scholarly journals Silicon nitride ring resonator biosensors operated at 1310 nm wavelengths via TM-mode grating couplers

Author(s):  
Lucía Castelló-Pedrero ◽  
María I. Gómez-Gómez ◽  
Jaime García-Rupérez ◽  
Amadeu Griol ◽  
Alejandro Martínez

Abstract In this work, we demonstrate a full photonic integrated device for performing highly-sensitive biosensing using silicon nitride ring resonators propagating transverse-magnetic modes at wavelengths around 1310 nm. The device includes fully-etched grating couplers as interfaces with external optical fibres. Sensing experiments are performed in a microfluidic environment using bovine serum albumin and anti-bovine serum albumin as biological agents. In comparison with other photonic platforms based on ring resonators propagating transverse-electric modes, our device shows a better detection performance though the efficiency of the grating couplers can be further improved.

2016 ◽  
Vol 222 ◽  
pp. 1709-1715 ◽  
Author(s):  
Chuanxin He ◽  
Minsui Xie ◽  
Fei Hong ◽  
Xiaoyan Chai ◽  
Hongwei Mi ◽  
...  

2002 ◽  
Vol 723 ◽  
Author(s):  
Amanda J. Haes ◽  
Richard P. Van Duyne

AbstractNanosphere lithography (NSL) derived triangular Ag nanoparticles were used to create an extremely sensitive and specific optical biological and chemical nanosensor. Using simple UV-vis spectroscopy, biotinylated surface-confined Ag nanoparticles were used to detect streptavidin down to one picomolar concentrations. The system was tested for nonspecific binding interactions with bovine serum albumin and was found to display virtually no adverse results. The extremely sensitive and selective response of the Ag nanoparticle sensor indicates an exciting use for biological and chemical sensing.


2014 ◽  
Vol 104 (4) ◽  
pp. 043705 ◽  
Author(s):  
Vikash Sharma ◽  
Ajay Kumar ◽  
Prasun Ganguly ◽  
A. M. Biradar

2015 ◽  
Vol 642 ◽  
pp. 125-129
Author(s):  
Jing Ling Zhou ◽  
Chun Shu Zhai ◽  
Su Yun Yang ◽  
Shu Qian Wu ◽  
Guo Qing Wu ◽  
...  

To research the friction and wear of silicon nitride ceramic with bovine serum albumin lubricant, the tribological properties of silicon nitride ceramic against stainless steel were investigated on CETR UMT-2 under lubrication of bovine serum albumin, deionized water, physiological saline and physiological saline mixed with bovine serum albumin. The worn surfaces of silicon nitride ceramic ball and stainless steel pin were examined with a digital microscope (VHX-2000). The friction coefficients of steady state are 0.26, 0.35, 0.69 and 0.8 under bovine serum albumin, physiological saline mixed with bovine serum albumin, physiological saline and deionized water. The lowest friction coefficient of steady state is 0.26 which is under lubrication of bovine serum albumin. The highest friction coefficient is 0.8 under the lubrication of deionized water. The measured worn areas of silicon nitride ceramic balls are 1282.3μm2, 1898.6μm2, 2753.9μm2 and 3645.7μm2 under bovine serum albumin, physiological saline mixed with bovine serum albumin, physiological saline and deionized water. The smallest worn area of silicon nitride ceramic ball is 1282.3μm2 which is measured under the lubrication of bovine serum albumin. The highest worn area of silicon nitride ceramic ball is 3645.7μm2 which was measured under the lubrication of deionized water. The same wear mechanism of silicon nitride ceramic ball had been found under the lubrication of bovine serum albumin, deionized water, physiological saline and physiological saline mixed with bovine serum albumin. The depth of scratches of worn surface of silicon nitride ceramic ball lubricated with BSA is 3μm which are the shallowest.


2015 ◽  
Vol 642 ◽  
pp. 99-103 ◽  
Author(s):  
J.L. Zhou ◽  
Su Yun Yang ◽  
C.S. Zhai ◽  
Z.M. Cheng ◽  
Shu Qian Wu ◽  
...  

The friction coefficient of tribology pair between silicon nitride ceramic and stainless steel was researched with bovine serum albumin, saline and water lubricants. The coefficient of friction of silicon nitride in bovine serum albumin is lower than those in saline and water. Using digital microscope, the worn surfaces of silicon nitride and stainless steel were viewed. The groove depths of worn stainless steel surface were measured. The depth with bovine serum albumin is shallower than those in saline and water. The results showed that ceramic in bovine serum albumin has good tribological characteristic. This research provides the reference for the development of ceramic artificial joint.


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