessed using pairedt-tests, Bland-Altman plots, and 95% limits of agreement (LoA).Results.The mean CCT, ACD, and AD measured by AL-Scan were538.59±27.37 μm,3.70±0.30 mm, and3.16±0.30 mm, respectively. The mean values obtained by the Visante OCT were536.14±26.61 μm for CCT,3.71±0.29 mm for ACD, and3.17±0.29 mm for AD. The mean CCT by the AL-Scan was higher than that obtained by the Visante AS-OCT (difference =2.45±6.07 μm,P<0.05). The differences in ACD and AD measurements were not statistically significant. The 95% LoA of CCT, ACD, and AD were between −9.44 and 14.35 μm, −0.15 and 0.12 mm, and −0.15 and 0.12 mm, respectively.Conclusions.Since these two devices were comparable for measuring CCT, ACD, and AD, their results can be interchangeably used in the clinic.


2020 ◽  
Vol 8 (14) ◽  
pp. 857-857
Author(s):  
Xuepei Li ◽  
Yijing Zhou ◽  
Charlotte Aimee Young ◽  
Aiming Chen ◽  
Guangming Jin ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Tamer F El-Mekkawi ◽  
Hazem O Rashed ◽  
Hisham S. Saad Eldin ◽  
Hagar M Faisal

Abstract Background Chronic hyperglycemia in diabetes mellitus causes different morphologic and functional corneal changes. Aim of the Work to assess the central corneal thickness in diabetic patients with and without diabetic retinopathy using anterior segment optical coherence tomography. Patients and Methods This comparative study was conducted at Ain Shams University hospitals . It included 45 eyes divided into three groups: Group A: 15 eyes of diabetic patients without diabetic retinopathy , Group B: 15 eyes of diabetic patients with diabetic retinopathy and Group C: 15 eyes of non-diabetic individuals. Results : The mean CCT in diabetic patients without diabetic retinopathy was 551.13µ ± 37.93 with range 475-622. Diabetics with retinopathy was 558.93µ ± 39.32 with range 508-618 and non diabetics 534.73µ ± 33.67 with range 475-588. There was no significant difference in corneal thickness between the three groups (p = 0.201) Conclusion : Diabetic corneas tended to be thicker though this was not statistically significant in our work.


2007 ◽  
Vol 48 (12) ◽  
pp. 1643 ◽  
Author(s):  
Hyoung Sub Shim ◽  
Chul Young Choi ◽  
Hee Gyung Lee ◽  
Myoung Joon Kim ◽  
Hung Won Tchah

2018 ◽  
Vol 1 ◽  
pp. 3
Author(s):  
Joshua S Agranat ◽  
Yoshihiro Yonekawa

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.


Author(s):  
Alireza Khodabande ◽  
Massood Mohammadi ◽  
Hamid Riazi-Esfahani ◽  
Shahab Karami ◽  
Massood Mirghorbani ◽  
...  

Abstract Background To evaluate changes in anterior segment morphology on anterior segment optical coherence tomography (AS-OCT) following pars plana vitrectomy (PPV) without tamponade. Methods Patients who underwent PPV without tamponade for epiretinal membrane were evaluated. Eligible patients underwent intraocular pressure (IOP) measurement and AS-OCT preoperatively as well as 1 month and 6 months post-operatively. Anterior chamber width (ACW), anterior chamber depth (ACD), trabecular iris angle (TIA), angle opening distance at 500 and 750 µm (AOD), and trabecular iris space area at 500 and 750 µm (TISA) at four quadrants were recorded and analyzed. Additionally, the mean values of TIA (MTIA), AOD (MAOD), and TISA (MTISA) for each eye (mean of four quadrants) were analyzed. Results 23 patients completed the study. The mean age of participants was 56.4 ± 3.6 years of age and 13/23 (56%) were female. Mean IOP of patients was 18.1 ± 1.1, 18.3 ± 1.1, and 18.1 ± 1.2 preoperatively,1 month post-operatively, and 6 months post-operatively, respectively. (p = 0.83). No difference was detected post-operatively in measurements of ACW, ACD, MTIA, MAOD500, MAOD750, MTISA500, and MTISA750. Conclusion Pars plana vitrectomy without tamponade was not associated with changes in anterior chamber morphology.


Author(s):  
Sagili Chandrasekhara Reddy ◽  
Mohd Mansor Shariff ◽  
Aina Malindri Dasrilsyah

Purpose: To determine the central corneal thickness in myopic adult patients scheduled for laser corneal refractive surgery and to explore its correlation with degree of refractive error. Materials and Methods: The case records of 130 myopic patients who underwent laser corneal refractive surgery in a military hospital over a period of two years were reviewed to determine the central corneal thickness. All patients had 6/6 vision with best correction, and did not have any other anterior segment or fundus diseases in both eyes. The central corneal thickness was measured with Visante Carl Zeiss anterior segment optical coherence tomography instrument.                                                                                                                        Results: Out of 130 patients, males were more (73, 56.2%); mean age of patients was 33.8 years (range 18-60 years) and majority were Malays (110, 84.6%).  The spherical power of myopia ranged from – 0.5 to – 10.00 D, and the cylindrical power ranged from – 0.25 to – 3.25 D. The mean central corneal thickness of both eyes was 528.2 µm (range 331- 615 µm); in the mild degree of myopia (- 0.50 to - 2.00 D) 527.9 µm, moderate degree (- 2.25 to -5.00 D) 529.4 µm, and high degree (-5.25 to -11.00 D) 523.9 µm. Conclusion: The anterior segment optical coherence tomography provides noncontact, rapid, pachymetry mapping of the corneal thickness. In Malaysian patients, the mean central corneal thickness of both eyes in myopia was 528.1 µm (range 331- 615 µm). There was no correlation between the mean central corneal thickness and degree of myopia, different genders, age groups, ethnic groups and two eyes.


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