scholarly journals A New Threshold Reveals The Uncertainty About The Effect of School Opening On Diffusion of Covid-19.

Author(s):  
Alberto Gandolfi ◽  
Andrea Aspri ◽  
Elena Beretta ◽  
Khola Jamshad ◽  
Muyan Jiang

Abstract We aim at clarifying the controversy about the effects of school openings or closures on the course of the Covid-19 pandemic.The mathematical analysis of compartmental models with subpopulations shows that the in-school contact rates affects the overall course of the pandemic only above a certain threshold that separates an influence phase from a non-influence one. The threshold, that we calculate via linear approximation in several cases, seems to appear in all contexts, including outbreaks or new strains upsurge, lockdowns, and vaccination campaigns excluding children, albeit with different values. Our theoretical findings are then confirmed by several data driven studies that have previously identified the phase transition in specific cases.Specific outcomes of this study are:• opposite conclusions reached by studies of the same or similar situations might depend on, possibly small, differences in modeling or in parameter estimation from the very noisy Covid-19 data, that result in identifying different phases;• it is possible to keep schools open at any stage of the Covid-19 pandemic, but suitably strict rules must be applied at all times or else this becomes highly detrimental to virus containment efforts;• as the threshold during vaccination turns out to correspond to the internal transmission rate that would lead to virus extinction if the school population was isolated, the needed strict control can be sustained only for very brief periods; as a result, either schools will have to face a prolonged closure or children need to be vaccinated as well.

BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
James D. Munday ◽  
Christopher I. Jarvis ◽  
Amy Gimma ◽  
Kerry L. M. Wong ◽  
Kevin van Zandvoort ◽  
...  

Abstract Background Schools were closed in England on 4 January 2021 as part of increased national restrictions to curb transmission of SARS-CoV-2. The UK government reopened schools on 8 March. Although there was evidence of lower individual-level transmission risk amongst children compared to adults, the combined effects of this with increased contact rates in school settings and the resulting impact on the overall transmission rate in the population were not clear. Methods We measured social contacts of > 5000 participants weekly from March 2020, including periods when schools were both open and closed, amongst other restrictions. We combined these data with estimates of the susceptibility and infectiousness of children compared with adults to estimate the impact of reopening schools on the reproduction number. Results Our analysis indicates that reopening all schools under the same measures as previous periods that combined lockdown with face-to-face schooling would be likely to increase the reproduction number substantially. Assuming a baseline of 0.8, we estimated a likely increase to between 1.0 and 1.5 with the reopening of all schools or to between 0.9 and 1.2 reopening primary or secondary schools alone. Conclusion Our results suggest that reopening schools would likely halt the fall in cases observed between January and March 2021 and would risk a return to rising infections, but these estimates relied heavily on the latest estimates or reproduction number and the validity of the susceptibility and infectiousness profiles we used at the time of reopening.


Author(s):  
Tushar ◽  
Shikhar Pandey ◽  
Anurag K. Srivastava ◽  
Penn Markham ◽  
Navin Bhatt ◽  
...  

Author(s):  
Claudio Cobelli ◽  
David Foster ◽  
Gianna Toffolo

2019 ◽  
Vol 467 ◽  
pp. 87-99 ◽  
Author(s):  
Karen Larson ◽  
Loukas Zagkos ◽  
Mark Mc Auley ◽  
Jason Roberts ◽  
Nikos I. Kavallaris ◽  
...  

2020 ◽  
Vol 101 (20) ◽  
Author(s):  
Sergey S. Krishtopenko ◽  
Mauro Antezza ◽  
Frédéric Teppe

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