scholarly journals P1246CEREBRAL TISSUE REGIONAL OXYGEN SATURATION AND BLOOD PRESSURE IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Georgios Spanos ◽  
Styliani Paschou ◽  
Christos Dontsios ◽  
Stylianos Fragkidis ◽  
Christos Bantis ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Oxygen Saturation ◽  
Vascular Disease ◽  
Near Infrared ◽  
Cerebral Tissue ◽  
Cerebral Disease ◽  
Regional Oxygen Saturation ◽  
Dialysis Vintage

Abstract Background and Aims Patients undergoing hemodialysis (HD) often develop cerebral disease complications. Cerebral tissue regional oxygen saturation (rSO2) through near-infrared spectroscopy (NIRS) is a non-invasive method for cerebral tissue oxygenation monitoring. The aim of the study was to investigate the relationship between rSO2 and hemodialysis in stable HD patients. Additionally, we wanted to investigate how blood pressure during HD is associated with rSO2. Method This is a single centre cross-sectional study in clinically stable HD patients. Cerebral rSO2 was monitored at the forehead 10min before, during and 10min after HD, using an INVOS 5100C device (Medtronic, United Kingdom). Results Thirty-nine stable HD patients (23 men and 16 women; mean age, 62.4 ± 14.6 years were recruited. Dialysis vintage was 65.7 ± 72.1 months, 9 patients had diabetes mellitus, 12 had vascular disease while 14 were smokers. The baseline rSO2 levels (49.6±9.1 %) were significantly lower in HD patients compared with historic results on healthy subjects. We found no difference in rSO2 results in patients with diabetes mellitus, vascular disease or smoking. Although we found a decrease (figure) in rSO2 when patients start dialysis (10min before vs 10min after starting dialysis 49.6±9.1 vs 48.1±9.9 %, p=0.021) rSO2 value returned to baseline after dialysis (10min before vs 10min after dialysis 49.6±9.1 vs 49.9±5.9 %, p=ns. Systolic blood pressure scientifically dropped during the first hour of dialysis (146.7 ± 21.1 vs 137.3 ± 24.6, p=0.03) and systolic blood pressure drop correlated with rSO2. Three patients developed hypotensive episodes requiring iv fluids but these hypotensive episodes had no correlation with rSO2 variations. Conclusion Cerebral rSO2 decreases while patients are on dialysis but return to baseline after dialysis. Blood pressure variations correlate with rSO2 levels but rSO2 do not forecast hypotensive episodes on dialysis.

scholarly journals Cerebral Tissue Regional Oxygen Saturation as a Valuable Monitoring Parameter in Pediatric Patients Undergoing Extracorporeal Membrane Oxygenation

2021 ◽  
Vol 9 ◽  
Author(s):  
Song Chen ◽  
Fang Fang ◽  
Wenjun Liu ◽  
Chengjun Liu ◽  
Feng Xu
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Oxygen Saturation ◽  
Near Infrared ◽  
Pediatric Patients ◽  
Trial Registry ◽  
Cerebral Tissue ◽  
Clinical Trial Registry ◽  
Variation Trend ◽  
Regional Oxygen Saturation ◽  
Membrane Oxygenation

Objective: Brain function monitoring technology for extracorporeal membrane oxygenation (ECMO) support has been developing quite slowly. Our objective was to explore the data distribution, variation trend, and variability of cerebral tissue regional oxygen saturation (CrSO2) in pediatric patients undergoing ECMO.Methods: Eight patients who received venoarterial ECMO (V-A ECMO) were included in our study. All of them accepted continuous CrSO2 monitoring by near-infrared spectroscopy (NIRS) within 12 h of ECMO initiation until ECMO wean. Differences in the CrSO2 distribution characteristic, the variation trend of daily CrSO2, and the variability of CrSO2 for the first 5 days following ECMO initiation were compared between survivors and non-survivors according to pediatric intensive care unit (PICU) mortality.Results: The percentage of time of CrSO2 <60% against the whole monitoring time was significantly lower in survivors in both hemispheres {right: 4.34% [interquartile range (IQR) = 0.39–8.55%] vs. 47.45% [IQR = 36.03–64.52%], p = 0.036; left: 0.40% [IQR = 0.01–1.15%] vs. 30.9% [IQR = 26.92–49.62%], p = 0.036}. Survivors had significantly higher CrSO2 on the first 4 days. Root mean of successive squared differences (RMSSD), the variability variable of CrSO2, was significantly lower in survivors (right: 3.29 ± 0.79 vs. 6.16 ± 0.67, p = 0.002; left: 3.56 ± 1.20 vs. 6.04 ± 1.44, p = 0.039).Conclusion: Lower CrSO2, CrSO2 <60% over a longer period of time, and higher fluctuation of CrSO2 are likely associated with PICU mortality in pediatric patients undergoing V-A ECMO.Clinical Trial Registry: URL: http://www.chictr.org.cn/showproj.aspx?proj=46639, trial registry number: ChiCTR1900028021.

scholarly journals The effects of ultrasound and shockwave treatment on muscle regional oxygen saturation using near-infrared spectroscopy

2018 ◽  
Vol 64 (3) ◽  
Author(s):  
Anna Lubkowska ◽  
Aleksandra Radecka ◽  
Miłosz Parchimowicz ◽  
Iwona Bryczkowska ◽  
Monika Chudecka
Keyword(s):  
Infrared Spectroscopy ◽  
Oxygen Saturation ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Ultrasound Therapy ◽  
Extracorporeal Shockwave Therapy ◽  
Extracorporeal Shockwave ◽  
Regional Oxygen Saturation ◽  
Shockwave Therapy

ABSTRAKTWstęp: Terapeutyczne fale ciśnieniowe są często stosowane w leczeniu różnych schorzeń układu mięśniowo-szkieletowego, niemniej jednak efekt biologiczny ich odziaływania wciąż nie został w pełni poznany. W przedstawionych badaniach oceniono wpływ fal dźwiękowych o różnej sile bodźca stosowanych w terapii falą ultradźwiękową (ultrasound therapy – UST) i pozaustrojową radialną falą uderzeniową (radial extracorporeal shockwave therapy – rESWT) na wysycenie tlenem tkanki mięśniowej i temperaturę powierzchniową w kontekście potencjalnego efektu troficznego przy użyciu spektroskopii bliskiej podczerwieni (near-infrared spectroscopy).Materiały i metody: Badaniem objęto 41 zdrowych ochotników, w tym 27 poddanych UST i 14 rESWT, w wieku 22–48 lat. Pomiar saturacji tkankowej i temperatury powierzchni obszaru mięśnia podgrzebieniowego wykonano 4-krotnie: bezpośrednio przed (T0) i po (T1) oraz 15 (T2) i 30 min po aplikacji bodźca (T3). Saturacje mięśni zmierzono na 2 głębokościach: 20 mm (czujnik 1 – S1) i 12,5 mm (czujnik 2 – S2).Wyniki: Wartość regionalnej perfuzji tkankowej (rSO2 [%]) istotnie zmniejszyła się natychmiast oraz po 15 i 30 min od UST. Wartości początkowe, wynoszące 71,26 ±5,47% (S1) i 88,26 ±2,89% (S2) dla odpowiednich głębokości, znacząco spadły po bodźcowaniu odpowiednio do 68,89 ±5,26% (T2) i 68,93 ±5,12% (T3) na głębokości 20 mm i 86,63 ±5,37% (T1) i 86,52 ±3,38% (T2) na głębokości 12,5 mm.Wnioski: Uzyskane wyniki wskazują, że tylko leczenie za pomocą UST ma znaczący wpływ na zmiany oksymetrii regionalnej, co tłumaczy się ich działaniem przekrwiennym i termicznym w tkankach głębokich, które z kolei indukują dysocjacje tlenu z hemoglobiny do tkanek i efekt troficzny.

scholarly journals Systolic Blood Pressure and Vascular Disease in Men Aged 65 Years and Over

Hypertension ◽  
2017 ◽  
Vol 69 (6) ◽  
pp. 1053-1059 ◽  
Author(s):  
Ben Lacey ◽  
Jonathan Golledge ◽  
Bu B. Yeap ◽  
Sarah Lewington ◽  
Kieran A. McCaul ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Vascular Disease
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