scholarly journals Clinical Outcomes of Single-Step Transepithelial Photorefractive Keratectomy and Off-Flap Epipolis-Laser in Situ Keratomileusis in Moderate to High Myopia: 12-Month Follow-Up

2021 ◽  
Author(s):  
Yunjie Zhang ◽  
Tiankun Li ◽  
Zhangliang Li ◽  
Mali Dai ◽  
Qinmei Wang ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Contrast Sensitivity ◽  
High Myopia ◽  
Single Step ◽  
Self Control ◽  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy ◽  
Group 3

Abstract Background To compare the quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy (TPRK) and off-flap epipolis-laser in situ keratomileusis (Epi-LASIK) in moderate to high myopia. Methods In this prospective self-control study, we included patients with moderate to high myopia who were randomized to undergo TPRK in one eye and Epi-LASIK in the other eye. Twelve-month follow-up results for visual acuity, refraction, ocular high-order aberrations, contrast sensitivity, postoperative pain, epithelial healing, and haze grade were assessed. Results A total of 64 eyes (32 patients) were enrolled in the study. More eyes completed re-epithelialization in the TPRK group than in the Off-flap Epi-LASIK group 3–4 days postoperatively, while all eyes completed re-epithelialization by seven days. More eyes achieved a visual acuity (both UDVA and CDVA) of better than 20/20 in the TPRK group than in the Off-flap Epi-LASIK group. The ± 0.50 D predictability for correction of the spherical equivalent (SE) was higher in the eyes of the TPRK group (91%) than in those of the off-flap Epi-LASIK group (80%) 12 months after surgery. No significant differences in ocular aberrations, including coma, spherical, and trefoil, were found between the two groups at 12 months. There were also no significant differences in visual acuity, contrast sensitivity, pain, and haze grading between the two groups. Conclusions Both TPRK and off-flap Epi-LASIK are safe, effective, and predictable treatments for moderate to high myopia with comparable surgical outcomes. Trial registration: This study was retrospectively registered on ClinicalTrial.gov (NCT05060094, 17/09/2021).

scholarly journals Effect of Photorefractive Keratectomy and Laser in situ Keratomileusis in High Myopia on logMAR Visual Acuity and Contrast Sensitivity

2003 ◽  
Vol 46 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Hana Langrová ◽  
Matthias Derse ◽  
Dagmar Hejcmanová ◽  
Alena Feuermannová ◽  
Pavel Rozsíval ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Contrast Sensitivity ◽  
High Myopia ◽  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy ◽  
Spherical Equivalent ◽  
Spatial Frequencies ◽  
Quality Of Vision

Purpose: To compare effect of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) on contrast sensitivity (CS) and best corrected visual acuity (BCVA) in high myopia. Methods: 38 myopes (PRK) and 31 patients (LASIK) were examined before and 1, 3, 6, and 12 months postoperatively. Mean preoperative spherical equivalent was -8.0 ± 1.7D (PRK) and -9.2 ± 2.1D (LASIK). CS was tested on a computerized system of the Contrast Sensitivity 8010 Type at 6 spatial frequencies (0.74 and 29.55 c/deg), BCVA was measured on logMAR charts. Results: At 12 months postoperatively, mean spherical equivalent was -0.6 ± 1.0D (PRK) and -1.0 ± 0.8D (LASIK). Postoperative values of CS were significantly higher in the PRK group, except for spatial frequencies of 3.69 and 7.39 c/deg up to 3 months postoperatively. The initial significant decrease of BCVA lasted up to 6 months after PRK. In the LASIK group BCVA was not significantly different from its preoperative level at the 3-months follow-up. Conclusions: The significant improvement of CS after PRK suggest that PRK can improve quality of vision in eyes with high myopia. Although recovery of BCVA after LASIK was faster than after PRK, there may be a persistent decrease in CS.

scholarly journals Effect of Flat Cornea on Visual Outcome after LASIK

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Engy Mohamed Mostafa
Keyword(s):  
Visual Acuity ◽  
High Myopia ◽  
Visual Outcome ◽  
Laser In Situ Keratomileusis ◽  
Refractive Outcome ◽  
Corrected Distance Visual Acuity ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Purpose. To evaluate the effect of preoperative and postoperative keratometry on the refractive outcome after laser in situ keratomileusis (LASIK) for moderate and high myopia.Methods. Records of 812 eyes (420 patients) with myopia ≥−6 D who had LASIK at Sohag Laser Center, Egypt, from January 2010 to November 2013, were retrospectively analyzed. Main outcome measures were postoperative corrected distance visual acuity (CDVA), postoperative spherical equivalence, and postoperativeQfactor.Results. LASIK was performed in 812 eyes (mean age21.8±5.2years). Patients were grouped according to the degree of preoperative myopia into three groups: Group 1, −6 D to −7.9 D; Group 2, −8 to −9.9 D; and Group 3, −10 to −12 D. The refractive outcome among the different myopia groups was stratified by pre- and postoperative keratometry. A trend toward greater undercorrection was noted in eyes with preoperative keratometry <43.5 D compared with those with steeper keratometry >46 D in all myopia groups. The undercorrection was also noted in postoperative keratometry groups <35 D.Conclusions. Preoperative and postoperative keratometry appeared to influence the refractive outcome especially in high myopic eyes.

scholarly journals Effect of Transepithelial Photorefractive Keratectomy without Mitomycin C in the Treatment of Femtosecond Laser In Situ Keratomileusis Corneal Flap Complications

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Jing Wang ◽  
Weiqian Cao ◽  
Liming Tao
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Mitomycin C ◽  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy ◽  
Distance Visual Acuity ◽  
Uncorrected Distance Visual Acuity ◽  
Haze Formation

Purpose. To assess the efficacy and safety of transepithelial photorefractive keratectomy (TPRK) without mitomycin C as treatment for femtosecond laser in situ keratomileusis (FS-LASIK) corneal flap complications. Methods. Eight patients with corneal flap complications that occurred after FS-LASIK (five with eccentric flaps, two with buttonhole flaps, and one with a thick flap) were included in the study. Patients were treated with TPRK without mitomycin C between two weeks and twelve months after surgery. The postoperative manifest refraction, uncorrected distance visual acuity, and haze formation were assessed during six months of follow-up. Results. The mean manifest refractive spherical and cylinder refraction was 0.16 ± 0.26 and −0.44 ± 0.33 diopters, respectively, at six months postoperatively. The uncorrected distance visual acuity was above 20/25 in all patients after six months of follow-up. No haze formation was detected. Conclusions. TPRK without mitomycin C appears to be a safe and effective treatment for FS-LASIK corneal flap complications.

scholarly journals Correction of Myopia and Myopic Astigmatism by Femtosecond Laser in Situ Keratomileusis

2019 ◽  
Vol 75 (2) ◽  
pp. 65-71
Author(s):  
Tereza Řeháková ◽  
Věra Veliká ◽  
Naďa Jirásková
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
High Myopia ◽  
Laser In Situ Keratomileusis ◽  
Patient’S Satisfaction ◽  
The Mean ◽  
One Year ◽  
Myopic Astigmatism

Aim: We analysed one-year refractive results and the incidence of complications in patients with correction of low-to-high myopia or myopic astigmatism by femtosecond laser in situ keratomileusis (FS-LASIK) using femtosecond laser LenSx® (Alcon, Fort Worth, Texas, USA) a excimer laser Excimer Amaris 500 (Schwind eye-tech-solutions GmbH and Co KG, Kleinostheim, Germany). Methods: To the retrospective study were included 171 eyes of 87 patients (38 men, 49 women) who underwent correction of myopia and myopic astigmatism by FS-LASIK in the outpatient Department of Ophthalmology, University Hospital in Hradec Králové between 2013-2017. We assessed uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA), subjective refraction, central corneal thickness (CCT) in the thinnest point, patient’s satisfaction and the incidence of complications in the one-year follow-up period. Results: At the time of laser procedure the mean patient‘s age was 29,26 ± 6,47 years (range 18 to 46 years). In 21 eyes was corrected myopia (range -6,5 to -2,5 D sph) and in 150 eyes myopic astigmatism (range -8,75 to -0,25 D sph and -3,0 to -0,25 D cyl). The mean preoperative UCVA 0,06 ± 0,08 (range 0,02 to 0,8) got better to 1,12 ± 0,17 (range 0,8 to 1,5) at the end of follow-up period. There wasn’t statistically significant change in BCVA between preoperative and postoperative values. Preoperative mean value of subjective refraction was -4,14 ± 1,43 D sph (range -8,5 to -1 D sph) and -0,57 ± 0,58 D cyl (range -3 to 0 D cyl) and after 12 months -0,02 ± 0,16 D sph (range -0,1 to 0,75 D sph) and -0,01 ± 0,1 D cyl (range -0,5 to 0,5 D cyl). The initial mean CCT was 554,76 ± 30,07 μm (range 485 to 660 μm), after 6 months 494,06 ± 34,99 μm (range 421 to 594 μm) and after 12 months 492,92 ± 34,55 μm (range 411 to 592 μm). We observed peroperative complications in 3 eyes. The suction loss of femtosecond laser occurred during flap creation due to sudden eye movement. Postoperatively in one case we enrolled flap pucker first postoperative day. In other case flap dislocation occurred after abdonimal surgery under general anesthesia which was performed 3 months after refractive procedure and we had to indicate flap reposition. The mean grade of patient’s satisfaction was at the end of follow-up period 1,04. The most often complaints were the sensation of dry eye (10 patients) and blurry vision during computer working, inadequate lighting and fatique (6 pacients). Conclusions: According to our experience correction of low-to-high myopia or myopic astigmatism by using FS-LASIK is an effective, relatively safe and predictable method. The basic assumption of good postoperative results and patient’s satisfaction is thorough and comprehensive preoperative examination with respect to indication criteria.

scholarly journals Twelve-Year Follow-Up of Laser In Situ Keratomileusis for Moderate to High Myopia

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Tetsuya Ikeda ◽  
Kimiya Shimizu ◽  
Akihito Igarashi ◽  
Sumie Kasahara ◽  
Kazutaka Kamiya
Keyword(s):  
High Myopia ◽  
Central Corneal Thickness ◽  
Pearson Correlation ◽  
Corneal Thickness ◽  
Laser In Situ Keratomileusis ◽  
Manifest Refraction ◽  
Observation Period

Purpose. To assess the long-term clinical outcomes of conventional laser in situ keratomileusis (LASIK) for moderate to high myopia.Methods. We retrospectively examined sixty-eight eyes of 37 consecutive patients who underwent conventional LASIK for the correction of myopia (−3.00 to −12.75 diopters (D)). At 3 months and 1, 4, 8, and 12 years postoperatively, we assessed the safety, efficacy, predictability, stability, mean keratometry, central corneal thickness, and adverse events.Results. The safety and efficacy indices were0.82±0.29and0.67±0.37, respectively, 12 years postoperatively. At 12 years, 53% and 75% of the eyes were within 0.5 and 1.0 D, respectively, of the targeted correction. Manifest refraction changes of −0.74±0.99 D occurred from 3 months to 12 years after LASIK (p<0.001). We found a significant correlation of refractive regression with the changes in keratometric readings from 3 months to 12 years postoperatively (Pearson correlation coefficient,r=-0.28,p=0.02), but not with the changes in central corneal thickness (r=-0.08,p=0.63). No vision-threatening complications occurred in any case.Conclusions. Conventional LASIK offered good safety outcomes during the 12-year observation period. However, the efficacy and the predictability gradually decreased with time owing to myopic regression in relation to corneal steepening.

Comparison of laser in situ keratomileusis and photorefractive keratectomy results: Long-term follow-up

2008 ◽  
Vol 34 (9) ◽  
pp. 1527-1531 ◽  
Author(s):  
Takashi Miyai ◽  
Kazunori Miyata ◽  
Ryohei Nejima ◽  
Masato Honbo ◽  
Keiichiro Minami ◽  
...  
Keyword(s):  
Laser In Situ Keratomileusis ◽  
Photorefractive Keratectomy ◽  
Long Term Follow Up

scholarly journals Outcomes of Wavefront-Optimized Laser-Assisted In-Situ Keratomileusis and Photorefractive Keratectomy for correction of Myopia and Myopic Astigmatism over One Year Follow-Up

2018 ◽  
Vol 12 (1) ◽  
pp. 256-263 ◽  
Author(s):  
Mohammad M. Shehadeh ◽  
Mohammad T. Akkawi ◽  
Ammar A. Aghbar ◽  
Muna T. Musmar ◽  
Malak N Khabbas ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Excimer Laser ◽  
Photorefractive Keratectomy ◽  
Distance Visual Acuity ◽  
Visual Outcomes ◽  
Corrected Distance Visual Acuity ◽  
One Year ◽  
Myopic Astigmatism

Background: Laser corneal refractive surgery suits, technology and nomograms are improving with time. This may improve the refractive and visual outcomes of the patients. Objectives: To evaluate the safety, efficacy, stability, and predictability of wavefront-optimized photorefractive keratectomy and Laser-assisted in-situ keratomileusis in patients with myopia and myopic astigmatism over 1-year using WaveLight® EX500 Excimer Laser machine. Methods: In this prospective cohort study, refractive and visual outcomes in 596 eyes (365 patients), either having myopia or myopic astigmatism were assessed. Patients were divided into Two groups: 1) Patients who underwent PRK (53 eyes have myopia and 217 eyes have myopic astigmatism), 2) Patients who underwent LASIK (53 eyes have myopia and 273 eyes have myopic astigmatism). Results: At 12 months postoperatively 94.3% of the myopic patients reached their preoperative best corrected distance visual acuity at the final one year follow up visit post PRK and LASIK. In patients with myopic astigmatism who underwent LASIK and PRK, 95.2%, and 96.3% of the patients reached their preoperative best corrected distance visual acuity at the final one year follow up visit post LASIK and PRK, respectively. The efficacy and safety indices were 1.00 or more for all groups with no eye lost any line of best corrected distance visual acuity. Conclusion: Our study results confirm the excellent efficacy, safety, good predictability and stability of myopia / myopic astigmatism correction by either wavefront- optimized LASIK or PRK over 1-year follow-up without significant differences between them using the WaveLight® EX500 excimer laser system.

Sign in / Sign up

Export Citation Format

Share Document