scholarly journals Decision Tree Model Predicts Live Birth after Surgery for Moderate-to-Severe Intrauterine Adhesions

Author(s):  
Ru Zhu ◽  
Hua Duan ◽  
Wenbin Xu ◽  
Sha Wang ◽  
Lu Gan ◽  
...  

Abstract Background: After treatment of intrauterine adhesions, the rate of re-adhesion is high and the pregnancy outcome unpredictable and unsatisfactory. This study established and verified a decision tree predictive model of live birth in patients after surgery for moderate-to-severe intrauterine adhesions (IUAs).Methods: A retrospective observational study initially comprised 394 patients with moderate-to-severe IUAs diagnosed via hysteroscopy. The patients underwent hysteroscopic adhesiolysis from January 2013 to January 2017, in a university-affiliated hospital. Follow-ups to determine the rate of live birth were conducted by telephone for at least the first postoperative year. A classification and regression tree algorithm was applied to establish a decision tree model of live birth after surgery.Results: Within the final population of 374 patients, the total live birth rate after treatment was 29.7%. The accuracy of the model was 83.8%, and the area under the receiver operating characteristic curve (AUC) was 0.870 (95% CI 7.699-0.989). The root node variable was postoperative menstrual pattern. The predictive accuracy of the multivariate logistic regression model was 70.3%, and the AUC was 0.835 (95% CI 0.667-0.962).Conclusions: The decision tree predictive model is useful for predicting live birth after surgery for IUAs; postoperative menstrual pattern is a key factor in the model. This model will help clinicians make appropriate clinical decisions during patient consultations.

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Ru Zhu ◽  
Hua Duan ◽  
Sha Wang ◽  
Lu Gan ◽  
Qian Xu ◽  
...  

Objective. To establish and validate a decision tree model to predict the recurrence of intrauterine adhesions (IUAs) in patients after separation of moderate-to-severe IUAs. Design. A retrospective study. Setting. A tertiary hysteroscopic center at a teaching hospital. Population. Patients were retrospectively selected who had undergone hysteroscopic adhesion separation surgery for treatment of moderate-to-severe IUAs. Interventions. Hysteroscopic adhesion separation surgery and second-look hysteroscopy 3 months later. Measurements and Main Results. Patients’ demographics, clinical indicators, and hysteroscopy data were collected from the electronic database of the hospital. The patients were randomly apportioned to either a training or testing set (332 and 142 patients, respectively). A decision tree model of adhesion recurrence was established with a classification and regression tree algorithm and validated with reference to a multivariate logistic regression model. The decision tree model was constructed based on the training set. The classification node variables were the risk factors for recurrence of IUAs: American Fertility Society score (root node variable), isolation barrier, endometrial thickness, tubal opening, uterine volume, and menstrual volume. The accuracies of the decision tree model and multivariate logistic regression analysis model were 75.35% and 76.06%, respectively, and areas under the receiver operating characteristic curve were 0.763 (95% CI 0.681–0.846) and 0.785 (95% CI 0.702–0.868). Conclusions. The decision tree model can readily predict the recurrence of IUAs and provides a new theoretical basis upon which clinicians can make appropriate clinical decisions.


Author(s):  
Yoni Cohen ◽  
Noga Nattiv ◽  
Sarit Avrham ◽  
Yuval Fouks ◽  
Michal Rosenberg Friedman ◽  
...  

Electronics ◽  
2021 ◽  
Vol 10 (16) ◽  
pp. 1903
Author(s):  
Long Zhao ◽  
Sanghyuk Lee ◽  
Seon-Phil Jeong

A personal credit evaluation algorithm is proposed by the design of a decision tree with a boosting algorithm, and the classification is carried out. By comparison with the conventional decision tree algorithm, it is shown that the boosting algorithm acts to speed up the processing time. The Classification and Regression Tree (CART) algorithm with the boosting algorithm showed 90.95% accuracy, slightly higher than without boosting, 90.31%. To avoid overfitting of the model on the training set due to unreasonable data set division, we consider cross-validation and illustrate the results with simulation; hypermeters of the model have been applied and the model fitting effect is verified. The proposed decision tree model is fitted optimally with the help of a confusion matrix. In this paper, relevant evaluation indicators are also introduced to evaluate the performance of the proposed model. For the comparison with the conventional methods, accuracy rate, error rate, precision, recall, etc. are also illustrated; we comprehensively evaluate the model performance based on the model accuracy after the 10-fold cross-validation. The results show that the boosting algorithm improves the performance of the model in accuracy and precision when CART is applied, but the model fitting time takes much longer, around 2 min. With the obtained result, it is verified that the performance of the decision tree model is improved under the boosting algorithm. At the same time, we test the performance of the proposed verification model with model fitting, and it could be applied to the prediction model for customers’ decisions on subscription to the fixed deposit business.


Author(s):  
Avijit Kumar Chaudhuri ◽  
Deepankar Sinha ◽  
Dilip K. Banerjee ◽  
Anirban Das

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1094
Author(s):  
Michael Wong ◽  
Nikolaos Thanatsis ◽  
Federica Nardelli ◽  
Tejal Amin ◽  
Davor Jurkovic

Background and aims: Postmenopausal endometrial polyps are commonly managed by surgical resection; however, expectant management may be considered for some women due to the presence of medical co-morbidities, failed hysteroscopies or patient’s preference. This study aimed to identify patient characteristics and ultrasound morphological features of polyps that could aid in the prediction of underlying pre-malignancy or malignancy in postmenopausal polyps. Methods: Women with consecutive postmenopausal polyps diagnosed on ultrasound and removed surgically were recruited between October 2015 to October 2018 prospectively. Polyps were defined on ultrasound as focal lesions with a regular outline, surrounded by normal endometrium. On Doppler examination, there was either a single feeder vessel or no detectable vascularity. Polyps were classified histologically as benign (including hyperplasia without atypia), pre-malignant (atypical hyperplasia), or malignant. A Chi-squared automatic interaction detection (CHAID) decision tree analysis was performed with a range of demographic, clinical, and ultrasound variables as independent, and the presence of pre-malignancy or malignancy in polyps as dependent variables. A 10-fold cross-validation method was used to estimate the model’s misclassification risk. Results: There were 240 women included, 181 of whom presented with postmenopausal bleeding. Their median age was 60 (range of 45–94); 18/240 (7.5%) women were diagnosed with pre-malignant or malignant polyps. In our decision tree model, the polyp mean diameter (≤13 mm or >13 mm) on ultrasound was the most important predictor of pre-malignancy or malignancy. If the tree was allowed to grow, the patient’s body mass index (BMI) and cystic/solid appearance of the polyp classified women further into low-risk (≤5%), intermediate-risk (>5%–≤20%), or high-risk (>20%) groups. Conclusions: Our decision tree model may serve as a guide to counsel women on the benefits and risks of surgery for postmenopausal endometrial polyps. It may also assist clinicians in prioritizing women for surgery according to their risk of malignancy.


2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Zhong Xin ◽  
Lin Hua ◽  
Xu-Hong Wang ◽  
Dong Zhao ◽  
Cai-Guo Yu ◽  
...  

We reanalyzed previous data to develop a more simplified decision tree model as a screening tool for unrecognized diabetes, using basic information in Beijing community health records. Then, the model was validated in another rural town. Only three non-laboratory-based risk factors (age, BMI, and presence of hypertension) with fewer branches were used in the new model. The sensitivity, specificity, positive predictive value, negative predictive value, and area under the curve (AUC) for detecting diabetes were calculated. The AUC values in internal and external validation groups were 0.708 and 0.629, respectively. Subjects with high risk of diabetes had significantly higher HOMA-IR, but no significant difference in HOMA-B was observed. This simple tool will help general practitioners and residents assess the risk of diabetes quickly and easily. This study also validates the strong associations of insulin resistance and early stage of diabetes, suggesting that more attention should be paid to the current model in rural Chinese adult populations.


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