Role of Immunohistochemistry in trephine biopsies of Bone Marrow: A 5-year Retrospective study from a tertiary care hospital

Background: The objective of the study was to assess the role of corticosteroid given preoperatively in decreasing intraoperative bleeding during functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis.Methods: This is a retrospective study conducted in a tertiary care hospital for patients undergoing FESS for chronic rhinosinusitis from January 2016 to December 2016. In this study 120 patients of FESS were enrolled. Their data was analyzed for preoperative corticosteroid given and intraoperative grade of bleeding. Results: There were 62 patients out of 120 who received preoperative corticosteroid. Among these 41 had grade 0-1 bleeding and 21 had grade 2-5 bleeding. Similarly in non-corticosteroid group 30 had grade 0-1 bleeding and 28 had grade 2-5 bleeding. Based on these p values was calculated using fisher exact test which showed that to be non-significant.Conclusions: Preoperative corticosteroids do not have control on intraoperative bleeding during FESS. They help in reducing the size of polyp and thus more effective in cases of CRSwNP.

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A TWO YEARS STUDY OF SHOWCASING THE ROLE OF BONE MARROW ASPIRATION IN DIAGNOSING THE SPECTRUM OF HAEMATOLOGICAL DISORDERS IN A TERTIARY CARE HOSPITAL

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2016/1491 ◽

2016 ◽

Vol 5 (89) ◽

pp. 6594-6597

Author(s):

Shashidhar M R ◽

Kiran H S

Keyword(s):

Bone Marrow ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Bone Marrow Aspiration ◽

Care Hospital ◽

Haematological Disorders

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The role of autologous conchal cartilage in ossiculoplasty during canal wall down mastoidectomy

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20175611 ◽

2017 ◽

Vol 4 (1) ◽

pp. 123

Author(s):

Roshan Jalisatgi ◽

Santosh S. Garag ◽

Arunkumar J. S.

Keyword(s):

Developing Countries ◽

Retrospective Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Canal Wall ◽

Hearing Outcome ◽

Canal Wall Down ◽

Canal Wall Down Mastoidectomy

Background: This study was done to evaluate the hearing outcome in patients undergoing ossiculoplasty using autograft cartilage in canal wall down surgery for cholesteatoma.Methods: This is a retrospective study. This was conducted in a tertiary care hospital from January 2011 to January 2014. This study included 54 patients who underwent canal wall down mastoidectomy with tympanoplasty during this period. Results: Preoperative and postoperative ABG for short columella were 23.13 dB (±11.21) and 12.66 dB (±8.92) respectively. Preoperative and post-operative ABG for long columella were 36.96 dB (±6.73) and 24.77 dB (±10.36) respectively. This is statistically significant.Conclusions: The use of autologous cartilage in ossiculoplasty during canal wall down mastoidectomy gives excellent hearing gain. It is also a cheaper option which is financially feasible in developing countries.

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TO DETERMINE THE ROLE OF CA125 IN THE DIAGNOSIS OF ACUTE APPENDICITIS

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i7.1276 ◽

2020 ◽

Vol 4 (7) ◽

Author(s):

Vinod Kumar ◽

Bhupen Songra ◽

Richa Jain ◽

Deeksha Mehta

Keyword(s):

Acute Appendicitis ◽

Clinical Diagnosis ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Ca 125 ◽

Care Hospital ◽

Serum Samples ◽

Roc Curve Analysis ◽

Surgery Department

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.

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