DNA Repair and Ethnic Differences in Prostate Cancer Risk

2008 ◽  
Author(s):  
Radoslav Goldman
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Ethnic Differences ◽  
Prostate Cancer Risk

259: Dna-Repair Genetic Polymorphisms and Prostate Cancer Risk

2005 ◽  
Vol 173 (4S) ◽  
pp. 71-71
Author(s):  
Peter E. Clark ◽  
M. Craig Hall ◽  
Kristin L. Lockett ◽  
Jianfeng Xu ◽  
Sigun L. Zheng ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Genetic Polymorphisms ◽  
Prostate Cancer Risk

scholarly journals Relationship between XPD, RAD51, and APEX1 DNA repair genotypes and prostate cancer risk in the male population of Rio de Janeiro, Brazil

2017 ◽  
Vol 40 (4) ◽  
pp. 751-758 ◽  
Author(s):  
Ana Sheila Cypriano ◽  
Gilda Alves ◽  
Antonio Augusto Ornellas ◽  
José Scheinkman ◽  
Renata Almeida ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Rio De Janeiro ◽  
Prostate Cancer Risk ◽  
Male Population

scholarly journals Racial/ethnic differences in lifestyle-related factors and prostate cancer risk: the Multiethnic Cohort Study

2015 ◽  
Vol 26 (10) ◽  
pp. 1507-1515 ◽  
Author(s):  
Song-Yi Park ◽  
Christopher A. Haiman ◽  
Iona Cheng ◽  
Sungshim Lani Park ◽  
Lynne R. Wilkens ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cohort Study ◽  
Cancer Risk ◽  
Ethnic Differences ◽  
Prostate Cancer Risk ◽  
Related Factors ◽  
Multiethnic Cohort ◽  
Racial Ethnic

scholarly journals No association between variant DNA repair genes and prostate cancer risk among men of African descent

The Prostate ◽  
2009 ◽  
pp. n/a-n/a
Author(s):  
Nicole A. Lavender ◽  
Oyeyemi O. Komolafe ◽  
Marnita Benford ◽  
Guy Brock ◽  
Jason H. Moore ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
African Descent ◽  
Prostate Cancer Risk ◽  
Dna Repair Genes ◽  
Repair Genes

scholarly journals Polymorphisms of Homologous RecombinationRAD51,RAD51B,XRCC2, andXRCC3Genes and the Risk of Prostate Cancer

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Maria Nowacka-Zawisza ◽  
Ewelina Wiśnik ◽  
Andrzej Wasilewski ◽  
Milena Skowrońska ◽  
Ewa Forma ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Cancer Susceptibility ◽  
Critical Role ◽  
Prostate Cancer Risk ◽  
Nucleotide Polymorphisms ◽  
Repair Capacity ◽  
Dna Repair Capacity ◽  
Risk Of Cancer

Genetic polymorphisms in DNA repair genes may induce individual variations in DNA repair capacity, which may in turn contribute to the risk of cancer developing. Homologous recombination repair (HRR) plays a critical role in maintaining chromosomal integrity and protecting against carcinogenic factors. The aim of the present study was to evaluate the relationship between prostate cancer risk and the presence of single nucleotide polymorphisms (SNPs) in the genes involved in HRR, that is,RAD51(rs1801320 and rs1801321),RAD51B(rs10483813 and rs3784099),XRCC2(rs3218536), andXRCC3(rs861539). Polymorphisms were analyzed by PCR-RFLP and Real-Time PCR in 101 patients with prostate adenocarcinoma and 216 age- and sex-matched controls. A significant relationship was detected between theRAD51gene rs1801320 polymorphism and increased prostate cancer risk. Our results indicate that theRAD51gene rs1801320 polymorphism may contribute to prostate cancer susceptibility in Poland.

Sign in / Sign up

Export Citation Format

Share Document