scholarly journals Fast prototyping of a local fuzzy search system for decision support and retraining of hospital staff during pandemic

2020 ◽  
Author(s):  
Evgeny Bakin ◽  
Oksana Stanevich ◽  
Dmitry Lioznov ◽  
Alexander Kulikov
Keyword(s):  
Decision Support ◽  
Medical Center ◽  
Health Information System ◽  
Hospital Staff ◽  
Machine Learning Algorithms ◽  
Local Health ◽  
Search System ◽  
R Programming Language ◽  
Fuzzy Search ◽  
R Programming

Abstract Purpose. COVID-19 pandemic has shown an urgent need for decision support systems to help doctors in a period of stress and uncertainty. However, significant differences in hospital conditions, as well as skepticism of doctors about machine learning algorithms, limit their introduction into clinical practice. Our goal was to test and apply a principle of "patient-like-mine" decision support in rapidly changing conditions of a pandemic.Methods. In the developed system we implemented a fuzzy search that allows a doctor to compare their medical case with similar cases recorded since the beginning of the pandemic in their medical center. Various distance metrics were tried for obtaining clinically relevant search results. With the use of R programming language, we designed the first version of the system in approximately a week. A set of features for the comparison of the cases was selected with the use of random forest algorithm implemented in Caret. Shiny package was chosen for the design of GUI. Results. The deployed tool allowed doctors to quickly estimate the current conditions of their patients by means of studying the most similar previous cases stored in the local health information system. Extensive testing of the system during the first wave of COVID-19 has shown that this approach helps not only to draw a conclusion about the optimal treatment tactics and to train medical staff in real-time but also to optimize patients’ individual testing plans.Conclusions. This project points to the possibility of rapid prototyping and effective usage of "patient-like-mine" search systems at the time of a pandemic caused by a poorly known pathogen.

scholarly journals Fast prototyping of a local fuzzy search system for decision support and retraining of hospital staff during pandemic

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Evgeny A. Bakin ◽  
Oksana V. Stanevich ◽  
Daria M. Danilenko ◽  
Dmitry A. Lioznov ◽  
Alexander N. Kulikov
Keyword(s):  
Decision Support ◽  
Medical Center ◽  
Health Information System ◽  
Hospital Staff ◽  
Machine Learning Algorithms ◽  
Local Health ◽  
Search System ◽  
R Programming Language ◽  
Fuzzy Search ◽  
R Programming

Abstract Purpose The COVID-19 pandemic showed an urgent need for decision support systems to help doctors at a time of stress and uncertainty. However, significant differences in hospital conditions, as well as skepticism of doctors about machine learning algorithms, limit their introduction into clinical practice. Our goal was to test and apply the principle of ”patient-like-mine” decision support in rapidly changing conditions of a pandemic. Methods In the developed system we implemented a fuzzy search that allows a doctor to compare their medical case with similar cases recorded in their medical center since the beginning of the pandemic. Various distance metrics were tried for obtaining clinically relevant search results. With the use of R programming language, we designed the first version of the system in approximately a week. A set of features for the comparison of the cases was selected with the use of random forest algorithm implemented in Caret. Shiny package was chosen for the design of GUI. Results The deployed tool allowed doctors to quickly estimate the current conditions of their patients by means of studying the most similar previous cases stored in the local health information system. The extensive testing of the system during the first wave of COVID-19 showed that this approach helps not only to draw a conclusion about the optimal treatment tactics and to train medical staff in real-time but also to optimize patients’ individual testing plans. Conclusions This project points to the possibility of rapid prototyping and effective usage of ”patient-like-mine” search systems at the time of a pandemic caused by a poorly known pathogen.

scholarly journals Associations of physicians’ prescribing experience, work hours, and workload with prescription errors

2020 ◽  
Author(s):  
Ilona Leviatan ◽  
Bernice Oberman ◽  
Eyal Zimlichman ◽  
Gideon Y Stein
Keyword(s):  
Decision Support ◽  
Work Experience ◽  
Large Scale ◽  
Medical Center ◽  
Work Conditions ◽  
Machine Learning Algorithms ◽  
Computerized Decision Support ◽  
Prescription Errors ◽  
Specific Medication ◽  
Work Shifts

Abstract Objective We aimed to assess associations of physician’s work overload, successive work shifts, and work experience with physicians’ risk to err. Materials and Methods This large-scale study included physicians who prescribed at least 100 systemic medications at Sheba Medical Center during 2012–2017 in all acute care departments, excluding intensive care units. Presumed medication errors were flagged by a high-accuracy computerized decision support system that uses machine-learning algorithms to detect potential medication prescription errors. Physicians’ successive work shifts (first or only shift, second, and third shifts), workload (assessed by the number of prescriptions during a shift) and work-experience, as well as a novel measurement of physicians’ prescribing experience with a specific drug, were assessed per prescription. The risk to err was determined for various work conditions. Results 1 652 896 medical orders were prescribed by 1066 physicians; The system flagged 3738 (0.23%) prescriptions as erroneous. Physicians were 8.2 times more likely to err during high than normal-low workload shifts (5.19% vs 0.63%, P < .0001). Physicians on their third or second successive shift (compared to a first or single shift) were more likely to err (2.1%, 1.8%, and 0.88%, respectively, P < .001). Lack of experience in prescribing a specific medication was associated with higher error rate (0.37% for the first 5 prescriptions vs 0.13% after over 40, P < .001). Discussion Longer hours and less experience in prescribing a specific medication increase risk of erroneous prescribing. Conclusion Restricting successive shifts, reducing workload, increasing training and supervision, and implementing smart clinical decision support systems may help reduce prescription errors.

Derivation of Respiratory Metrics in Health and Asthma; Machine Learning Methodology (Preprint)

2020 ◽  
Author(s):  
Joseph Prinable ◽  
Peter Jones ◽  
David Boland ◽  
Alistair McEwan ◽  
Cindy Thamrin
Keyword(s):  
Machine Learning ◽  
Short Term Memory ◽  
Reference Signal ◽  
Machine Learning Algorithms ◽  
Training Dataset ◽  
Local Health ◽  
Strongly Correlated ◽  
Human Research Ethics ◽  
Expiration Time ◽  
Wide Variability

BACKGROUND The ability to continuously monitor breathing metrics may have indications for general health as well as respiratory conditions such as asthma. However, few studies have focused on breathing due to a lack of available wearable technologies. OBJECTIVE Examine the performance of two machine learning algorithms in extracting breathing metrics from a finger-based pulse oximeter, which is amenable to long-term monitoring. METHODS Pulse oximetry data was collected from 11 healthy and 11 asthma subjects who breathed at a range of controlled respiratory rates. UNET and Long Short-Term memory (LSTM) algorithms were applied to the data, and results compared against breathing metrics derived from respiratory inductance plethysmography measured simultaneously as a reference. RESULTS The UNET vs LSTM model provided breathing metrics which were strongly correlated with those from the reference signal (all p<0.001, except for inspiratory:expiratory ratio). The following relative mean bias(95% confidence interval) were observed: inspiration time 1.89(-52.95, 56.74)% vs 1.30(-52.15, 54.74)%, expiration time -3.70(-55.21, 47.80)% vs -4.97(-56.84, 46.89)%, inspiratory:expiratory ratio -4.65(-87.18, 77.88)% vs -5.30(-87.07, 76.47)%, inter-breath intervals -2.39(-32.76, 27.97)% vs -3.16(-33.69, 27.36)%, and respiratory rate 2.99(-27.04 to 33.02)% vs 3.69(-27.17 to 34.56)%. CONCLUSIONS Both machine learning models show strongly correlation and good comparability with reference, with low bias though wide variability for deriving breathing metrics in asthma and health cohorts. Future efforts should focus on improvement of performance of these models, e.g. by increasing the size of the training dataset at the lower breathing rates. CLINICALTRIAL Sydney Local Health District Human Research Ethics Committee (#LNR\16\HAWKE99 ethics approval).

scholarly journals Development of Machine Learning Models for Prediction of Smoking Cessation Outcome

2021 ◽  
Vol 18 (5) ◽  
pp. 2584
Author(s):  
Cheng-Chien Lai ◽  
Wei-Hsin Huang ◽  
Betty Chia-Chen Chang ◽  
Lee-Ching Hwang
Keyword(s):  
Machine Learning ◽  
Smoking Cessation ◽  
Success Rate ◽  
Prediction Models ◽  
Smoking Status ◽  
Medical Center ◽  
Machine Learning Algorithms ◽  
Classification And Regression Tree ◽  
Support Vector ◽  
Smoking Cessation Outcome

Predictors for success in smoking cessation have been studied, but a prediction model capable of providing a success rate for each patient attempting to quit smoking is still lacking. The aim of this study is to develop prediction models using machine learning algorithms to predict the outcome of smoking cessation. Data was acquired from patients underwent smoking cessation program at one medical center in Northern Taiwan. A total of 4875 enrollments fulfilled our inclusion criteria. Models with artificial neural network (ANN), support vector machine (SVM), random forest (RF), logistic regression (LoR), k-nearest neighbor (KNN), classification and regression tree (CART), and naïve Bayes (NB) were trained to predict the final smoking status of the patients in a six-month period. Sensitivity, specificity, accuracy, and area under receiver operating characteristic (ROC) curve (AUC or ROC value) were used to determine the performance of the models. We adopted the ANN model which reached a slightly better performance, with a sensitivity of 0.704, a specificity of 0.567, an accuracy of 0.640, and an ROC value of 0.660 (95% confidence interval (CI): 0.617–0.702) for prediction in smoking cessation outcome. A predictive model for smoking cessation was constructed. The model could aid in providing the predicted success rate for all smokers. It also had the potential to achieve personalized and precision medicine for treatment of smoking cessation.

scholarly journals Microrisk Lab: an online freeware for predictive microbiology

2020 ◽  
Author(s):  
Yangtai Liu ◽  
Xiang Wang ◽  
Baolin Liu ◽  
Qingli Dong
Keyword(s):  
Parameter Estimation ◽  
Bacterial Growth ◽  
Model Simulation ◽  
Parameter Determination ◽  
Predictive Microbiology ◽  
Isothermal Conditions ◽  
R Programming Language ◽  
Behavior Simulation ◽  
R Programming ◽  
And Behavior

AbstractMicrorisk Lab was designed as an interactive modeling freeware to realize parameter estimation and model simulation in predictive microbiology. This tool was developed based on the R programming language and ‘Shinyapps.io’ server, and designed as a fully responsive interface to the internet-connected devices. A total of 36 peer-reviewed models were integrated for parameter estimation (including primary models of bacterial growth/ inactivation under static and non-isothermal conditions, secondary models of specific growth rate, and competition models of two-flora growth) and model simulation (including integrated models of deterministic or stochastic bacterial growth/ inactivation under static and non-isothermal conditions) in Microrisk Lab. Each modeling section was designed to provide numerical and graphical results with comprehensive statistical indicators depending on the appropriate dataset and/ or parameter setting. In this research, six case studies were reproduced in Microrisk Lab and compared in parallel to DMFit, GInaFiT, IPMP 2013/ GraphPad Prism, Bioinactivation FE, and @Risk, respectively. The estimated and simulated results demonstrated that the performance of Microrisk Lab was statistically equivalent to that of other existing modeling system in most cases. Microrisk Lab allowed for uniform user experience to implement microbial predictive modeling by its friendly interfaces, high-integration, and interconnectivity. It might become a useful tool for the microbial parameter determination and behavior simulation. Non-commercial users could freely access this application at https://microrisklab.shinyapps.io/english/.

scholarly journals AI for augmenting human judgement in Business Processes Management

2021 ◽  
Vol 201 (3) ◽  
pp. 507-518
Author(s):  
Łukasz Osuszek ◽  
Stanisław Stanek
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Decision Support ◽  
Business Processes ◽  
Workflow Management ◽  
Organizational Memory ◽  
Machine Learning Algorithms ◽  
Analytical Models ◽  
Case Based Reasoning ◽  
Historical Case

The paper outlines the recent trends in the evolution of Business Process Management (BPM) – especially the application of AI for decision support. AI has great potential to augment human judgement. Indeed, Machine Learning might be considered as a supplementary and complimentary solution to enhance and support human productivity throughout all aspects of personal and professional life. The idea of merging technologies for organizational learning and workflow management was first put forward by Wargitsch. Herein, completed business cases stored in an organizational memory are used to configure new workflows, while the selection of an appropriate historical case is supported by a case-based reasoning component. This informational environment has been recognized in the world as being effective and has become quite common because of the significant increase in the use of artificial intelligence tools. This article discusses also how automated planning techniques (one of the oldest areas in AI) can be used to enable a new level of automation and processing support. The authors of the article decided to analyse this topic and discuss the scientific state of the art and the application of AI in BPM systems for decision-making support. It should be noted that readily available software exists for the needs of the development of such systems in the field of artificial intelligence. The paper also includes a unique case study with production system of Decision Support, using controlled machine learning algorithms to predictive analytical models.

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