scholarly journals Usefulness of Simultaneous Measurement of Brain and Muscle rSO2 (Regional Oxygen Saturation) in Shock Patients: a Report of Three Cases

2021 ◽  
Author(s):  
Arisa Muratsu ◽  
Tomoya Hirose ◽  
Mitsuo Ohnishi ◽  
Jotaro Tachino ◽  
Shunichiro Nakao ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Septic Shock ◽  
Oxygen Saturation ◽  
Muscle Tissue ◽  
Simultaneous Measurement ◽  
Oxygen Supply ◽  
Circulatory Failure ◽  
Shock State ◽  
Regional Oxygen Saturation ◽  
The Brain

Abstract BackgroundIn the field of emergency medical care, we often experience a situation in which we cannot measure pulse oximetric saturation (SpO₂) or blood pressure due to circulatory failure associated with shock. However, as we can measure rSO₂ values of the brain even in patients with shock, we hypothesized that we could evaluate the oxygen supply-demand balance between brain and muscle tissue by simultaneously measuring regional oxygen saturation (rSO₂) values of the brain and muscle tissue of patients with shock.Case presentationWe attached a TOS-OR rSO₂ monitor (TOSTEC CO., Tokyo, Japan) to 10 healthy volunteers and measured the rSO₂ values of their brain and muscle for 3 minutes. The rSO₂ values of their brain cerebral regional oxygen saturation (crSO₂) and muscle regional oxygen saturation (mrSO₂) were 77.6±1.6% and 76.2±1.3% (mean ± SD). There was little difference between crSO₂ and mrSO₂ (cerebro-musculoskeletal difference in regional saturation of oxygen; c-mDrSO₂). However, there were discernible amount of c-mDrSO₂ in three cases with shock, Case 1 showed a prolonged shock state due to septic shock caused by bacterial pneumonia. Her crSO₂ values was always higher than her mrSO₂ value, and there was a c-mDrSO₂. Case 2 showed a decrease in mean arterial pressure (MAP) with the development of septic shock caused by intestinal perforation. His crSO₂ value was higher than that of his mrSO₂, and c-mDrSO₂ increased with the decrease of his MAP. Case 3 had a low MAP due to hemorrhagic shock caused by postpartum hemorrhage. Her crSO₂ value was higher than that of her mrSO₂ and a c-mDrSO₂ was present. After resuscitation, the c-mDrSO₂ decreased with the increase in her blood pressure.ConclusionWe evaluated the usefulness of simultaneous measurement of crSO₂ and mrSO₂ as an objective and non-invasive method in shock management. Even if SpO₂ or blood pressure could not be measured due to circulatory failure associated with shock, it was possible to measure the values of crSO₂ and mrSO₂, which changed in real time with fluctuation of the blood pressure. Unlike previous monitoring devices, the rSO₂ monitor may continuously and clearly reflect the changes in local oxygen supply-demand balance.

Regional Oxygen Saturation of the Brain and Peripheral Tissue during Birth Transition of Term Infants

2010 ◽  
Vol 157 (5) ◽  
pp. 740-744 ◽  
Author(s):  
Berndt Urlesberger ◽  
Karin Grossauer ◽  
Mirjam Pocivalnik ◽  
Alexander Avian ◽  
Wilhelm Müller ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Peripheral Tissue ◽  
Term Infants ◽  
Regional Oxygen Saturation ◽  
The Brain

Regional Oxygen Saturation of the Brain during Birth Transition of Term Infants: Comparison between Elective Cesarean and Vaginal Deliveries

2011 ◽  
Vol 159 (3) ◽  
pp. 404-408 ◽  
Author(s):  
Berndt Urlesberger ◽  
Elisabeth Kratky ◽  
Thomas Rehak ◽  
Mirjam Pocivalnik ◽  
Alexander Avian ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Term Infants ◽  
Regional Oxygen Saturation ◽  
Vaginal Deliveries ◽  
Elective Cesarean ◽  
The Brain

Mortality and Regional Oxygen Saturation Index in Septic Shock Patients: A Pilot Study

2011 ◽  
Vol 70 (5) ◽  
pp. 1145-1152 ◽  
Author(s):  
Alejandro Rodriguez ◽  
Thiago Lisboa ◽  
Ignacio Martín-Loeches ◽  
Emili Díaz ◽  
Sandra Trefler ◽  
...  
Keyword(s):  
Septic Shock ◽  
Pilot Study ◽  
Oxygen Saturation ◽  
Saturation Index ◽  
Regional Oxygen Saturation

scholarly journals Usefulness of simultaneous measurement of brain and muscle regional oxygen saturation in shock patients: A report of three cases

2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Arisa Muratsu ◽  
Tomoya Hirose ◽  
Mitsuo Ohnishi ◽  
Jotaro Tachino ◽  
Shunichiro Nakao ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Simultaneous Measurement ◽  
Regional Oxygen Saturation

scholarly journals Effects of Carotid Compression, as Assessed by near Infrared Spectroscopy, upon Cerebral Blood Volume and Haemoglobin Oxygen Saturation

1987 ◽  
Vol 80 (2) ◽  
pp. 83-87 ◽  
Author(s):  
M Ferrari ◽  
E Zanette ◽  
G Sideri ◽  
I Giannini ◽  
C Fieschi ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Oxygen Saturation ◽  
Carotid Endarterectomy ◽  
Near Infrared Spectroscopy ◽  
Oxygen Supply ◽  
Near Infrared ◽  
Cerebral Blood Volume ◽  
Fisher Exact Test ◽  
Compensatory Mechanisms ◽  
The Brain

Near infrared spectroscopy, a recently developed optoelectronic technique, has been studied as a possible method of monitoring the adequacy of cerebral perfusion in 22 patients who were candidates for carotid endarterectomy. Using this technique, changes in haemoglobin volume, haemoglobin oxygen saturation and redox level of cytochrome-coxidase were recorded from the frontoparietal region during routine carotid compression tests performed under continuous electroencephalographic (EEG) monitoring. A highly significant association was found between EEG slowing, indicating impaired cerebral function, and a fall in haemoglobin volume and oxygen saturation, indicating a reduced blood and oxygen supply to the brain (Fisher exact test, P < 10−5). In a few tests haemoglobin volume and oxygen saturation were reduced without changes in the EEG recording. This study raises new issues concerning the compensatory mechanisms taking place during carotid occlusion and suggests that near infrared spectroscopy might be useful in monitoring the blood and oxygen supply to the brain during carotid endarterectomy.

scholarly journals P1246CEREBRAL TISSUE REGIONAL OXYGEN SATURATION AND BLOOD PRESSURE IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Georgios Spanos ◽  
Styliani Paschou ◽  
Christos Dontsios ◽  
Stylianos Fragkidis ◽  
Christos Bantis ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Oxygen Saturation ◽  
Vascular Disease ◽  
Near Infrared ◽  
Cerebral Tissue ◽  
Cerebral Disease ◽  
Regional Oxygen Saturation ◽  
Dialysis Vintage

Abstract Background and Aims Patients undergoing hemodialysis (HD) often develop cerebral disease complications. Cerebral tissue regional oxygen saturation (rSO2) through near-infrared spectroscopy (NIRS) is a non-invasive method for cerebral tissue oxygenation monitoring. The aim of the study was to investigate the relationship between rSO2 and hemodialysis in stable HD patients. Additionally, we wanted to investigate how blood pressure during HD is associated with rSO2. Method This is a single centre cross-sectional study in clinically stable HD patients. Cerebral rSO2 was monitored at the forehead 10min before, during and 10min after HD, using an INVOS 5100C device (Medtronic, United Kingdom). Results Thirty-nine stable HD patients (23 men and 16 women; mean age, 62.4 ± 14.6 years were recruited. Dialysis vintage was 65.7 ± 72.1 months, 9 patients had diabetes mellitus, 12 had vascular disease while 14 were smokers. The baseline rSO2 levels (49.6±9.1 %) were significantly lower in HD patients compared with historic results on healthy subjects. We found no difference in rSO2 results in patients with diabetes mellitus, vascular disease or smoking. Although we found a decrease (figure) in rSO2 when patients start dialysis (10min before vs 10min after starting dialysis 49.6±9.1 vs 48.1±9.9 %, p=0.021) rSO2 value returned to baseline after dialysis (10min before vs 10min after dialysis 49.6±9.1 vs 49.9±5.9 %, p=ns. Systolic blood pressure scientifically dropped during the first hour of dialysis (146.7 ± 21.1 vs 137.3 ± 24.6, p=0.03) and systolic blood pressure drop correlated with rSO2. Three patients developed hypotensive episodes requiring iv fluids but these hypotensive episodes had no correlation with rSO2 variations. Conclusion Cerebral rSO2 decreases while patients are on dialysis but return to baseline after dialysis. Blood pressure variations correlate with rSO2 levels but rSO2 do not forecast hypotensive episodes on dialysis.

Effect of fluid bolus triggers and their combination on fluid responsiveness in optimization phase of severe sepsis and septic shock resuscitation

MedPharmRes ◽  
2018 ◽  
Vol 2 (3) ◽  
pp. 27-32
Author(s):  
Bien Le ◽  
Dai Huynh ◽  
Mai Tuan ◽  
Minh Phan ◽  
Thao Pham ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Septic Shock ◽  
Severe Sepsis ◽  
Fluid Responsiveness ◽  
Statistical Significance ◽  
Venous Pressure ◽  
Fluid Bolus ◽  
Low Blood Pressure ◽  
Low Central Venous Pressure ◽  
Sepsis And Septic Shock

Objectives: to evaluate the fluid responsiveness according to fluid bolus triggers and their combination in severe sepsis and septic shock. Design: observational study. Patients and Methods: patients with severe sepsis and septic shock who already received fluid after rescue phase of resuscitation. Fluid bolus (FB) was prescribed upon perceived hypovolemic manifestations: low central venous pressure (CVP), low blood pressure, tachycardia, low urine output (UOP), hyperlactatemia. FB was performed by Ringer lactate 500 ml/30 min and responsiveness was defined by increasing in stroke volume (SV) ≥15%. Results: 84 patients were enrolled, among them 30 responded to FB (35.7%). Demographic and hemodynamic profile before fluid bolus were similar between responders and non-responders, except CVP was lower in responders (7.3 ± 3.4 mmHg vs 9.2 ± 3.6 mmHg) (p 0.018). Fluid response in low CVP, low blood pressure, tachycardia, low UOP, hyperlactatemia were 48.6%, 47.4%, 38.5%, 37.0%, 36.8% making the odd ratio (OR) of these triggers were 2.81 (1.09-7.27), 1.60 (0.54-4.78), 1.89 (0.58-6.18), 1.15 (0.41-3.27) and 1.27 (0.46-3.53) respectively. Although CVP < 8 mmHg had a higher response rate, the association was not consistent at lower cut-offs. The combination of these triggers appeared to raise fluid response but did not reach statistical significance: 26.7% (1 trigger), 31.0% (2 triggers), 35.7% (3 triggers), 55.6% (4 triggers), 100% (5 triggers). Conclusions: fluid responsiveness was low in optimization phase of resuscitation. No fluid bolus trigger was superior to the others in term of providing a higher responsiveness, their combination did not improve fluid responsiveness as well.

The Effects of Passive and Active Smoking on Brachial and radial Blood Pressure and Some Other Physical Factors in Healthy Young Adults

2017 ◽  
Vol 5 (3) ◽  
pp. 259
Author(s):  
Shireen H. Ramadhan ◽  
Shamil K. Talal ◽  
Wasfiya A. Moner
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Oxygen Saturation ◽  
Oxygen Concentration ◽  
Tobacco Smoke ◽  
Blood Pressure Measurement ◽  
Reference Level ◽  
Physical Factors ◽  
New Device ◽  
Active Smoker

Tobacco smoke is enormously harmful to human health, there’s no safe way to smoke. The primary objective of this study is to analyze the role of tobacco smoke compounds and their ability to damage the cardiovascular system and, in particular, to interfere with blood pressure (Brachial and radial pressure), heart rate and partly on the percentage blood Oxygen saturation. A new device has been manufactured which is unique for measuring the level of smoke, to obtained privies readings, the device had fixed to the first reference level آ and starting up from it. The effect of smoking has been studied on (26) male passive (26) active smoker volunteer, (14) female passive and (14) female active smoker participants. The results has been showed that the blood pressure and heart rate has been increased with increasing the number of cigarettes in both genders for passive and active smokers. However, this effect for male was more pronounced comparing with females for passive and active smokers. In the case of oxygen saturation concentration percentage, for males the change of oxygen concentration percentage was not stable. In other words, it was fluctuated with the number of cigarettes. But for females the oxygen concentration was decreased but not too much. This means that this effect was not pronounced. this study found آ that the most pronounced effect has been shown by male’s comparison to females for both passive and active smokers. As well as in nonsmoker’s males, the relation between heart rate and smoke level is inversely proportional. While in male and female smokers and female nonsmokers the relation is proportional. In all cases the relation between the smoke level and time of smoking is inversely proportional. Finally males& females are affected differently by tobacco use; the sensitivities to smoke for males are higher than in females for passive and active smokers in both brachial and radial blood pressure measurement.

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