Prevalence and Risk Factors of Preoperative Frailty in Chinese Elderly Inpatients with Gastrointestinal Cancer Undergoing Surgery: A Single-center Cross-sectional Study Using the Groningen Frailty Indicator

2021 ◽  
Author(s):  
Qianqian Zhang ◽  
Meng Zhang ◽  
Shaohua Hu ◽  
Lei Meng ◽  
Jing Xi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Cancer ◽  
Handgrip Strength ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Groningen Frailty Indicator ◽  
Elderly Inpatients ◽  
Frailty Indicator

Abstract BackgroundFrailty is emerging as an important determinant for health. Compared with Western countries, research in the field of frailty started at a later stage in China and mainly focused on older community dwellers. Little is known about frailty in Chinese cancer patients, nor the risk factors of frailty. This study aimed to investigate the prevalence of frailty and its risk factors in elderly inpatients with gastrointestinal cancer. MethodsThis cross-sectional study was performed at a tertiary hospital in China from Mar. 2020 to Nov. 2020. The study enrolled 265 inpatients aged 60 and older with gastrointestinal cancer who underwent surgery. The demographic and clinical characteristics, biochemical laboratory parameters, and anthropometric data were collected from all patients. The Groningen Frailty Indicator was applied to assess the frailty status of patients. Multivariate logistic regression model analysis was carried out to identify risk factors of frailty and estimate their 95% confidence intervals. ResultsThe prevalence of frailty in elderly inpatients with gastrointestinal cancer was 43.8%. A multivariate logistic regression analysis showed that older age (OR=1.065, 95% CI: 1.001-1.132, P=0.045), low handgrip strength (OR=4.346, 95% CI: 1.739-10.863, P=0.002), no regular exercise habit (OR=3.228, 95% CI: 1.230-8.469, P=0.017), and low MNA-SF score (OR=11.090, 95% CI: 5.119-24.024, P<0.001) were risk factors of frailty. ConclusionsThis study suggested that the prevalence of frailty was high among elderly inpatients with gastrointestinal cancer. Older age, low handgrip strength, no regular exercise habit, and low MNA-SF score were identified as risk factors of frailty.

scholarly journals Burden of stillbirths and associated factors in Yirgalem Hospital, Southern Ethiopia: a facility based cross-sectional study

2020 ◽  
Author(s):  
Sintayehu Mengesha ◽  
Mesay Hailu Dangisso
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Prolonged Labour ◽  
Tailored Interventions

Abstract Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden on parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia. Methods: A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of pregnant women from a hospital delivery registry. Bivariate analysis was employed to assess the association between independent and dependent variables using chi-square with significant p-value. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding variables.Results: Of 374 reviewed records of pregnant women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Fifteen (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (<2500grams) (adjusted odds ratio (AOR): 10.70, 95% CI 3.18-35.97) than normal birth-weight babies (2500-<4000). Pregnant women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76-84.12) more likely to have stillbirths than pregnant women without a prolonged labour. Pregnant women with obstetric complications were 18.9 times more likely to have stillbirths than pregnant women without obstetric complications. Similarly, pregnant women with at least two pregnancies were more likely to have stillbirths than pregnant women with less than two pregnancies (AOR: 4.39, 95% CI 1.21-15.85).Conclusion: We found a high burden of stillbirths in the study setting. Modifiable risk factors contributed to a higher risk of stillbirths; therefore, tailored interventions such as early identification and management of prolonged labour and obstetric complication at each level of health system could avert preventable stillbirths.

Prevalence and Risk Factors of Frailty in a Community-Dwelling Population: The HELIAD Study

2018 ◽  
Vol 32 (1-2) ◽  
pp. 14-24 ◽  
Author(s):  
E. Ntanasi ◽  
M. Yannakoulia ◽  
N. Mourtzi ◽  
G. S. Vlachos ◽  
M. H. Kosmidis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Population Studies ◽  
Frailty Index ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tilburg Frailty Indicator ◽  
Frailty Indicator

Objective: To estimate the prevalence of frailty using five different instruments in a cohort of older adults and explore the association between frailty and various risk factors. Method: 1,867 participants aged 65 years and above were included in the current retrospective cross-sectional study. Frailty was operationalized according to the Fried definition, the FRAIL Scale, the Frailty Index (FI), the Tilburg Frailty Indicator (TFI), and the Groningen Frailty Index (GFI). We explored the role of various frailty risk factors using logistic regression analyses. Results: The prevalence of frailty varied depending on the definition used (Fried definition = 4.1%, FRAIL Scale = 1.5%, FI = 19.7%, TFI = 24.5%, and GFI = 30.2%). The only risk factors consistently associated with frailty irrespectively of definition were education and age. Conclusion: The frailty prevalence reported in our study is similar or lower to that reported in other population studies. Qualitative differences between frailty definitions were observed.

scholarly journals Burden of stillbirths and associated factors in Yirgalem Hospital, Southern Ethiopia: a facility based cross-sectional study

2020 ◽  
Author(s):  
Sintayehu Mengesha ◽  
Mesay Hailu Dangisso
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Prolonged Labour ◽  
Tailored Interventions

Abstract Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden on parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia. Methods: A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of pregnant women from a hospital delivery registry. Bivariate analysis was employed to assess the association between independent and dependent variables using chi-square with significant p-value. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding variables.Results: Of 374 reviewed records of pregnant women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Fifteen (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (<2500grams) (adjusted odds ratio (AOR): 10.70, 95% CI 3.18-35.97) than normal birth-weight babies (2500-<4000). Pregnant women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76-84.12) more likely to have stillbirths than pregnant women without a prolonged labour. Pregnant women with obstetric complications were 19.8 times more likely to have stillbirths than pregnant women without obstetric complications. Similarly, pregnant women with at least two pregnancies were more likely to have stillbirths than pregnant women with less than two pregnancies (AOR: 4.39, 95% CI 1.21-15.85).Conclusion: We found a high burden of stillbirths in the study setting. Modifiable risk factors contributed to a higher risk of stillbirths; therefore, tailored interventions such as early identification and management of prolonged labour and obstetric complication at each level of health system could avert preventable stillbirths.

scholarly journals Burden of stillbirths and associated factors in Yirgalem Hospital, Southern Ethiopia: a facility based cross-sectional study

2020 ◽  
Author(s):  
Sintayehu Mengesha ◽  
Mesay Hailu Dangisso
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Prolonged Labour ◽  
Tailored Interventions

Abstract Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden for parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia Methods : A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of pregnant women from a hospital delivery registry. Bivariate analysis was employed to assess the association between independent and dependent variables using chi-square with significant p-value. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding.. Results : Of 374 reviewed records of pregnant women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Fifteen, 15 (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (<2500grams) (adjusted odds ratio (AOR): 10.70, 95% CI 3.18-35.97) than normal birth-weight babies (2500-<4000). Pregnant women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76-84.12) more likely to have stillbirths than pregnant women without a prolonged labour. Pregnant women with obstetric complications were 19.8 times more likely to have stillbirths than pregnant women without obstetric complications. Similarly, pregnant women with at least 2 pregnancies were more likely to have stillbirths than pregnant women with less than two pregnancies (AOR: 4.39, 95% CI 1.21-15.85). Conclusion: We found a high burden of stillbirths in the study setting. Modifiable risk factors contributed to a higher risk of stillbirths; therefore, tailored interventions such as early identification and management of prolonged labour and obstetric complication at each level of health system could avert preventable stillbirths.

scholarly journals Identifying frailty: do the Frailty Index and Groningen Frailty Indicator cover different clinical perspectives? a cross-sectional study

2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Irene Drubbel ◽  
Nienke Bleijenberg ◽  
Guido Kranenburg ◽  
René JC Eijkemans ◽  
Marieke J Schuurmans ◽  
...  
Keyword(s):  
Frailty Index ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Groningen Frailty Indicator ◽  
Frailty Indicator

scholarly journals Burden of stillbirths and associated factors in Yirgalem Hospital, Southern Ethiopia: a facility based cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sintayehu Mengesha ◽  
Mesay Hailu Dangisso
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Prolonged Labour ◽  
Tailored Interventions

Abstract Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden on parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia. Methods A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of pregnant women from a hospital delivery registry. Bivariate analysis was employed to assess the association between independent and dependent variables using chi-square with significant p-value. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding variables. Results Of 374 reviewed records of pregnant women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Fifteen (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (< 2500grams) (adjusted odds ratio (AOR): 10.70, 95% CI 3.18–35.97) than normal birth-weight babies (2500-<4000). Pregnant women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76–84.12) more likely to have stillbirths than pregnant women without a prolonged labour. Pregnant women with obstetric complications were 18.9 times more likely to have stillbirths than pregnant women without obstetric complications. Similarly, pregnant women with at least two pregnancies were more likely to have stillbirths than pregnant women with less than two pregnancies (AOR: 4.39, 95% CI 1.21–15.85). Conclusions We found a high burden of stillbirths in the study setting. Modifiable risk factors contributed to a higher risk of stillbirths; therefore, tailored interventions such as early identification and management of prolonged labour and obstetric complication at each level of health system could avert preventable stillbirths.

scholarly journals Burden of stillbirths and associated factors in Yirgalem Hospital, Southern Ethiopia: a facility based cross-sectional study

2019 ◽  
Author(s):  
Sintayehu Mengesha ◽  
Mesay Hailu Dangisso
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Birth Weight ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Southern Ethiopia ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Prolonged Labour

Abstract Abstract Background Stillbirth is an adverse pregnancy outcome of public health importance causing considerable psychosocial burden for parents and their family. Studies on stillbirth are scarce in southern Ethiopia. An assessment of stillbirths and associated factors in health care settings helps in devising strategies for tailored interventions. Therefore, we assessed the burden of stillbirths and associated factors in Yirgalem Hospital, southern Ethiopia Methods: A facility based cross-sectional study was conducted between 1 August 2015 and 30 July 2016. We randomly selected medical records of women from a hospital delivery registry. The data were coded, entered, cleaned, and analysed by SPSS version 20. Bivariate analysis was employed to assess the association between independent and dependent variables. Multivariate logistic regression was used to identify independent risk factors for stillbirths and to control for confounding. The ethical clearance for the study was obtained from the Institutional Review Board of College of Medicine and Health Sciences, Hawassa University. Results: Of 374 reviewed records of women, 370 were included for the study. The magnitude of stillbirths was 92 per 1000 births. Majority, 15 (44.1%) of fetal deaths occurred after admission to the hospital. In multivariate logistic regression, stillbirths were higher among low birth-weight babies (<2500grams) (AOR: 10.70, 95% CI 3.18-35.97) than normal birth-weight babies (2500-<4000). Women who experienced a prolonged labour for more than 48 hours were 12 times (AOR: 12.15, 95% CI 1.76-84.12) more likely to have stillbirths than women without a prolonged labour. Women with obstetric complications were 19.8 times more likely to have stillbirths than women without obstetric complications. Similarly, women with at least 2 pregnancies were more likely to have stillbirths than women with less than two pregnancies (AOR: 4.39, 95% CI 1.21-15.85). Conclusion: We found a higher proportion of stillbirths than the National report and studies from other countries. Modifiable risk factors contributed to a higher risk of stillbirths in the study setting. Therefore, early identification and management of complications and reducing delays in getting care at each level of health system could avert preventable stillbirths. Key words: stillbirths, pregnancy outcomes, maternal health, Sothern Ethiopia

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