scholarly journals Financial burden impact quality of life among Lymphatic Filariasis Patients

2020 ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Alexander Kwarteng ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
P Value ◽  
Life Questionnaire ◽  
Financial Condition ◽  
Severity Of The Disease ◽  
Study Participants

Abstract Background: Human lymphatic filarial pathology is the main cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the morbidity associated with the disease with the purpose of improving the quality of life of the patients. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana. Method: In the present study, the Lymphatic Filariasis Quality of Life Questionnaire (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people, with the disease in nine (9) communities in the Ahanta West District of the Western Region of Ghana where mass drug administration is being implemented for the past twenty years. Pearson’s correlation, linear regression and one-way analysis of variance (ANOVA) analyses were used to assess the associations between the domains of LFSQQ instrument. Results: Of the 155 study participants recruited, 115 (74.19%) were females and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphedema while only 2 patients had stage seven (7) lymphedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = -0.504, p-value < 0.001) between the stage of lymphedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas the highest domain specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consists of the financial status was the lowest (45.94) among the study participants. Conclusion: Our findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their wellbeing.

scholarly journals Financial burden impact quality of life among Lymphatic Filariasis Patients

2020 ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Alexander Kwarteng ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
P Value ◽  
Life Questionnaire ◽  
Financial Condition ◽  
Severity Of The Disease ◽  
Study Participants

Abstract Background Human lymphatic filarial pathology is the main cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the morbidity associated with the disease with the purpose of improving the quality of life of the patients. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana. Method In the present study, the Lymphatic Filariasis Quality of Life Questionnaire (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people, with the disease in nine (9) communities in the Ahanta West District of the Western Region of Ghana where mass drug administration is being implemented for the past twenty years. Pearson’s correlation, linear regression and one-way analysis of variance (ANOVA) analyses were used to assess the associations between the domains of LFSQQ instrument. Results Of the 155 study participants recruited, 115 (74.19%) were females and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphedema while only 2 patients had stage seven (7) lymphedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = -0.504, p-value < 0.001) between the stage of lymphedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas the highest domain specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consists of the financial status was the lowest (45.94) among the study participants. Conclusion Our findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their wellbeing.

scholarly journals Financial burden impact quality of life among Filarial Pathology Patients

2020 ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Alexander Kwarteng ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
P Value ◽  
Life Questionnaire ◽  
Financial Condition ◽  
Severity Of The Disease ◽  
Study Participants

Abstract Background Human lymphatic filarial pathology is the main cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the morbidity associated with the disease with the purpose of improving the quality of life of the patients. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana. Method In the present study, the Lymphatic Filariasis Quality of Life Questionnaire (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people, with the disease in nine (9) communities in the Ahanta West District of the Western Region of Ghana where mass drug administration is being implemented for the past twenty years. Pearson’s correlation, linear regression and one-way analysis of variance (ANOVA) analyses were used to assess the associations between the domains of LFSQQ instrument.Results Of the 155 study participants recruited, 115 (74.19%) were females and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphedema while only 2 patients had stage seven (7) lymphedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = -0.504, p-value < 0.001) between the stage of lymphedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas the highest domain specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consists of the financial status was the lowest (45.94) among the study participants. Conclusion Our findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their wellbeing.

scholarly journals Financial burden impact quality of life among Lymphatic Filariasis Patients

2021 ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Alexander Kwarteng ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
Well Being ◽  
P Value ◽  
Life Questionnaire ◽  
Financial Condition ◽  
Study Participants

Abstract BackgroundHuman lymphatic filarial pathology is the leading cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the disease's morbidity to improve patients' quality of life. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana. MethodIn the present study, the Lymphatic Filariasis Quality of Life Questionnaire (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people, with the disease in nine (9) communities in the Ahanta West District of the Western Region of Ghana where mass drug administration is being implemented for the past twenty years. Pearson’s correlation, linear regression, and one-way analysis of variance (ANOVA) analyses were used to assess the associations between the LFSQQ instrument domains.ResultsOf the 155 study participants recruited, 115 (74.19%) were females, and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphoedema, while only two patients had stage seven (7) lymphoedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = -0.504, p-value < 0.001) between the stage of lymphoedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas the highest domain-specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consists of the financial status, was the lowest (45.94) among the study participants. ConclusionOur findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their well-being.

scholarly journals Financial burden impact quality of life among lymphatic Filariasis patients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Alexander Kwarteng ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
Well Being ◽  
Life Questionnaire ◽  
Financial Condition ◽  
Severity Of The Disease ◽  
Study Participants

Abstract Background Human lymphatic filarial pathology is the leading cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the disease’s morbidity to improve patients’ quality of life. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana. Method In the present study, the Lymphatic Filariasis Quality of Life Questionnaire (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people, with the disease in nine (9) communities in the Ahanta West District of the Western Region of Ghana where mass drug administration is being implemented for the past twenty years. Pearson’s correlation, linear regression, and one-way analysis of variance (ANOVA) analyses were used to assess the associations between the LFSQQ instrument domains. Results Of the 155 study participants recruited, 115 (74.19%) were females, and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphoedema, while only two patients had stage seven (7) lymphoedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = − 0.504, p-value < 0.001) between the stage of lymphoedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas the highest domain-specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consists of the financial status, was the lowest (45.94) among the study participants. Conclusion Our findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their well-being.

scholarly journals Financial burden reportedly impact quality of life among Lymphatic Filariasis Pathology Patients in Ghana

2020 ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
John Boulard Forkuor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
P Value ◽  
Domain Specific ◽  
Financial Condition ◽  
Severity Of The Disease ◽  
Study Participants

Abstract BackgroundHuman lymphatic filarial pathology is the main cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the morbidity associated with the disease with the purpose of improving the quality of life of the patients. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana.MethodIn the present study, the Lymphatic Filariasis Quality of Life Questionnaires (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people with the disease in ten (10) communities in the Ahanta West District of the Western Region of Ghana where, mass drug administration is being implemented for the past twenty years.ResultsOf the 155 study participants recruited, 115 (74.19%) were females and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphedema while only 2 patients had stage seven (7) lymphedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = -0.504, p-value < 0.0001) between the stage of lymphedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas, the highest domain specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consist of the financial status was the lowest (45.94) among the study participants.ConclusionOur findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their wellbeing.

scholarly journals Financial Burden Reportedly Impact Quality of Life Among Lymphatic Filariasis Pathology Patients in Ghana

2020 ◽  
Author(s):  
Samuel Opoku Asiedu ◽  
Emmanuel Kobla Atsu Amewu ◽  
Priscilla Kini ◽  
Bill Clinton Aglomasa ◽  
John Boulard Forkuor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lymphatic Filariasis ◽  
Financial Burden ◽  
Pearson Correlation ◽  
P Value ◽  
Domain Specific ◽  
Financial Condition ◽  
Severity Of The Disease ◽  
Study Participants

Abstract BackgroundHuman lymphatic filarial pathology is the main cause of disability and poverty among people living with the infection. The second goal of the Global Programme to Eliminate Lymphatic Filariasis (GPELF) is to manage the morbidity associated with the disease with the purpose of improving the quality of life of the patients. Consequently, the current study assessed the overall quality of life of lymphatic filariasis (LF) pathology patients in some selected endemic communities in rural Ghana. MethodIn the present study, the Lymphatic Filariasis Quality of Life Questionnaires (LFSQQ) was used to evaluate the effect of lymphatic filariasis on the quality of life of people with the disease in ten (10) communities in the Ahanta West District of the Western Region of Ghana where, mass drug administration is being implemented for the past twenty years. ResultsOf the 155 study participants recruited, 115 (74.19%) were females and 40 (25.81%) males. A greater proportion of the study participants (40, 25.8%) were presented with stage two (2) lymphedema while only 2 patients had stage seven (7) lymphedema. The average of the overall quality of life scores of study participants was 68.24. There was a negative Pearson correlation (r = -0.504, p-value < 0.0001) between the stage of lymphedema (severity of the disease) and the quality of life of the LF patients. In addition, a clear pattern of positive correlation (r = 0.71, p-value < 0.001) was observed between the disease burden and pain/discomfort domains of the study participants. Whereas, the highest domain specific score (85.03) was observed in the domain of self-care, we noted that the environmental domain, which consist of the financial status was the lowest (45.94) among the study participants. ConclusionOur findings support previous works on the reduced quality of life among lymphatic filariasis patients with pathology. In this study, our results reveal a depressing financial condition among people presenting with late stages of LF pathologies, which eventually reduces their wellbeing.

scholarly journals QUALIDADE DE VIDA NO TRABALHO DA EQUIPE DE ENFERMAGEM DO CENTRO CIRÚRGICO

2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Arethuza De Melo Brito Carvalho ◽  
Juliana Araújo Cardoso ◽  
Francisca Aline Amaral Da Silva ◽  
Jefferson Abraão Caetano Lira ◽  
Samuel Moura Carvalho
Keyword(s):  
Quality Of Life ◽  
Family Income ◽  
Pearson Correlation ◽  
Working Life ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Calidad De Vida ◽  
Kolmogorov Smirnov ◽  
Room Nursing

Objetivo: avaliar a qualidade de vida no trabalho da equipe de enfermagem do centro cirúrgico. Metodologia: estudo descritivo, de corte transversal e com abordagem quantitativa, desenvolvido com 70 profissionais de enfermagem do centro cirúrgico em um hospital de referência em Teresina (PI), com a aplicação dos questionários sociodemográfico e Quality Working Life Questionnaire-bref. A análise foi realizada com o SPSS versão 21.0, utilizando a correlação de Pearson e os testes alfa de Cronbach, Kolmogorov-Smirnov, Qui-quadrado e regressão linear múltipla, com intervalo de confiança de 95%. Resultados: a maioria dos participantes (62,9%) tiveram menor impacto na qualidade de vida no trabalho, entretanto a renda familiar e a formação acadêmica foram bastante significativas. Conclusão: apesar do trabalho no centro cirúrgico apresentar baixo impacto na qualidade de vida, o domínio psicológico demonstrou impacto considerável, destacando que a preocupação com a saúde do trabalhador e a valorização da equipe de enfermagem ainda precisam avançar.Descritores: Qualidade de vida; Enfermagem de centro cirúrgico; Saúde do trabalhador.QUALITY OF LIFE IN THE WORK OF THE SURGI CAL CENTER NURSING TEAMObjective: to evaluate the quality of life in the work of the nursing staff of the surgical center. Methodology: a descriptive, cross-sectional study with a quantitative approach developed with 70 nursing professionals from a surgical center at a reference hospital in Teresina (PI), with the application of the sociodemographic and Quality Working Life Questionnairebref questionnaires. The analysis was performed with the SPSS version 21.0, using the Pearson correlation and the Cronbach, Kolmogorov-Smirnov, Chi-square and multiple linear regression alpha tests with a 95% confidence interval. Results: the majority of the participants (62.9%) had a lower impact on the quality of life at work, however the family income and academic training were quite significant. Conclusion: Although the work in the surgical center has a low impact on the quality of life, the psychological domain has shown considerable impact, emphasizing that the concern with the health of the worker and the appreciation of the nursing team still need to move forward.Descriptors: Quality of life; Operating Room Nursing; Occupational Health.CALIDAD DE VIDA EN ENFERMERÍA DEL CENTRO DE TRABA JO DE EQUIPO QUIRÚRGICOObjetivo: Evaluar la calidad de vida del personal de enfermería que trabaja en la sala de operaciones. Metodología: enfoque descriptivo, transversal y cuantitativo desarrollado con 70 enfermeras en el quirófano de un hospital de referencia en Teresina (PI), con la aplicación de un cuestionario sociodemográfico y Calidad de Vida Cuestionario de Trabajo-BREF. El análisis se realizó con el programa SPSS versión 21.0 mediante la prueba de correlación de Pearson y alfa de Cronbach, prueba de Kolmogorov-Smirnov, regresión lineal chi-cuadrado y múltiple con un intervalo de confianza del 95%. Resultados: La mayoría de los participantes (62,9%) tenían un menor impacto en la calidad de la vida laboral, aunque el ingreso familiar y la formación académica eran bastante significativa. Conclusión: Aunque el trabajo en la sala de operaciones tiene un bajo impacto en la calidad de vida, el dominio psicológico mostró un impacto considerable, teniendo en cuenta que la preocupación por la salud de los trabajadores y la apreciación del equipo de enfermería todavía tienen que seguir adelante.Descriptores: Calidad de vida; Enfermería de quirófano; Salud laboral.

scholarly journals Assessment of quality of life in asthma patients in 5 to 18 years of children

2020 ◽  
Vol 7 (11) ◽  
pp. 2214
Author(s):  
Nikhil Jain ◽  
Karan Joshi
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Persistent Asthma ◽  
Tertiary Hospital ◽  
P Value ◽  
Cross Sectional ◽  
Asthmatic Patients ◽  
Asthma Patients ◽  
Severity Of The Disease

Background: Asthma is a common cause of morbidity and mortality with prevalence of 300 million in world. The QOL of asthmatic patients cannot be determined only on the basis the severity of the disease, but requires a measurement of personal perception. This study was conducted with the aim to assess and compare the QOL using PedsQl scale in asthma patients between 5 to 18 years of age with different demographic and clinical variables.Methods: This was a cross-sectional observational study conducted at respiratory clinic in tertiary hospital, Rewa from October 2017 to June 2019. A total number of 150 asthmatic patients and their parents participated. Asthmatic patients (N=150) and their parents, presenting to asthma clinic of Gandhi Memorial Hospital, Rewa (after applying inclusion-exclusion criteria) were assessed for QOL using PedsQl scale 3.0. Statistical analysis was performed by SPSS version 20. Test of significance by student T-test and one way ANOVA.Results: The QOL is severely hampered by asthma with mean of 59 in intermittent asthma, 51 in mild, 44.74 in moderate and 40 in severe persistent asthma, significant p value of <0.05. Younger age, level of asthma control and severity were significantly related to QOL with p value of <0.05. Sex, socioeconomic status, were insignificantly related.Conclusions: QOL is impaired as the grading of asthma increases. Impairment of Quality of life are mostly associated with low level of asthma control, poly-therapy and frequent night attacks.

scholarly journals Association of physical activity and quality of life among cancer patients

2021 ◽  
Vol 8 (06) ◽  
pp. 5463-5468
Author(s):  
Ruchika Kalra ◽  
Bhavna Anand ◽  
Shubh Shree ◽  
Himani Chauhan ◽  
Harshita Sharma
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Cancer Patients ◽  
Pearson Correlation ◽  
Genetic Mutation ◽  
Life Questionnaire ◽  
Data Collection And Analysis ◽  
Lifestyle Diseases ◽  
The Relationship

Background: Cancer is one of the lifestyle diseases which in years have multiplied the patients into numbers in every country and on the graph in inclination depending on the factors of our lifestyle and genetic mutation leading to this disease. Studies have proved that effect of cancer is more on the quality of life for the patient in all aspects of his or her life. Objectives: The objective of the study was to find the relationship between quality of life and physical activity in the cancer patients. Search Methods: Survey questionnaire was given by google forms where the Quality-of-life questionnaire with the FACT- G form for physical activity. Selection criteria:  The criteria were males and females of 40 years and above patients with the cancer in any stage and able to understand English. Data collection and analysis: There were 63 patients as sample for study, proceeded with the consent of 40 years and above with different types and stages of cancers. The analysis created the relation of cancer to depending upon the stage of it and associating the physical activity with quality of life. Main Results: The statistical analytical tool for finding correlation was Pearson correlation coefficient creating labelling the QOL at X value and FACT-G at Y value creating the positive correlation in the study with the value of is 0.7563. Authors’ conclusions:  Authors came with the conclusion that there is correlation between quality of life and physical activity and are directly proportional as one value decrease so as in other and vice-versa.

scholarly journals Validating an Instrument for Direct Patient Reporting of Distress and Chemotherapy-Related Toxicity among South African Cancer Patients

Cancers ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 95
Author(s):  
Charmaine L. Blanchard ◽  
Keletso Mmoledi ◽  
Michael H. Antoni ◽  
Georgia Demetriou ◽  
Maureen Joffe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Construct Validity ◽  
Cancer Patients ◽  
South African ◽  
Pearson Correlation ◽  
Performance Status ◽  
Summary Score ◽  
Life Questionnaire ◽  
Patient Reported

Patient-reported outcome measures (PROM) for monitoring treatment toxicity improve quality of life (QoL) and clinical outcomes. However, no such PROMs exist for sub-Saharan African cancer patients. We aimed to validate the Patient Reported Symptoms-South Africa (PRS-SA) survey, a novel PROM for measuring distress and chemotherapy-related symptoms in South African cancer patients. We enrolled patients at the oncology clinic at Charlotte Maxeke Hospital, Johannesburg. At three separate visits, participants simultaneously completed the PRS-SA survey and several previously validated questionnaires. We constructed a receiver operator characteristics curve for distress levels predicting a Hospital Anxiety and Depression Scale (HADS) score ≥15. We evaluated construct validity for symptom items by comparing severity to the EORTC Core Quality of Life Questionnaire (QLQ-C30) summary score (Pearson correlation tests) and ECOG performance status (Mann–Whitney U tests). We assessed symptom item responsiveness by comparing change in severity to change in QLQ-C30 summary score and comparing standardized mean scores with negative, no, or positive change on the Global Impression of Change (GIC) questionnaire (Jockheere–Terpstra trend test). Overall, 196 participants with solid tumors completed instruments. A distress score of 4 had 82% sensitivity and 55% specificity for clinical depression/anxiety. All symptom items showed construct validity by association with either QLQ-C30 score or performance status (highest p = 0.03). All but cough showed responsiveness to change in QLQ-C30 score (highest p = 0.045). In South African cancer patients, the PRS-SA’s stress scale behaves similarly to the distress thermometer in other populations, and the symptom items demonstrated construct validity and responsiveness. Of note, 46% and 74% of participants who completed the PRS-SA in English or isiZulu, respectively, required assistance reading half or more of the instrument.

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