Prevalence and risk factors of preoperative frailty in Chinese elderly inpatients with gastric and colorectal cancer undergoing surgery: a single-center cross-sectional study using the Groningen Frailty Indicator

2021 ◽  
Author(s):  
Qianqian Zhang ◽  
Meng Zhang ◽  
Shaohua Hu ◽  
Lei Meng ◽  
Jing Xi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Single Center ◽  
Cross Sectional ◽  
Chinese Elderly ◽  
Groningen Frailty Indicator ◽  
Elderly Inpatients ◽  
Frailty Indicator

Prevalence and Risk Factors of Preoperative Frailty in Chinese Elderly Inpatients with Gastrointestinal Cancer Undergoing Surgery: A Single-center Cross-sectional Study Using the Groningen Frailty Indicator

2021 ◽  
Author(s):  
Qianqian Zhang ◽  
Meng Zhang ◽  
Shaohua Hu ◽  
Lei Meng ◽  
Jing Xi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Cancer ◽  
Handgrip Strength ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Groningen Frailty Indicator ◽  
Elderly Inpatients ◽  
Frailty Indicator

Abstract BackgroundFrailty is emerging as an important determinant for health. Compared with Western countries, research in the field of frailty started at a later stage in China and mainly focused on older community dwellers. Little is known about frailty in Chinese cancer patients, nor the risk factors of frailty. This study aimed to investigate the prevalence of frailty and its risk factors in elderly inpatients with gastrointestinal cancer. MethodsThis cross-sectional study was performed at a tertiary hospital in China from Mar. 2020 to Nov. 2020. The study enrolled 265 inpatients aged 60 and older with gastrointestinal cancer who underwent surgery. The demographic and clinical characteristics, biochemical laboratory parameters, and anthropometric data were collected from all patients. The Groningen Frailty Indicator was applied to assess the frailty status of patients. Multivariate logistic regression model analysis was carried out to identify risk factors of frailty and estimate their 95% confidence intervals. ResultsThe prevalence of frailty in elderly inpatients with gastrointestinal cancer was 43.8%. A multivariate logistic regression analysis showed that older age (OR=1.065, 95% CI: 1.001-1.132, P=0.045), low handgrip strength (OR=4.346, 95% CI: 1.739-10.863, P=0.002), no regular exercise habit (OR=3.228, 95% CI: 1.230-8.469, P=0.017), and low MNA-SF score (OR=11.090, 95% CI: 5.119-24.024, P<0.001) were risk factors of frailty. ConclusionsThis study suggested that the prevalence of frailty was high among elderly inpatients with gastrointestinal cancer. Older age, low handgrip strength, no regular exercise habit, and low MNA-SF score were identified as risk factors of frailty.

scholarly journals Public Awareness and Barriers to Seeking Medical Advice for Colorectal Cancer in the Gaza Strip: A Cross-Sectional Study

2019 ◽  
pp. JGO.18.00252 ◽  
Author(s):  
Mohamedraed Elshami ◽  
Maha Alfaqawi ◽  
Tamer Abdalghafoor ◽  
Ayoob A. Nemer ◽  
Mohammed Ghuneim ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Public Awareness ◽  
Gaza Strip ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Anorectal Pain ◽  
Standard Deviations ◽  
The Gaza Strip

PURPOSE Raising awareness of colorectal cancer (CRC) symptoms for early recognition, reduction of modifiable risk factors, and removing barriers to seeking medical help could lower its mortality. This study aimed to assess the level of public awareness of CRC in the Gaza Strip. MATERIALS AND METHODS This was a cross-sectional study conducted at three hospitals and 10 high schools between September and October 2017. The Arabic version of the validated Bowel Cancer Awareness Measure (BoCAM) questionnaire was used to evaluate awareness of CRC symptoms and risk factors, and barriers to seeking medical help. Adults (age ≥ 18 years) in three major hospitals and adolescents (ages 15 to 17 years) in 10 schools were recruited for face-to-face interviews to complete the BoCAM. RESULTS Of 3,172 potential participants, 3,080 completed the BoCAM (response rate, 97.1%). Among these, 1,578 (51.2%) were adults and 1,614 (52.4%) were females. Persistent abdominal pain was the most commonly recognized CRC symptom (n = 1,899; 61.7%), whereas anorectal pain was the least common (n = 1,056; 34.3%). In total, 2,177 (70.7%) were not confident in recognizing CRC symptoms or signs. Having a bowel disease was the most frequently recognized CRC risk factor (n = 1,456; 47.3%) and diabetes the least recognized (n = 591; 19.2%). The overall mean scores ± standard deviations for recalling and recognizing CRC symptoms were 1.2 ± 1.3 and 4.3 ± 2.3, respectively (out of 9 points). The overall mean scores ± standard deviations for recalling and recognizing CRC risk factors were 0.7 ± 0.8 and 8.0 ± 3.1, respectively (out of 16 points). Emotional barriers were the most commonly reported barriers to seeking medical help, with feeling worried about what a doctor might find as the most common barrier (n = 1,522; 49.4%). CONCLUSION Public awareness of CRC is suboptimal in Gaza. Improving CRC awareness with educational interventions is needed, including in local schools.

scholarly journals Association of Metabolic Syndrome and Cardiovascular Risk Factors Among Colorectal Cancer Patients Attending in Tikur Anbessa Specialized Hospital Oncology Units: A Comparative Cross-sectional Study June, 2017 Addis Ababa, Ethiopia

2020 ◽  
Author(s):  
Shimelis Adugna Elemo ◽  
Bereket Mihretu Awoke
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cancer Patients ◽  
Addis Ababa ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Colorectal Cancer Patients

Abstract Background: Metabolic syndrome and obesity are risk factors for developing type 2 diabetes mellitus and/or cardiovascular disease, especially stroke. Obesity-associated diseases account for a large portion of public health challenges. Among obesity-related disorders, a direct and independent relationship has been ascertained for colorectal cancer. Objective: The aim of this study was to determine the prevalence of metabolic syndrome and other cardiovascular risk factors, including dyslipidemia, hypertension, dietary and exercise practices, tobacco use and body mass index in individual with colorectal cancer patients attending Tikur Anbessa Hospital Oncology department, Addis Ababa.Methods: A comparative cross-sectional study was conducted from February, 2016 to Jun 2017 on 79 patients attending the Oncology clinic at Tikur Anbessa Hospital. Components of metabolic syndrome, including fasting serum glucose, serum triglyceride, serum high density lipoprotein, blood pressure and waist circumference, was measured in all of the patients. In addition, serum total cholesterol, serum low density lipoprotein was measured with 5010 photometers, and information gathered on smoking and other lifestyle practices, including diet and exercise.Result: Of 79 patients, 23 had metabolic syndrome (MS); 58.2% males; mean-age 48.6 years with range (26 to 78) and 41.8 % Female; mean age 44.6 years with range (20 to 78). Among the MS group, 45.6 % had high blood pressure, 26.6 % had increased waist circumference, 67.1% had serum blood glucose level greater than 100 mg/dL, 68.3 % had low high-density lipoprotein cholesterol level, 57 % had increased triglyceride level, and 3.8 % were obese [body mass index (BMI) >30 kg/m2]. 29 % presented 3 criteria of MS. From total colorectal cancer patients 53.2 % had colon cancer, 46.8 % had rectal cancer and 12.7 % had stage I,40.5 % had stage II (IIa,IIb & IIc), 25.3 % had stage III (a,b,c) and 21.5 % had stage IV disease.CONCLUSION: MS is positively associated with adenomas and colorectal cancer. However, there is not enough information in Ethiopia to justify screening in patients with MS. To our knowledge, no previous study has evaluated this association in Ethiopian patients.

Prevalence and Risk Factors of Frailty in a Community-Dwelling Population: The HELIAD Study

2018 ◽  
Vol 32 (1-2) ◽  
pp. 14-24 ◽  
Author(s):  
E. Ntanasi ◽  
M. Yannakoulia ◽  
N. Mourtzi ◽  
G. S. Vlachos ◽  
M. H. Kosmidis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Population Studies ◽  
Frailty Index ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tilburg Frailty Indicator ◽  
Frailty Indicator

Objective: To estimate the prevalence of frailty using five different instruments in a cohort of older adults and explore the association between frailty and various risk factors. Method: 1,867 participants aged 65 years and above were included in the current retrospective cross-sectional study. Frailty was operationalized according to the Fried definition, the FRAIL Scale, the Frailty Index (FI), the Tilburg Frailty Indicator (TFI), and the Groningen Frailty Index (GFI). We explored the role of various frailty risk factors using logistic regression analyses. Results: The prevalence of frailty varied depending on the definition used (Fried definition = 4.1%, FRAIL Scale = 1.5%, FI = 19.7%, TFI = 24.5%, and GFI = 30.2%). The only risk factors consistently associated with frailty irrespectively of definition were education and age. Conclusion: The frailty prevalence reported in our study is similar or lower to that reported in other population studies. Qualitative differences between frailty definitions were observed.

scholarly journals Identifying frailty: do the Frailty Index and Groningen Frailty Indicator cover different clinical perspectives? a cross-sectional study

2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Irene Drubbel ◽  
Nienke Bleijenberg ◽  
Guido Kranenburg ◽  
René JC Eijkemans ◽  
Marieke J Schuurmans ◽  
...  
Keyword(s):  
Frailty Index ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Groningen Frailty Indicator ◽  
Frailty Indicator

scholarly journals Colorectal cancer risk factors in north-eastern Iran: A retrospective cross-sectional study based on geographical information systems, spatial autocorrelation and regression analysis

2019 ◽  
Vol 14 (2) ◽  
Author(s):  
Ladan Goshayeshi ◽  
Ali Pourahmadi ◽  
Majid Ghayour-Mobarhan ◽  
Soheil Hashtarkhani ◽  
Sajad Karimian ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Cross Sectional Study ◽  
Red Meat ◽  
Geographical Information ◽  
Distribution Data ◽  
Sectional Study ◽  
Cross Sectional ◽  
North East ◽  
Study Results

Colorectal cancer (CRC) is the second most common cancer among females and the third most common malignancy in males in the world. No single risk factor has been identified, but there are many interrelated factors that together cause the disease. This retrospective, cross-sectional study aimed to identify potential spatial factors contributing to its geographical distribution. Data concerning 1,089 individuals with CRC from the Khorasan-Razavi Province in Iran, located in the North-East of the country, were obtained from the national CRC registry. Local Moran’s I statistic was performed to identify clustered areas of CRC occurrence and ordinary least squared regression was calculated to predict frequency of the disease based on a set of variables, such as diet, body mass index (BMI) and the proportion of the population ≥50 years of age. Some dissimilarities related to the geography in the province and also some neighbourhood-related similarities and dissimilarities of CRC occurrence in the city of Mashhad were found. A significant regression equation was found (F (4,137)=38.304, P<.000) with an adjusted R2 of 0.6141. The predicted CRC frequency was -58.3581 with the coefficients for average BMI=+1.594878; fibre intake=-0.610335; consumption of red meat +0.078970; and ≥50-year age group =+0.000744. All associations were statistically significant, except the consumption of red meat one. The study results illuminate the potential underlying risk factors in areas where the CRC risk is comparatively high and how the CRC risk factors may play a role in CRC geographic disparity. Further research is required to explain the patterns observed. We conclude that people should include more fibre in their daily diet and decline their BMI to decrease risk of CRC.

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