Exploring Neurofibromin Function in a Yeast Model of NF1

2009 ◽  
Author(s):  
Aaron Gitler
Keyword(s):  
Yeast Model

Ultrastructure of the effect of T-514 obtained from Karwinskia humboldtiana on assembly and integrity of yeast's peroxisomes

1991 ◽  
Vol 49 ◽  
pp. 136-137
Author(s):  
J. Sepulveda-Saavedra ◽  
I. Vander-Klei ◽  
M. Venhuis ◽  
Y. Piñeyro-Lopez
Keyword(s):  
Culture Conditions ◽  
Toxic Effects ◽  
Candida Boidinii ◽  
Central Mexico ◽  
Poisonous Plant ◽  
Biological Behaviour ◽  
Enzyme Content ◽  
Fat Deposits ◽  
Yeast Model

Karwinskia humboldtiana is a poisonous plant that grows in semi desertic areas in north and central México. It produces several substances with different toxic effects. One of them designated T-514 damages severely the lung, kidney and liver, producing in the hepatoeyte large intracellular fat deposits and necrosis. Preliminary observations demonstrated that three is a decrease in the amount of peroxisomes in the hepatocytes of experimentally intoxicated rats and monkeys. To study the effect exerted by the T-514 on peroxisomes, a yeast model was selected, thus, three species: Saccha romices cerevisiae, Ilansenula polymorpha and Candida boidinii were used, because there is information concerning their peroxisome's morphology, enzyme content, biological behaviour under different culture conditions and biogenesis.

scholarly journals Heterozygous mutations cause genetic instability in a yeast model of cancer evolution

Nature ◽  
2019 ◽  
Vol 566 (7743) ◽  
pp. 275-278 ◽  
Author(s):  
Miguel C. Coelho ◽  
Ricardo M. Pinto ◽  
Andrew W. Murray
Keyword(s):  
Genetic Instability ◽  
Cancer Evolution ◽  
Yeast Model

scholarly journals The yeast model system as a tool towards the understanding of apoptosis regulation by sphingolipids

2013 ◽  
Vol 14 (1) ◽  
pp. 160-178 ◽  
Author(s):  
António Rego ◽  
Dário Trindade ◽  
Susana R. Chaves ◽  
Stéphen Manon ◽  
Vítor Costa ◽  
...  
Keyword(s):  
Model System ◽  
Apoptosis Regulation ◽  
Yeast Model

scholarly journals Phosphorylation Modulates Clearance of Alpha-Synuclein Inclusions in a Yeast Model of Parkinson's Disease

PLoS Genetics ◽  
2014 ◽  
Vol 10 (5) ◽  
pp. e1004302 ◽  
Author(s):  
Sandra Tenreiro ◽  
Madalena M. Reimão-Pinto ◽  
Pedro Antas ◽  
José Rino ◽  
Donata Wawrzycka ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Alpha Synuclein ◽  
Yeast Model

scholarly journals Yeast model for evaluating the pathogenic significance of SDHB, SDHC and SDHD mutations in PHEO-PGL syndrome

2012 ◽  
Vol 22 (4) ◽  
pp. 804-815 ◽  
Author(s):  
E. Panizza ◽  
T. Ercolino ◽  
L. Mori ◽  
E. Rapizzi ◽  
M. Castellano ◽  
...  
Keyword(s):  
Yeast Model

scholarly journals A predictive dynamic yeast model based on component, energy, and electron carrier balances

2020 ◽  
Vol 117 (9) ◽  
pp. 2728-2740 ◽  
Author(s):  
Angéla La ◽  
Huan Du ◽  
Behnam Taidi ◽  
Patrick Perré
Keyword(s):  
Electron Carrier ◽  
Model Based ◽  
Yeast Model
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