scholarly journals Deep Meta Tool: GUI tool to obtain Mean and Standard Deviation (SD) from Median and Interquartile range (IQR)

2021 ◽  
Author(s):  
Deepanshu Sharma ◽  
Surya Priya Ulaganathan ◽  
Vinay Sharma ◽  
Sakshi Piplani ◽  
Ravi Ranjan Kumar Niraj
Keyword(s):  
Standard Deviation ◽  
Input Data ◽  
Meta Analysis ◽  
Statistical Procedure ◽  
Interquartile Range ◽  
Raw Data ◽  
Sample Data

Abstract Background and objectivesMeta-analysis is a statistical procedure which enables the researcher to integrate the results of various studies that were conducted for the same purpose. However, more often than not, researchers find themselves in a position unable to proceed further due to the complexity of the mathematics involved and unavailability of raw data. To alleviate the said difficulty, we are presenting a tool that will enable researchers to process raw data.MethodsThe GUI tool is written in python. The tool offers an automated conversion and obtainment of mean and standard deviation (SD) from median and interquartile range, utilizing the methods offered by Hozo et al. 2005 and Bland 2015.ResultsThe tool is tested on some sample data and validation is performed for Bland method on the data provided in the Bland method publication (14).ConclusionsThe provided tool is an easy alternative for the preparation of input data required for clinical meta-analysis in the required format.

A New Method of Rolling Prediction for Gas Emission Based on Wavelet Neural Network

2011 ◽  
Vol 383-390 ◽  
pp. 1500-1506
Author(s):  
Yu Min Pan ◽  
Xiao Yu Zhang ◽  
Peng Qian Xue
Keyword(s):  
Neural Network ◽  
Input Data ◽  
Wavelet Neural Network ◽  
New Method ◽  
Neutral Network ◽  
Gas Emission ◽  
Sample Data ◽  
Simulation Results

A new method of rolling prediction for gas emission based on wavelet neural network is proposed in this paper. In the method, part of the sample data is selected, which length is constant, and the data is reselected as the next prediction step. Then a wavelet neutral network is adopted to prediction which input data is rolling, the sequence model of rolling prediction is thus constructed. Simulation results have proved that the method is valid and feasible.

scholarly journals Serum Concentration of Antibodies to Mumps, but Not Measles, Rubella, or Varicella, Is Associated with Intake of Dietary Fiber in the NHANES, 1999–2004

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 813
Author(s):  
Cynthia B. Van Van Landingham ◽  
Debra R. Keast ◽  
Matthew P. Longnecker
Keyword(s):  
Measurement Error ◽  
Dietary Fiber ◽  
Meta Analysis ◽  
Serum Antibody ◽  
Potential Effect ◽  
Interquartile Range ◽  
Antibody Concentration ◽  
Fiber Intake ◽  
Food Groups ◽  
Percentage Difference

Treatment with prebiotics, a type of dietary fiber, was recently shown to increase antibody concentrations following influenza vaccination in a meta-analysis of clinical trials. In observational epidemiologic studies it is not possible to estimate intake of prebiotics, but quantifying intake of dietary fiber is routine. Our objective was to investigate the potential effect of dietary fiber on immunogenicity. We examined serum antibody concentrations (Measles, Mumps, Rubella, and Varicella) in relation to dietary fiber in more than 12,000 subjects in the U.S. National Health and Nutrition Examination Survey (NHANES) for the period 1999–2004. Data from one (1999–2002) or two (2003–2004) dietary recalls were used to calculate fiber intake. For Mumps the adjusted percentage difference in antibody concentration per interquartile range intake in energy-adjusted dietary fiber was 6.34% (95% confidence interval, 3.10, 9.68). Fiber from grain-based foods was more positively associated than fiber from other fiber-containing food groups. The association was slightly larger among subgroups with higher fiber intake, greater interquartile range in fiber intake, and less measurement error. Furthermore, based on the reliability of the diet recalls in 2003–2004, we calculated that the percentage difference per interquartile increment was substantially attenuated by measurement error. Dietary fiber may have a favorable influence on the immunogenicity of some vaccines or natural infections.

scholarly journals Reproducible and Transparent Research Practices in Published Neurology Research

2019 ◽  
Author(s):  
Shelby Rauh ◽  
Trevor Torgerson ◽  
Austin L. Johnson ◽  
Jonathan Pollard ◽  
Daniel Tritz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Conflict Of Interest ◽  
Data Extraction ◽  
Meta Analysis ◽  
Research Practices ◽  
Raw Data ◽  
Replication Studies ◽  
Study Materials ◽  
Funding Sources ◽  
Pubmed Search

AbstractBackgroundThe objective of this study was to evaluate the nature and extent of reproducible and transparent research practices in neurology research.MethodsThe NLM catalog was used to identify MEDLINE-indexed neurology journals. A PubMed search of these journals was conducted to retrieve publications over a 5-year period from 2014 to 2018. A random sample of publications was extracted. Two authors conducted data extraction in a blinded, duplicate fashion using a pilot-tested Google form. This form prompted data extractors to determine whether publications provided access to items such as study materials, raw data, analysis scripts, and protocols. In addition, we determined if the publication was included in a replication study or systematic review, was preregistered, had a conflict of interest declaration, specified funding sources, and was open access.ResultsOur search identified 223,932 publications meeting the inclusion criteria, from which 300 were randomly sampled. Only 290 articles were accessible, yielding 202 publications with empirical data for analysis. Our results indicate that 8.99% provided access to materials, 9.41% provided access to raw data, 0.50% provided access to the analysis scripts, 0.99% linked the protocol, and 3.47% were preregistered. A third of sampled publications lacked funding or conflict of interest statements. No publications from our sample were included in replication studies, but a fifth were cited in a systematic review or meta-analysis.ConclusionsCurrent research in the field of neurology does not consistently provide information needed for reproducibility. The implications of poor research reporting can both affect patient care and increase research waste. Collaborative intervention by authors, peer reviewers, journals, and funding sources is needed to mitigate this problem.

Accessing Remote Locations

2011 ◽  
pp. 173-185
Author(s):  
Jana Polgar ◽  
Robert Mark Braum ◽  
Tony Polgar
Keyword(s):  
Web Services ◽  
Web Service ◽  
Data Stream ◽  
Input Data ◽  
Response Times ◽  
Alternative Solution ◽  
Raw Data ◽  
Remote Locations ◽  
The Web ◽  
Server Process

Most of today’s portal implementations provide a model that facilitates plugging various components (portlets) into the portal infrastructure. Portlets run locally on the portal server, process input data, and render output. A local portlet and a good caching strategy for the content improves the response times, performance, and scalability of portal systems. However, very often we need to access remote Web services. One solution is to use a local portlet to access a remote Web service via its interface, obtain the required results as a raw data stream, and locally render the results in a fragment. This approach is relevant for data-oriented Web services. An alternative solution is to equip the Web service with an additional interface in the form of a portlet. When the Web service is called, it returns the entire portlet instead of raw data. This approach is suitable for presentation-oriented Web services.

scholarly journals Blunt and Penetrating Liver Trauma have Similar Outcomes in the Modern Era

2020 ◽  
pp. 145749692092164
Author(s):  
A. A. Keizer ◽  
J. H. C. Arkenbosch ◽  
V. Y. Kong ◽  
R. Hoencamp ◽  
J. L. Bruce ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Injury Severity ◽  
Mortality Rates ◽  
Liver Trauma ◽  
Interquartile Range ◽  
Shock Index ◽  
Hepatic Trauma ◽  
Revised Trauma Score ◽  
The Mean ◽  
Trauma Score

Background: The trend in liver trauma management has progressively become increasingly conservative. However, a vast majority of literature focuses heavily on the management of blunt trauma. This study reviews the management of hepatic trauma at a major trauma center in a developing world setting, in order to compare blunt and penetrating liver trauma and to define current management algorithms and protocols. Methods: All patients who sustained liver trauma between 2012 to 2018 were identified in the Hybrid Electronic Medical Registry and extracted for further analysis. Results: A total of 808 patients with hepatic trauma were managed by our trauma center. There were 658 males and 150 females. The mean age was 30 years (standard deviation 13.3). A total of 68 patients died (8.2%) and a total of 290 (35%) patients required intensive care unit admission. The mean presenting shock index was 0.806 (standard deviation 0.67–1.0), the median Injury Severity Score was 18 (interquartile range 10–25) and the mean Revised Trauma Score was 12 (standard deviation 11–12). There were 367 penetrating and 441 blunt liver injuries. The age distribution was similar in both groups. There were significantly less females in the penetrating group. The shock index and the Injury Severity Score on presentation were significantly worse in the blunt group, respectively: 0.891 (standard deviation 0.31) versus 0.845 (standard deviation 0.69) (p < 0.001) and score 21 (interquartile range 13–27) versus 16 (interquartile range 9–20) (p < 0.01). The opposite applied to the Revised Trauma Score of 11.75 (standard deviation 0.74) versus 11.19 (standard deviation 1.3) (p < 0.001). There were significantly more associated intra-abdominal injuries in the penetrating group than the blunt group, in particular that of hollow organs, and 84% of patients with a penetrating injury underwent a laparotomy while only 33% of the blunt injuries underwent a laparotomy. The mortality rate was comparable between both groups. Conclusion: Hepatic trauma is still associated with a high morbidity rate, although there have been dramatic improvements in mortality rates over the last three decades. The mortality rates for blunt and penetrating liver trauma are now similar. Non-operative management is feasible for over two-thirds of blunt injuries and for just under 20% of penetrating injuries.

scholarly journals Effect sizes and meta-analysis indicate no sex dimorphism in the human or rodent corpus callosum

1998 ◽  
Vol 21 (3) ◽  
pp. 338-339
Author(s):  
Douglas Wahlsten ◽  
Katherine M. Bishop
Keyword(s):  
Standard Deviation ◽  
Corpus Callosum ◽  
Brain Size ◽  
Meta Analysis ◽  
Effect Sizes ◽  
Sex Dimorphism ◽  
Standard Deviations ◽  
Average Size

Sex dimorphism occurs when group means differ by four or more standard deviations. However, the average size of the corpus callosum is greater in males by about one standard deviation in rats, 0.2 standard deviation in humans, and virtually zero in mice. Furthermore, variations in corpus callosum size are related to brain size and are not sex specific.

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