scholarly journals A Giant Gastrointestinal Stromal Tumor of Duodenal Origin with Spontaneous Rupture Bleeding: A Case Report

2021 ◽  
Author(s):  
Zheqi Han ◽  
Baochun Lu ◽  
Jianhua Yu ◽  
Zhiyang Zhu
Keyword(s):  
Case Report ◽  
Gastrointestinal Stromal Tumor ◽  
Blood Supply ◽  
Spontaneous Rupture ◽  
Gastrointestinal Stromal Tumors ◽  
Case Presentation ◽  
Anatomical Characteristics ◽  
Stromal Tumors ◽  
Rare Site ◽  
Duodenal Gists

Abstract BackgroundThe duodenum is a rare site of gastrointestinal stromal tumors (GISTs). The unique anatomical characteristics and rich blood supply of the duodenum make it difficult to treat duodenal GISTs in patients with bleeding.Case presentationHere we report a case of a 76-year-old female was hospitalized with a large GIST that originated in the duodenum. Imaging assessment suggested that the tumor could not be radically resected. However, the tumor was rupturing and bleeding, and therefore pancreaticoduodenectomy had to be performed. After receiving imatinib postoperatively, the patient has recovered during the 1 year after the operation.ConclusionThe results of this case suggest that pancreaticoduodenectomy may be a better choice for duodenal GISTs with rupture and bleeding.

Large Omental Metastases of a Gastrointestinal Stromal Tumor

Medicina ◽  
2011 ◽  
Vol 47 (11) ◽  
pp. 86
Author(s):  
Povilas Ignatavičius ◽  
Tomas Petraitis ◽  
Žilvinas Saladžinskas ◽  
Lilija Butkevičienė ◽  
Kristina Žvinienė
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Interstitial Cells Of Cajal ◽  
Metastatic Tumor ◽  
Stromal Tumor ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Cells Of Cajal

Gastrointestinal stromal tumors are rare tumors, originating from the interstitial cells of Cajal. They are the most common mesenchymal tumors of the gastrointestinal tract. Metastatic tumor is treated with imatinib mesylate. A case of large metastases of a gastrointestinal stromal tumor to the omentum, diagnosis and treatment principles are presented in this case report.

scholarly journals Giant gastrointestinal stromal tumor of ileum: the gist of GIST: a case report

2017 ◽  
Vol 4 (3) ◽  
pp. 1096
Author(s):  
M. S. Ray ◽  
B. S. Deepak
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Standard Of Care ◽  
Clinical Situation ◽  
Stromal Tumor ◽  
Curative Therapy ◽  
Stromal Tumors ◽  
Mesenchymal Neoplasms

Gastrointestinal stromal tumors (GIST) are relatively rare pathology as compared with other mitotic lesions of GIT. However, GIST is the most common mesenchymal neoplasms of the gastrointestinal tract. Biopsy of the lesion and Immuno-Histo-Chemistry (IHC) for CD117 confirms the diagnosis. Surgery remains the standard of care and only potentially curative therapy for patients with primary, resectable, localized gastrointestinal stromal tumor. However, chemotherapy with Imatinib is added in neoadjuvant or adjuvant form according to clinical situation, and histopathological status of the lesion.

scholarly journals Gastric gastrointestinal stromal tumor with osseous differentiation and stromal calcification: A case report and review of literature

2017 ◽  
Vol 5 ◽  
pp. 2050313X1774631 ◽  
Author(s):  
Haneen Al-Maghrabi ◽  
Abdelrazak Meliti
Keyword(s):  
Case Report ◽  
Bone Formation ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Gastric Wall ◽  
Stromal Tumor ◽  
Osseous Metaplasia ◽  
Gastrointestinal Malignancies ◽  
Stromal Tumors ◽  
Mature Bone

Gastrointestinal stromal tumors are the most common primary mesenchymal tumors of the gastrointestinal tract accounting for 0.1%–3.0% of all gastrointestinal malignancies. The stomach is the most common site (60%) followed by the small bowel (30%–35%) particularly jejunum and ileum, colorectum (5%) and rarely affect esophagus and appendix. Most gastrointestinal stromal tumors arise sporadically, however, less commonly they develop in association with various clinical syndromes like Carney triad, Carney–Stratakis syndrome, familial gastrointestinal stromal tumor syndrome and neurofibromatosis type1 (NF1). We report a 65-year-old male patient presented with gastric mass (7.5 × 4.5 × 3.5 cm) arising from the posterior gastric wall. Histologic examination revealed neoplastic proliferation of spindled and epithelioid cells with focal plexiform pattern and low mitotic activity 3/50 HPF. No evidence of cytological atypia, abnormal mitosis or necrosis. Interestingly enough, there were focal areas of mature bone formation/osseous differentiation associated with calcification. The tumor cells were strongly positive for CD117, DOG1 with focal immunoreactivity against CD34. The morphologic features and the immunoprofile were diagnostic of gastrointestinal stromal tumor. Herein, we present a rare case of gastric gastrointestinal stromal tumor with mature bone formation, osseous metaplasia and calcification. To the best of our knowledge, this is the second case report of gastric gastrointestinal stromal tumor with osseous differentiation and mature bone formation.

scholarly journals Extra-Gastrointestinal retroperitoneal giant stromal tumor complicated with intra-tumoral hemorrhage: case report and literature review

2015 ◽  
Vol 21 (1) ◽  
pp. 1-6
Author(s):  
B.A. Suciu ◽  
V. Bud ◽  
Doina Milutin ◽  
Ioana Halmaciu ◽  
C. Constantin ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Literature Review ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumor ◽  
Stromal Tumors ◽  
Pathological Characteristics ◽  
Mesenchymal Origin ◽  
Extragastrointestinal Stromal Tumor

Abstract Gastrointestinal stromal tumors are an uncommon sarcomas with mesenchymal origin that arises in the gastrointestinal tract. Recently, most of the published reports describe such tumors located outside of the gastrointestinal tract, with similar pathological characteristics and are named extra-gastrointestinal stromal tumors. We report the case of a patient suffering for a giant retroperitoneal extra-gastrointestinal stromal tumor, complicated with intra-tumoral hemorrhage. The particularity of this case is the presence of the intra-tumoral hemorrhage in a retroperitoneal extragastrointestinal stromal tumor that grew rapidly in volume (in 1 week).

scholarly journals A gastrointestinal stromal tumor: Case report

2002 ◽  
Vol 55 (9-10) ◽  
pp. 423-426
Author(s):  
Viktor Till ◽  
Matilda Djolai ◽  
Borut Pilipovic ◽  
Slavica Senicar ◽  
Ljiljana Hadnadjev ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Small Intestine ◽  
Case Report ◽  
Gastrointestinal Stromal Tumor ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Gastrointestinal Stromal Tumors ◽  
Abdominal Cavity ◽  
Stromal Tumor ◽  
Stromal Tumors

Introduction Gastrointestinal stromal tumors represent extremely rare tumors of the gastrointestinal system, especially when localized on the small intestine. Case report We report a case of a female patient, with recurrent gastrointestinal bleeding and severe anemia, caused by gastrointestinal stromal tumor of the small intestine. After negative endoscopic findings, she underwent radiological examination of the small intestine. Primary diagnostic radiological evaluation included: small intestine passage enteroclysis, computed tomography of the abdominal cavity and selective angiographic study of the three major aortic branches that supply the gastrointestinal tract in the abdomen (celiac axis, superior mesenteric artery and inferior mesenteric artery). Secondly, ultrasound of abdominal cavity was performed. Findings of small intestine passage and enteroclysis were negative. The tumor was visualized by computed tomography and ultrasound, but without distinctive anatomical localization in the abdominal cavity. Discussion The diagnostic dilemma has been resolved by using selective angiographic examination of celiac axis and superior mesenteric artery and thus a tumor formation was visualized in the mesenterium of the small intestine. Radiological findings were confirmed by surgery. Histopathological findings were positive for gastrointestinal stromal tumor. Conclusion Gastrointestinal stromal tumors of the small intestine rarely cause recurrent bleeding, but they should be included in differential diagnosis.

scholarly journals A Case Report of a Metastatic Gastrointestinal Stromal Tumor Occurring in Femur

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Chang-kun Zheng ◽  
Wu-Sheng Kan ◽  
Peng Li
Keyword(s):  
Small Intestine ◽  
Case Report ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Tumor Recurrence ◽  
Gastrointestinal Stromal Tumour ◽  
Metastatic Site ◽  
Stromal Tumors ◽  
Mesenchymal Neoplasms

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms that most commonly affect the stomach or small intestine, but can occur anywhere throughout the gastrointestinal tract. To the best of our knowledge, few cases have been reported in the literature about the femur metastasis of GIST. This paper describes a metastasis of a gastrointestinal stromal tumour (GIST) to the femur in a 62-year-old male, 2 years after treatment for a gastric primary. There were no signs of tumor recurrence at followup after 12 mo. This case suggests that the femur can be a potential metastatic site of GIST.

scholarly journals Massive hemorrhage of upper gastrointestinal tract caused by gastrointestinal stromal tumor of the stomach: Case report

2012 ◽  
Vol 65 (7-8) ◽  
pp. 341-345
Author(s):  
Nenad Lalovic ◽  
Nikolina Dukic-Vladicic ◽  
Radmil Maric ◽  
Mirjana Cuk ◽  
Milan Simatovic ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Digestive System ◽  
Massive Hemorrhage ◽  
Stromal Tumor ◽  
Acute Bleeding ◽  
Stromal Tumors ◽  
Upper Gastrointestinal

Introduction. Acute bleeding from the upper gastrointestinal system is a medical emergency which is followed by high mortality rate, ranging from 6 to 15% in spite of modern diagnostic methods and treatment. Bleeding from the upper gastrointestinal system may be caused by gastrointestinal stromal tumors of the stomach, which are mainly characterized by occult bleeding, while profuse bleeding rarely occurs accompanied by hemorrhagic shock. Gastrointestinal stromal tumors of stomach are the most common mesenchimal tumors of the gastrointestinal tract. Case Report. In our study we showed a 60-year-old female patient with profuse bleeding from the stomach and the clinical picture of severe hemorrhagic shock, caused by gastrointestinal stromal tumor. An ovoid junction, raised towards the lumen, covered with ulcerated mucosa in several places and followed by massive arterial bleeding was found intraoperatively, after the performed gastrotomy. Histopathological examination with immunohistochemical analysis confirmed that this was a gastrointestinal stromal tumor of the stomach. Discussion. Acute bleeding from the digestive system is a sudden and serious condition of the body. Urgent esophagogastroduodenoscopy is a sensitive and specific diagnostic and therapeutic method of choice. Massive bleeding from the upper gastrointestinal tract is very rarely caused by gastrointestinal stromal tumors, whose clinical picture is very heterogeneous and depends on tumor size and location. Abundant bleeding from the tumor is an indication for urgent surgical intervention. Conclusion. According to the literature massive hemorrhage of the upper digestive system can rarely be caused by gastrointestinal stromal tumor of the stomach. It is shown that abundant hemorrhage of the upper digestive tract can be caused with gastric gastrointestinal stromal tumor. Surgical resection is the main form of treatment of gastrointestinal stromal tumors of the digestive system and bleeding from these tumors caused by failure of endoscopic hemostasis.

scholarly journals Spontaneous rupture of a giant gastrointestinal stromal tumor of the jejunum: a case report and literature review

2014 ◽  
Vol 12 (1) ◽  
pp. 153 ◽  
Author(s):  
Shun-ichi Misawa ◽  
Misuzu Takeda ◽  
Hiroto Sakamoto ◽  
Yasushi Kirii ◽  
Hiroyoshi Ota ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Gastrointestinal Stromal Tumor ◽  
Spontaneous Rupture ◽  
Stromal Tumor

scholarly journals Skeletal Muscle Metastasis of a GIST: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Olga D. Savvidou ◽  
George D. Chloros ◽  
Georgios D. Agrogiannis ◽  
Penelope Korkolopoulou ◽  
Georgios N. Panagopoulos ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Case Report ◽  
Soft Tissue ◽  
Gastrointestinal Stromal Tumors ◽  
Review Of The Literature ◽  
Soft Tissue Metastasis ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Skeletal Muscle Metastasis ◽  
Muscle Metastasis

Gastrointestinal stromal tumors (GISTs) are the most common malignant mesenchymal tumors of the gastrointestinal tract. The most common sites of metastasis are the liver and the peritoneum, whereas metastasis to soft tissue is rare. The authors present the case of a 78-year-old male with a soft tissue metastasis of a GIST and the current literature is reviewed.

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