scholarly journals Enlightenment for Clinicians From the Case of Digestive Tract Metastases From Primary Lung Cancer: a Case Report

Author(s):  
Shaochun Wang ◽  
Shuili Wang ◽  
Wei Zhang ◽  
Yeqin Zhang

Abstract Background: About 50% of patients with initially diagnosed lung cancer have developed distant metastasis. The probability of occurrence of digestive tract metastases found by autopsy is rarely. This report presents a rare clinical case of small intestinal metastasis from primary squamous cell carcinoma of the lung. Case presentation: An 82-year-old male with aggravated cough and more acute shortness of breath than usual was diagnosed with primary squamous cell carcinoma of the lung Stage IV, because of the advanced age, underlying diseases, and poor cardiopulmonary function,the family refused the chemoradiotherapy.One month later, the patient gradually developed right lower quadrant pain. An upright abdominal X-ray suggested small intestinal obstruction and partial resection and anastomosis of the small intestine were performed. Postoperative pathology revealed poorly differentiated squamous-cell carcinoma of the small intestine. The patient died of sudden cardio-respiratory arrest one month later. Conclusions: We conclude that the real incidence of digestive tract metastases from lung cancer may be higher than the reported because of the symptoms of those patients are not obvious. Clinicians should select the appropriate examination methods (such as positron emission tomography) and pay attention to the assessment of abdominal hollow organs.

2003 ◽  
Vol 10 (8) ◽  
pp. 435-441 ◽  
Author(s):  
Sandor J Demeter ◽  
Chester Chmielowiec ◽  
Wayne Logus ◽  
Pauline Benkovska-Angelova ◽  
Philip Jacobs ◽  
...  

BACKGROUND: Lung cancer contributes significantly to cancer morbidity and mortality. Although case fatality rates have not changed significantly over the past few decades, there have been advances in the diagnosis, staging and management of lung cancer.OBJECTIVE: To describe the epidemiology of primary lung cancer in an Alberta cohort with an analysis of factors contributing to survival to two years.PATIENTS AND METHODS: Six hundred eleven Albertans diagnosed with primary lung cancer in 1998 were identified through the Alberta Cancer Registry. Through a chart review, demographic and clinical data were collected for a period of up to two years from the date of diagnosis.RESULTS: The mean age at diagnosis was 66.5 years. The majority of cases (92%) were smokers. Adenocarcinoma, followed by squamous cell carcinoma, were the most frequent nonsmall cell lung cancer histologies. Adenocarcinoma was more frequent in women, and squamous cell carcinoma was more frequent in men. The overall two- year survival rates for nonsmall cell, small cell and other lung cancers were 24%, 10% and 13%, respectively. In multivariate analysis, stage, thoracic surgery and chemotherapy were significantly associated with survival to two years in nonsmall cell carcinoma; only stage and chemotherapy were significant in small cell carcinoma.CONCLUSIONS: This study provides a Canadian epidemiological perspective, which generally concurs with the North American literature. Continued monitoring of the epidemiology of lung cancer is essential to evaluate the impact of advances in the diagnosis, staging and management of lung cancer. Further clinical and economic analysis, based on data collected on this cohort, is planned.


Haigan ◽  
1990 ◽  
Vol 30 (1) ◽  
pp. 93-97
Author(s):  
Noriaki Tsubota ◽  
Takesi Hatta ◽  
Yosiki Takata ◽  
Kayoko Obayasi ◽  
Isamu Narabayasi ◽  
...  

Haigan ◽  
1989 ◽  
Vol 29 (7) ◽  
pp. 737-745
Author(s):  
Shinobu Hatakeyama ◽  
Akihiko Nagai ◽  
Yoshiaki Nakajima ◽  
Satoru Kioi ◽  
Masaaki Arakawa

2013 ◽  
Vol 9 (4) ◽  
pp. 739
Author(s):  
ShirishS Nandedkar ◽  
KarunakarK Trivedi ◽  
Kamal Malukani

2011 ◽  
Vol 96 (2) ◽  
pp. 176-181 ◽  
Author(s):  
Hideki Yamada ◽  
Takuya Akahane ◽  
Atsushi Horiuchi ◽  
Ryu Shimada ◽  
Hajime Shibuya ◽  
...  

Abstract Gastrointestinal metastasis of lung cancer is fairly rare, and metastasis to the duodenum is very uncommon. We report a case of duodenum and small intestine metastases of lung squamous cell carcinoma. The patient was a 66-year-old man. He was diagnosed with lung squamous cell carcinoma (T4N3M1 [mediastinum, cervical lymph node, and duodenum metastases], stage IV). He noted a sense of abdominal fullness on the evening of the day chemoradiotherapy was given, and emergency surgery was performed for suspected perforation of the digestive tract. Intraoperative findings included a tumor in the small intestine with a perforation at the tumor site; partial resection of the small intestine, including the tumor, was performed. Small intestine metastasis of lung cancer was diagnosed following histopathologic examination. When lung cancer patients complain of abdominal symptoms, it is important to consider gastrointestinal metastases in diagnosis and treatment.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yi Yuan ◽  
Hong Pu ◽  
Ming-hui Pang ◽  
Yi-sha Liu ◽  
Hang Li

Abstract Background Thymic carcinoma is a rare mediastinal neoplasm with a high malignant potential. It often shows pleural invasion and distant metastasis. The metastasis of thymic carcinoma to the small intestine is rarely reported and difficult to distinguish from other gastrointestinal tract tumors. Case presentation An elderly man presented with lower abdominal pain for 2 months. Abdominal CT showed a mass communicated with the small intestinal lumen. After radical resection of the small intestinal tumor, resected specimens showed moderately differentiated squamous-cell carcinoma with lymph nodes metastases. The patient received chest CT and was found to have a mass in anterior mediastinum. Biopsies of the mass revealed thymic squamous-cell carcinoma. Conclusions We highlighted the metastasis of thymic carcinoma to the small intestine is rare and easily misdiagnosed. In patients with a mass communicated with the small intestinal lumen, a suspicion of thymic carcinoma metastasis should not be overlooked and we should make accurate differential diagnosis from the other small intestinal tumors.


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