scholarly journals Single-Dose Intraoperative Steroid Administration Does Not Impact Early Atrial Fibrillation Recurrence

2021 ◽  
Author(s):  
Kolade M. Agboola ◽  
Michael Dietrich ◽  
Roshan Karki ◽  
Fahad Lodhi ◽  
Trevon McGill ◽  
...  
Keyword(s):  
Single Dose ◽  
Catheter Ablation ◽  
Postoperative Nausea ◽  
Group Versus ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Cardiac Monitoring ◽  
P Value ◽  
Dexamethasone Group ◽  
Af Recurrence

Abstract Purpose: To evaluate the effect of single-dose intravenous dexamethasone on AF recurrence following radiofrequency catheter ablation. Methods: A cohort of 94 adult patients (>18 years) underwent catheter ablation at Mayo Clinic Rochester from January to March 2019. Only first-time ablation patients were included, with all re-do ablations excluded to minimize heterogeneity. Administration of intraoperative dexamethasone 4 mg or 8 mg was determined by chart review from the procedure. At our institution, intraoperative intravenous steroids are administered for postoperative nausea and vomiting (PONV) prophylaxis at the discretion of the anesthesiologist. AF recurrence was determined by ECG or cardiac monitoring at less than 3 months or between 3 months and 1 year with an in-person follow-up visit. Results: A total of 36.2% of patients received intravenous dexamethasone compared to 63.8% who did not (providing a 2:1 comparison group). The incidence of documented AF or flutter lasting greater than 30 seconds was 20.6% in the dexamethasone group versus 21.7% in the non-dexamethasone group, p value 1.00. AF or atrial flutter recurrence from 3 months to 1 year was 20.6% in the dexamethasone group compared to 21.7% in the non-dexamethasone group, p value 1.00. Conclusion: These data suggest that intraoperative intravenous dexamethasone administered during AF ablation for postoperative nausea and vomiting prophylaxis does not have a significant effect on AF recurrence rates.

scholarly journals Single-dose i.v. granisetron in the prevention of postoperative nausea and vomiting

1996 ◽  
Vol 76 (4) ◽  
pp. 515-518 ◽  
Author(s):  
A J Wilson ◽  
P Diemunsch ◽  
B G Lindeque ◽  
H Scheinin ◽  
H S Helbo-Hansen ◽  
...  
Keyword(s):  
Single Dose ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting

Single-Dose Tropisetron for Preventing Postoperative Nausea and Vomiting After Breast Surgery

1998 ◽  
Vol 87 (4) ◽  
pp. 931-935 ◽  
Author(s):  
Matthew T. V. Chan ◽  
Po Tong Chui ◽  
Wai Sun Ho ◽  
Walter W. K. King
Keyword(s):  
Single Dose ◽  
Postoperative Nausea ◽  
Breast Surgery ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting

scholarly journals Effectiveness of Propofol versus Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Ear, Nose, and Throat Surgery in Tikur Anbessa Specialized Hospital and Yekatit 12th Hospital, Addis Ababa, Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Abere Tilahun Bantie ◽  
Wosenyeleh Admasu ◽  
Sintayehu Mulugeta ◽  
Abera Regassa Bacha ◽  
Desalegn Getnet Demsie
Keyword(s):  
Postoperative Nausea ◽  
Addis Ababa ◽  
Statistical Significance ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Dexamethasone Group ◽  
Ent Surgery ◽  
Group A ◽  
Group B ◽  
Nose And Throat

Background. Postoperative nausea and vomiting (PONV) remain as common and unpleasant and highly distressful experience following ear, nose, and throat surgery. During ENT surgery, the incidence of PONV could be significantly reduced in patients who receive dexamethasone and propofol as prophylaxis. However, the comparative effectiveness of the two drugs has not been assessed. The aim of this study was to compare the effectiveness of propofol and dexamethasone for prevention of PONV in ear, nose, and throat surgery. Methods. This study was conducted in 80 patients, with ASA I and II, aged 18–65 years, and scheduled for ENT surgery between December 20, 2017, and March 20, 2018. Patients were randomly assigned to Group A and Group B. Immediately after the procedure, Group A patients received single dose of intravenous (IV) dexamethasone (10 mg/kg) and Group B patients were given propofol (0.5 mg/kg, IV), and equal follow-up was employed. The incidence of PONV was noted at 6th, 12th, and 24th hour of drug administration. Independent t-test and Mann–Whitney test were used for comparison of symmetric numerical and asymmetric data between groups, respectively. Categorical data were analyzed with the chi-square test, and p value of < 0.05 was considered as level of significance. Results. The incidences of PONV throughout the 24-hour postoperative period were 35% in the propofol group and 25% in the dexamethasone group. Statistical significance was found in incidence of PONV (0% versus 22.5%) and use of antiemetic (0% versus 5%) between dexamethasone and propofol groups, respectively, at 12–24 hours. Over 24 hours, 5% in dexamethasone group and 12.5% in propofol group developed moderate PONV, while none of the participants felt severe PONV. Conclusions. Dexamethasone was more effective than propofol to prevent PONV with lower requirements of rescue antiemetics.

Single Dose Ondansetron for Prevention of Postoperative Nausea and Vomiting

1995 ◽  
Vol 39 (3) ◽  
pp. 194
Author(s):  
N. VOLPE ◽  
A. GESINI ◽  
S. COLLINI ◽  
L. SARLI ◽  
M. T. GRASSANO ◽  
...  
Keyword(s):  
Single Dose ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting

scholarly journals Pengaruh Terapi Komplementer Akupresur terhadap Mual Muntah Pasca Operasi di RSUD Dr. H. Abdul Moeloek Provinsi Lampung

2017 ◽  
Vol 8 (3) ◽  
pp. 382
Author(s):  
El Rahmayati ◽  
Anggi Irawan ◽  
Tumiur Sormin
Keyword(s):  
Postoperative Nausea ◽  
Complementary Therapies ◽  
Postoperative Nausea And Vomiting ◽  
Sampling Technique ◽  
Nausea And Vomiting ◽  
Bivariate Analysis ◽  
Control Group ◽  
P Value ◽  
The Difference ◽  
Post Operative Nausea

<p class="Normal1">Postoperative Nausea and vomiting (PONV) is a common complication after surgery.The incidence of postoperative nausea vomiting is approximately 30% of all patients undergoing inpatient surgery and 70% of cases occur within the first 24 hours. One of nausea and vomiting treatment is non-pharmacological therapies with complementary acupressure therapy. Furthermore, the research was conducted to determine the effect of acupressure complementary therapies against postoperative nausea and vomiting.The research was Quasi-Experimental research design Non-equivalent Control Group, the sampling technique used purposive sampling technique. Based on results of sample calculation used amounted to 22 respondents, consisting of 11 experimental groups and 11 control groups. Collecting data was used questionnaire and analyzed using univariate and bivariate analysis by Wilcoxon and Mann-Whitney with α values (&lt;0.05).The results showed the difference in score of nausea and vomiting the first and second measurements in the control group given a placebo action is 0.91 with a p-value (0.26). Nausea and vomiting difference in scores obtained before and after acupressure complementary therapies in the experimental group was 2:18 with a p-value (0.004). As well as the difference in scores obtained post-operative nausea and vomiting in the control group and the experiment is 1:27 with the p-value (0.009). The above statistical test results can be concluded that there was the effect of complementary acupressure therapy on postoperative nausea vomiting. Based on the conclusion of the research, the authors suggest that complementary acupressure therapy can be applied as a companion therapy and it is expected that nursing staff can learn complementary acupressure therapy.</p>

scholarly journals Incidence of post-operative nausea and vomiting and it’s predictors among adult elective surgical patients at Jimma Medical Center, South West Ethiopia

2020 ◽  
Author(s):  
Mohammed Suleiman Obsa ◽  
Dinkisisa Chemeda Edosa ◽  
Zemenu Muluken Desalegn ◽  
Nega Desalegn Fanta ◽  
Sintayehu Mulugeta Tamiru ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Postoperative Nausea ◽  
Medical Center ◽  
Multiple Logistic Regression Analysis ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
P Value ◽  
Multiple Logistic Regression ◽  
Cross Sectional ◽  
Post Operative Nausea

Abstract Background Post-operative nausea and vomiting is the most frequent side effect of anesthesia. It affects 20 - 30% of all post-operative and 70%-80% high risk patients. Consequently, it is one of the most frequently observed adverse events associated with the provision of anesthesia. Thus this study is aimed to assess the incidence and associated factors of post-operative nausea and vomiting. Methods This cross-sectional study was conducted using a consecutive sampling method. Regular supervision and follow up were made. Data was entered in to Epi info version 7 software and transported to SPSS version 20 for analysis. Odd ratio and 95% confidence interval was computed. The findings of the study were reported using tables, figures and narration. Variables that were found to be candidate (p value < 0.25) on binary logistic regression entered into a multiple logistic regression analysis to identify independent predictors of post-operative nausea and vomiting. Results The results of this study indicated that the incidence of postoperative nausea and vomiting was 27.4% . Output of multiple logistic regression revealed that female sex (AOR = 4.065 (2.090 - 7.906), history of motion sickness (AOR = 2.836 (1.582 - 5.083), Gynecologic type of surgery (AOR = 3.782 (1.156 - 12.373), long duration of anaesthesia (> 60 min) (AOR = 2.974 (1.491 - 5.933) and administration of post-operative opioids (AOR = 2.333 (1.221 - 4.457) were considered as independent predictors of postoperative nausea and vomiting at P value < 0.05. Conclusion The present finding has shown that the overall incidence of postoperative nausea and vomiting is high 27.4% therefore provision of anti-emetic prophylaxis is reccomended.

scholarly journals COMPARATIVE EVALUATION OF SINGLE DOSE PALONOSETRON AND GRANISETRON IN MIDDLE EAR SURGERIES FOR PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING.

2020 ◽  
pp. 39-42
Author(s):  
Anjali P. Savargaonkar ◽  
Dipakkumar H. Ruparel ◽  
Uttam Patil
Keyword(s):  
Single Dose ◽  
Middle Ear ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Middle Ear Surgery ◽  
Ear Surgery ◽  
Post Operative Nausea ◽  
Rescue Antiemetic

Background and aims: Palonosetron 5HT 3 antagonist have been evaluated in delayed chemotherapy induced nausea and vomiting but its antiemetic efficacy after middle ear surgery is less clear which is high risk for post operative nausea and vomiting.( PONV). This study aimed to evaluate whether Palonosetron conferred any advantage over Granisetron in terms of duration of prophylaxis and its effect on the incidence and severity of PONV in patients undergoing middle ear surgeries (MES) when used as single dose prophylactic antiemetic. Methods: One hundred ASA I and II patients of either gender aged 18 to 60 were randomly assigned into group P (Palonosetron n=50) or group G( Granisetron n=50), by computerised randomisation. Analysis was done in terms of incidence and severity of nausea, vomiting and rescue antiemetic usage till 72 hours of surgery. Results: During 72 hours, group P had more number of complete responders than in group G (56% vs. 34%). This difference was more significant after 24hours. 50% of patients in group G as against 28% in group required rescue antiemetic. Conclusion: Single dose prophylactic Palonosetron 0.075 mg and 2.5 mg Granisetron conferred similar protection against postoperative nausea and vomiting for initial six hours postoperatively but Palonosetron was more effective than Granisetron for long term prophylaxis over 72 hours against PONV after MES without significant adverse effects.

Dexamethasone Versus Ondansetron in Preventing Postoperative Nausea and Vomiting In Laparoscopic Surgery

2021 ◽  
Vol 17 (3) ◽  
pp. 222-226
Author(s):  
Anum Malik ◽  
Arshad Shahani ◽  
Jawad Zahir ◽  
Hassam Zulfiqar ◽  
Tabassum Aziz
Keyword(s):  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
P Value ◽  
Inclusion Criteria ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Group A ◽  
The Mean ◽  
Group B

Objective: To compare the efficacy of dexamethasone 8mg versus ondansetron 4mg in preventing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy Methodology: This quasi-experimental study was conducted at the Department of Anaesthesia and Intensive Care, Holy Family Hospital from 29th July 2018 to 28th January 2019.  Anesthesia was induced with propofol (2mg/kg IV) and Atracurium (0.5 mg/kg IV) was given to facilitate tracheal intubation. Nalbuphine (0.2mg/kg) was used as analgesic.Patients were randomly divided into two groups. Patients in Group A received 4mg ondansetron at end of surgery and Group B received 8mg dexamethasone at induction. Results: A total of 90 patients were included according to the inclusion criteria of the study. The mean age (years) in the study was 37.11+10.60 years. Frequency and percentage of nausea (up to 24 hours) among both the groups was 28 (62.2) and 28 (62.2) respectively (p-value = 1.0) while the frequency and percentage of vomiting (within 24 hours after extubation) was 28 (62.2) and 27 (60.0) respectively (p-value = 0.829) Conclusion: The study concluded that there was no significant difference dexamethasone and ondansetron in preventing postoperative nausea and vomiting.

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