scholarly journals Macular and Peripapillary Choroidal Thickness Measured by Enhanced Depth Imaging Optical Coherence Tomography in Chinese Pregnant Women and Healthy No-Pregnant Women

Author(s):  
Hanfei Wu ◽  
Haishuang Lin ◽  
Huanjie Fang ◽  
Mengting Ruan ◽  
Jiawei Zhao

Abstract Purpose: To evaluate macular, peripapillary choroidal thickness and retinal nerve fiber layer (RNFL) thickness in different trimesters and compare the measurements with those of healthy non-pregnant women. Methods: A prospective comparative study included 45 healthy pregnant women in first trimester, 90 women in second, 45 women in third trimesters and 45 healthy no-pregnant women as the control group. Macular choroidal thickness was measured at the subfoveal, 1mm temporal and 1mm nasal to the fovea using enhanced depth imaging optical coherence tomography (EDI-OCT). Peripapillary choroidal thickness and RNFL thickness parameters were automatically calculated by the Spectralis OCT. These parameters were analyzed among groups. Results: The subfoveal, temporal and nasal choroidal thickness were all significantly thicker in second trimesters, comparing with those parameters in first, third trimesters and the control group (all P<0.05). The peripapillary choroidal thickness was significantly increased at temporal, nasal, nasal inferior, temporal inferior and global positions during pregnancy among the 4 groups (all P<0.05). The RNFL thickness was also significantly increased in pregnant women at nasal superior and nasal inferior quadrants.Conclusions: Our results suggested that macular choroidal thickening appeared in second trimester. And peripapillary choroidal thickness and RNFL thickness also became thickening in pregnant women comparing with no-pregnant women as a whole.

2016 ◽  
Vol 27 (4) ◽  
pp. 428-432
Author(s):  
Mónica Loureiro ◽  
Ana Cristina Braga ◽  
Dália Meira ◽  
Paula Sepúlveda ◽  
Luís Agrelos ◽  
...  

Purpose To assess the impact of metabolic syndrome (MetS) on the peripapillary choroidal thickness (PPCT) and to characterize the PPCT in a Portuguese population. Methods This prospective study included 104 eyes. Detailed medical and ophthalmic examinations were performed; the PPCT was measured by spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging (EDI) modality. The PPCT changes with MetS, as well as with other clinical and demographic factors, were investigated. Results The mean PPCT was 142.4 ± 54.0 µm (58-303 µm); it was thickest superiorly, followed by the temporal, nasal, and inferior sectors. The PPCT was significantly associated with axial length (p<0.001), age (p = 0.001), intraocular pressure (IOP) (p = 0.041), weight (p = 0.015), and arterial hypertension (p = 0.044). The presence of MetS was associated with thinner PPCT in all sectors, being statistically significant in the temporal (p = 0.032) and inferotemporal (p = 0.034) sectors. Conclusions The choroidal thickness was significantly less in temporal and inferotemporal sectors in patients with MetS than in controls. This may suggest vascular insufficiency around the optic nerve head.


2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Jun Zhang ◽  
Huiyun Wang ◽  
Qiubo Yu ◽  
Qihu Tong ◽  
Qinkang Lu

The body changes markedly during pregnancy; each system behaves differently from a nonpregnant state. As the eyes are the only windows to see directly what is going on in the internal environment, more and more researches have been done to explain the association between ocular changes and the physiological and pathological changes during pregnancy. The choroid is one of the critical parts of the eye, providing nutrition. And abnormal choroid may result in ocular dysfunction and visual problems. As the optical coherence tomography develops, a rapid, direct, noninvasive, and nontoxic way is available to obtain the choroid situation of pregnant women, which may explain the mechanism of pregnancy-related eye diseases. This review would summarize relevant original articles published from January 1, 2008 to December 1, 2016 to assess the changes of choroidal thickness (CT) with enhanced depth imaging optical coherence tomography (EDI-OCT) during pregnancy. And the relationship between choroidal thickness changes and pregnancy remains uncertain. To our knowledge, this is the first review of EDI-OCT in assessing the choroidal thickness of the pregnant women.


2013 ◽  
Vol 6 (4) ◽  
pp. 34-38 ◽  
Author(s):  
Yuriy Sergeyevich Astakhov ◽  
Svetlana Georgiyevna Belekhova

66 healthy people (124 eyes) with different degrees of myopia and emmetropia were examined using enhanced depth imaging optical coherence tomography (EDI-OCT) using the “Spectralis OCT”. It was found that the choroid in subjects with medium and high degrees of myopia was significantly thinner than that in the control group. In the study, a negative correlation was found between the subfoveal choroidal thickness and the degree of myopia (r = -0.75, p < 0.0001). It was also found that the subfoveal choroidal thickness decreased for each diopter of myopia by approximately 18.03 μm.


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