scholarly journals Serum Concentration of Antibodies to Mumps, but Not Measles, Rubella, or Varicella, Is Associated with Intake of Dietary Fiber in the NHANES, 1999–2004

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 813
Author(s):  
Cynthia B. Van Van Landingham ◽  
Debra R. Keast ◽  
Matthew P. Longnecker

Treatment with prebiotics, a type of dietary fiber, was recently shown to increase antibody concentrations following influenza vaccination in a meta-analysis of clinical trials. In observational epidemiologic studies it is not possible to estimate intake of prebiotics, but quantifying intake of dietary fiber is routine. Our objective was to investigate the potential effect of dietary fiber on immunogenicity. We examined serum antibody concentrations (Measles, Mumps, Rubella, and Varicella) in relation to dietary fiber in more than 12,000 subjects in the U.S. National Health and Nutrition Examination Survey (NHANES) for the period 1999–2004. Data from one (1999–2002) or two (2003–2004) dietary recalls were used to calculate fiber intake. For Mumps the adjusted percentage difference in antibody concentration per interquartile range intake in energy-adjusted dietary fiber was 6.34% (95% confidence interval, 3.10, 9.68). Fiber from grain-based foods was more positively associated than fiber from other fiber-containing food groups. The association was slightly larger among subgroups with higher fiber intake, greater interquartile range in fiber intake, and less measurement error. Furthermore, based on the reliability of the diet recalls in 2003–2004, we calculated that the percentage difference per interquartile increment was substantially attenuated by measurement error. Dietary fiber may have a favorable influence on the immunogenicity of some vaccines or natural infections.

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Bowen Zheng ◽  
Hui Shen ◽  
Hedong Han ◽  
Ting Han ◽  
Yonghong Qin

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15080-e15080 ◽  
Author(s):  
Yu Ma ◽  
Peilin Huang ◽  
Mingyue Hu ◽  
Sunkai Ling ◽  
Yuan Li ◽  
...  

e15080 Background: Epidemiological studies have suggested that intake of dietary fiber is associated with decreased risk of colon cancer, however, these findings are inconsistent in that dietary fiber intake is differentially associated with risks of proximal colon and distal colon cancers. To address this, we conducted a systematic review and meta-analysis. Methods: Pubmed database were searched to identify relevant cohort studies up to December 2016 to examine the association between dietary fiber and risks of proximal colon and distal colon cancers, respectively. A random-effects model was used to compute summary risk estimates. Results: 11 prospective cohort studies were identified and included in the analysis. We observed that the risk of proximal colon cancer was 14% lower among the highest dietary fiber intake compared with the lowest intake (RR = 0.86, 95% confidence interval [CI] = 0.78 to 0.95). A similar result was also found for distal colon cancer (RR = 0.79, 95% CI = 0.71 to 0.87). Conclusions: In current analysis, we show that dietary fiber intake is associated inversely with risks of both proximal and distal colon cancers.


2014 ◽  
Vol 146 (3) ◽  
pp. 689-699.e6 ◽  
Author(s):  
Qiwen Ben ◽  
Yunwei Sun ◽  
Rui Chai ◽  
Aihua Qian ◽  
Bin Xu ◽  
...  

2018 ◽  
Vol 37 (6) ◽  
pp. 1935-1942 ◽  
Author(s):  
Baozhu Wei ◽  
Yang Liu ◽  
Xuan Lin ◽  
Ying Fang ◽  
Jing Cui ◽  
...  

2013 ◽  
Vol 145 (1) ◽  
pp. 113-120.e3 ◽  
Author(s):  
Zhizhong Zhang ◽  
Gelin Xu ◽  
Minmin Ma ◽  
Jie Yang ◽  
Xinfeng Liu

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