Chemical Composition and Repellency Effect of Ferulago Angulate Plant Against Malaria Vector, Anopheles Stephensi

Author(s):  
Masoumeh Pirmohammadi ◽  
Mansoureh Shayeghi ◽  
Mohammad Reza Abai ◽  
Hassan Vatandoost ◽  
Sara Rahimi ◽  
...  

Abstract BackgroundMalaria is a health problem globally. There are several vector control measures. Using repellent to protect human from biting of vectors is one of the best ways. The aim of this study is to evaluate the efficacy of plant against biting of malaria vector, An.stephensi under laboratory conditions.MethodsChemical constituents of Ferulago angulate plant were determined by using gas chromatography-mass spectrometry. Efficacy and the protection time of plant were evaluated on Anopheles stephensi . ResultsA total of 40 compounds were identified in plant. Flourensiadiol (17.4%) dehydro-sabina keton (13.3%), β-maaliene (8.8%) was the highest in the plant. The mean assessed protection time and efficacy for plant was 60 and 100 minutes respectively. ED50 and ED90 values for this plant were 18.12 and 93.19 µl /cm2 respectively.ConclusionResults showed that plant has an acceptable protection time, therefore, this plant could be considered as a good herbal repellent against anopheles mosquitoes.

Author(s):  
Carla Maria Mariano Fernandez ◽  
◽  
Fabiana Brusco Lorenzetti ◽  
Sirlene Adriana Kleinubing ◽  
Joao Paulo Pinguello de Andrade ◽  
...  

The present study aimed to analyze the chemical composition of the essential oil from Garcinia gardneriana (Planchon & Triana) Zappi leaves and fruits, and to determine its acaricidal activity on Rhipicephalus microplus by larval packet test and larvicidal action on Aedes aegypti by larval immersion test. The chemical analysis of the essential oil by gas chromatography-mass spectrometry identified sesquiterpene hydrocarbons and oxygenated sesquiterpenes in bacupari leaves and fruits, and α-cedrene, α-chamigrene, α-trans-bergamotene, and β-curcumene as major compounds. Essential oil from leaves of G. gardneriana presented acaricidal activity on R. microplus (LC50 = 4.8 mg/mL; LC99 = 10.8 mg/mL) and larvicidal effect on A. aegypti (LC50 = 5.4 mg/mL; LC99 = 11.6 mg/mL), whereas essential oil from the fruits of G. gardneriana showed LC50 = 4.6 mg/mL and LC99 = 8.9 mg/mL against R. microplus and LC50 = 6.4 mg/mL and LC99 = 13.9 mg/mL against A. aegypti. These results thus demonstrate the potential acaricidal and larvicidal activity of essential oil of G. gardneriana, offering new perspectives for the realization of bioassays from this essential oil.


2014 ◽  
Vol 9 (2) ◽  
pp. 1934578X1400900
Author(s):  
Rajesh K. Joshi

The essential oil obtained from the aerial parts of Croton bonplandianus Baill. was analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). A total of 37 compounds have been identified, representing 96.2% of the total oil. The main constituents were identified as β-caryophyllene (16.7%), germacrene D (14.7%), borneol (8.3%), Z-β-damascenone (6.(%), isobornyl acetate (6.2%), α-humulene (6.1%), germacrene A (5.2%) and caryophyllene oxide (4.5%). The oil was rich in sesquiterpene hydrocarbons (60.1%).


2009 ◽  
Vol 4 (3) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Akinola O. Ogunbinu ◽  
Guido Flamini ◽  
Pier L. Cioni ◽  
Isiaka A. Ogunwande ◽  
Sunday O. Okeniyi

The chemical composition of the essential oils from the leaves and stem bark of Eclipta prostrata (L.) L. and the aerial parts of Vernonia amygdalina Delile (Asteraceae) have been analyzed by capillary gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). The investigation led to the identification of 33 and 30 compounds in the oils of the leaves and stem of E. prostrate, respectively, and 40 compounds in the oil of V. amygdalina. While the oil of the leaves of E. prostrata was highly dominated by sesquiterpenoids (89.3%), the stem bark was comprised of sesquiteprenoids (47.7%), straight chain hydrocarbons (25.6%) and monoterpenoids (11.1%). The main constituents of both oils were β-caryophyllene (47.7% and 15.9%) and α-humulene (31.8 and 12.9%) in the leaves and stem, respectively. In addition, ( E)-β-farnesene (10.0%) was also identified in significant amount in the stem bark. On the other hand, the major component of V. amygdalina oil was α-muurolol (45.7%).


2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Xiao-Meng Wei ◽  
Shan-Shan Guo ◽  
Hua Yan ◽  
Xian-Long Cheng ◽  
Feng Wei ◽  
...  

Essential oils obtained from many plants showed various kinds of insecticidal properties; some of them have been considered as alternative insecticides for pest control. The present study was aimed at determining the chemical composition of the essential oil from the roots of Bupleurum bicaule Helm, as well as evaluating the contact and repellent activities of the oil and four identified compounds against Lasioderma serricorne and Liposcelis bostrychophila adults. The essential oil was extracted by hydrodistillation, and its components were analyzed by gas chromatography-mass spectrometry (GC-MS). 26 components were determined and the main compounds included trans-2-isopropylbicyclo[4.3.0]non-3-en-8-one (25.9%), 4,5-dimethyl-1,2,3,6,7,8,8a,8b-octahydrobiphenylene (23.5%), and 1,4-dimethoxy-2-tert-butylbenzene (4.3%). It was found that the essential oil exhibited contact toxicity against L. serricorne (LD50 = 11.91 μg/adult), but the contact toxicity against L. bostrychophila could not be observed. The essential oil also showed strong repellent activity against L. serricorne with percent repellency of 100% at 78.63 nl/cm2. Four chemical compounds, 1,4-dimethoxy-2-tert-butylbenzene, bornyl acetate, (2E,4E)-2,4-nonadienal, and β-bisabolene, exhibited various levels of bioactivities. The experimental results indicated that the essential oil of B. bicaule and its individual compounds could be used in insecticidal and repellent strategies for stored product insects.


2020 ◽  
Vol 58 (5) ◽  
pp. 682-689 ◽  
Author(s):  
Roberta Pacifici ◽  
Simona Pichini ◽  
Manuela Pellegrini ◽  
Maria Concetta Rotolo ◽  
Raffaele Giorgetti ◽  
...  

AbstractBackground“Light cannabis” is a product legally sold in Europe with Δ9-tetrahydrocannabinol (THC) concentration lower than 0.2% and variable cannabidiol (CBD) content. We studied THC and CBD excretion profiles in blood, oral fluid (OF) and urine after smoking one or four light cannabis cigarettes.MethodsBlood, OF and urine samples were obtained from six healthy light cannabis consumers after smoking one 1 g cigarette containing 0.16% THC and 5.8% CBD and from six others after smoking four 1 g cigarettes within 4 h. Sample collection began 0.5 and 4.5 h after smoking one or four cigarettes, respectively. Cannabinoid concentrations were quantified by gas chromatography-mass spectrometry (GC-MS).ResultsAt the first collection, the highest THC and CBD concentrations occurred in blood (THC 7.0–10.8 ng/mL; CBD 30.2–56.1 ng/mL) and OF (THC 5.1–15.5 ng/mL; CBD 14.2–28.1 ng/mL); similar results occurred 0.5 h after the last of four cigarettes in blood (THC 14.1–18.2 ng/mL, and CBD 25.6–45.4 ng/mL) and OF (THC 11.2–24.3 ng/mL; CBD 14.4–37.0 ng/mL). The mean OF to blood ratio ranged from 0.6 to 1.2 after one and 0.6 to 1.9 after four light cannabis cigarettes. THC/CBD ratios in blood and OF were never greater than 2. Urinary 11-nor-9-carboxy-THC concentrations peaked 8 h after one and four cigarettes.ConclusionsOF was a valuable alternative to blood in monitoring consumption of light cannabis. Blood and OF THC/CBD concentration ratios, never exceeded 2, possibly providing a useful biomarker to identify light cannabis vs illegal higher THC cannabis use, where THC/CBD ratios are generally greater than 10.


2011 ◽  
Vol 6 (11) ◽  
pp. 1934578X1100601
Author(s):  
Ying Zhang ◽  
Jianglin Zhao ◽  
Jihua Wang ◽  
Tijiang Shan ◽  
Yan Mou ◽  
...  

The volatile oil, obtained by hydrodistillation from Fusarium tricinctum, the endophytic fungus isolated from Paris polyphylla var. yunnanensis, was analyzed by gas chromatography-mass spectrometry (GC-MS). trans-1,2,3,3a,4,7a-Hexahydro-7a-methyl-5H-inden-5-one (73.1%), 2-methylene-4,8,8-trimethyl-4-vinyl bicyclo [5.2.0] nonane (12.0%), and 2,6-dimethyl-6-(4-methyl-3-pentenyl) bicyclo [3.1.1] hept-2-ene (4.5%) were the major compounds of the 15 identified components accounting for 95.4% of the volatile oil. The antimicrobial activity of the volatile oil was assayed against eight bacteria and two fungi. The minimum inhibitory concentration (MIC) values of the volatile oil against the test bacteria ranged from 25 to 45 μg/mL. The MIC values against the fungi Candida albicans and Magnaporthe oryzae were 100 and 225 μg/mL, respectively. The mean inhibitory concentration (IC50) values of the volatile oil against the test bacteria ranged from 17.8 to 31.6 μg/mL, and those of the volatile oil against C. albicans and M. oryzae were 84.3 and 204.3 μg/mL, respectively.


Holzforschung ◽  
2020 ◽  
Vol 74 (8) ◽  
pp. 745-753
Author(s):  
Walter Fiacre Bédounguindzi ◽  
Kévin Candelier ◽  
Prosper Edou Engonga ◽  
Stéphane Dumarçay ◽  
Marie-France Thévenon ◽  
...  

AbstractDacryodes edulis (G. Don) H.J. Lam resin was hydro-distilled to recover essential oil (EO), and further purified to produce a heavy fraction constituting less volatile compounds. Chemical composition was investigated by gas chromatography-mass spectrometry (GC-MS), and indicated that different monoterpenes and triterpenes were present depending on the analyzed fraction. Bioassays were performed on the different fractions to evaluate their anti-fungal and anti-termite properties. Results indicated that crude resin, its heavy fraction and its EO all had proved termicidal properties, which decrease on drying for EO and crude resin due to evaporation of monoterpenes. Conversely, no anti-fungal properties were observed for any fraction. Dacryodes edulis resin is therefore a new valuable bioactive ingredient for the formulation of wood protection products with anti-termite properties.


2019 ◽  
Vol 14 (7) ◽  
pp. 1934578X1985749
Author(s):  
Jorge A. Pino ◽  
María Milagros Dueñas-Mendoza ◽  
Leoncio Solís-Quispe

The chemical composition of the essential oil from aerial parts of Minthostachys acris Schmidt-Leb. grown in Cuzco was studied. A total of 59 volatile compounds were identified by gas-chromatography-flame ionization detector and gas chromatography-mass spectrometry in the essential oil obtained by steam distillation, of which the most prominent were pulegone (54.4%), cis-menthone (11.0%), and thymol (6.3%).


2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1985099 ◽  
Author(s):  
Tran Hui Thai ◽  
Nguyen Thi Hien ◽  
Le Ngoc Diep ◽  
Mathieu Paoli ◽  
Joseph Casanova ◽  
...  

Conifers are well represented in Vietnam where a new pine species has been recently discovered in Son La province: Pinus cernua, synonym P. armandii ssp. xuannhaensis. The compositions of needle, cone, and branch oils have been investigated by gas chromatography (retention index), gas chromatography-mass spectrometry, and 13C nuclear magnetic resonance. Myrcene (47.0%) was the main component of needle oil, followed by β-pinene (28.4%) and α-pinene (12.5%). Branch oil also contained myrcene (32.8%), α-pinene (17.9%), β-pinene (9.8%), and a high content of limonene (20.0%). Finally, cone oil displayed α-pinene (44.1%) beside myrcene (11.5%), β-pinene (8.1%), and limonene (5.8%).


1995 ◽  
Vol 46 (6) ◽  
pp. 1259 ◽  
Author(s):  
GC Hillbrick ◽  
DJ Tucker ◽  
GC Smith

This study examined the differences in the chemical composition of the lipid extracted from the fleeces of intact and gonadectomized Australian cashmere goats (Capra hircus laniger). Lipid was extracted with either petroleum ether or chloroform/methanol, and analysed by gas chromatography and gas chromatography/mass spectrometry. A large number of buck specific fatty acids (29), which could be potential pheromones, were identified or tentatively identified. The fatty acid composition of buck fleece lipid is more complex than previously reported.


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