scholarly journals Primary Thyroid Lymphoma

2020 ◽  
Vol 7 (6) ◽  
pp. C74-77
Author(s):  
Sripriya Krishnan ◽  
I V Renuka ◽  
C H Ramya ◽  
Harshitha .
Keyword(s):  
Rare Condition ◽  
Histopathological Diagnosis ◽  
Neck Swelling ◽  
Thyroid Lymphoma ◽  
Primary Thyroid Lymphoma ◽  
Thyroid Malignancies ◽  
Loss Of Appetite ◽  
Hodgkin's Lymphomas ◽  
Secondary Lymphoma ◽  
Extensive Surgery

Primary thyroid lymphoma (PTL) is a rare condition and accounts for 5% of all thyroid malignancies. They constitute less than 2 % of all lymphomas. Most PTL’s are non-Hodgkin's lymphomas. It is clinically essential to discriminate between primary or secondary lymphoma of the thyroid as the treatment and prognosis varies. It commonly occurs in women in their sixth and seventh decade. Primary thyroid lymphoma is quite curable without the need for extensive surgery if diagnosed early. We present such a case of a 60- year old female patient presenting with complaints of neck swelling with loss of appetite and dysphagia. Histopathological diagnosis confirmed Primary thyroid lymphoma of B cell origin which was confirmed by immunohistochemistry.

scholarly journals Emergency Thyroidectomy: A Rare Case

2014 ◽  
Vol 6 (1) ◽  
pp. 47-49
Author(s):  
Nitin Gupta
Keyword(s):  
Emergency Department ◽  
Thyroid Gland ◽  
Rare Case ◽  
Rare Tumor ◽  
Neck Swelling ◽  
Thyroid Lymphoma ◽  
Primary Thyroid Lymphoma ◽  
Thyroid Malignancies

ABSTRACT Primary thyroid lymphoma is a rare tumor of the thyroid gland, accounting for 1 to 2% of all thyroid malignancies. The mainstay of treatment for lymphamas is chemoradiation but thyroidectomy is required for patients with large thyroid gland presenting with obstructive symptoms, such as stridor. We present here such a case of a 54-year-old female who had presented in the emergency department of our institute with a huge neck swelling and stridor. Emergency thyroidectomy was done to relieve stridor. How to cite this article Gupta N, Varshney S. Emergency Thyroidectomy: A Rare Case. Int J Otorhinolaryngol Clin 2014;6(1):47-49.

Association of Hashimoto’s Thyroiditis and Burkitt Lymphoma: A Rare Condition to Be Considered

Praxis ◽  
2021 ◽  
Vol 110 (14) ◽  
pp. 812-815
Author(s):  
Dea Degabriel ◽  
Alberto Cerutti ◽  
Laura Caramanica ◽  
Alessandro Viganò ◽  
and Tanja Fusi-Schmidhauser
Keyword(s):  
Weight Loss ◽  
Case Report ◽  
Hashimoto’S Thyroiditis ◽  
Rare Condition ◽  
Hashimoto's Thyroiditis ◽  
Low Grade ◽  
Thyroid Lymphoma ◽  
Thyroid Mass ◽  
Primary Thyroid Lymphoma ◽  
Rule Out

Abstract. We present the case of a 72-year-old woman who was diagnosed with Hashimoto’s thyroiditis and who developed a low-grade fever, fatigue, and weight loss that prompted to perform a thyroid biopsy to rule out an underlying primary thyroid lymphoma. This case report offers the opportunity to review the association between Hashimoto’s thyroiditis and primary thyroid lymphoma. Furthermore, it underlines the importance of considering the diagnosis of lymphoma when a thyroid mass is found in patients with an underlying Hashimoto’s disease, as the timely management is essential for survival with this rare thyroid condition.

scholarly journals Fluorodeoxyglucose positron emission tomography-computed tomography base response assessment in primary thyroid lymphoma

2020 ◽  
Vol 6 (12) ◽  
pp. 2313
Author(s):  
Tarun Kumar Jain ◽  
Anushree Punia ◽  
Shikha Dhal ◽  
Guman Singh ◽  
Hemant Malhotra ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Thyroid Gland ◽  
Emission Tomography ◽  
Fluorodeoxyglucose Positron Emission Tomography ◽  
Thyroid Lymphoma ◽  
Positron Emission ◽  
Pet Ct ◽  
Primary Thyroid Lymphoma ◽  
Thyroid Malignancies ◽  
Fluorodeoxyglucose Positron Emission

<p class="abstract">Isolated primary thyroid lymphoma and lesion in the thyroid gland presenting as a lymphoma, both are uncommon entities. This subgroup of thyroid malignancies is managed in different ways as compared to common thyroid malignancies. A 63-year-old male diagnosed as non-Hodgkin’s lymphoma of the thyroid gland underwent for F-18 fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT). It revealed isolated FDG avid soft tissue mass in left lobe of thyroid gland. After two and six cycles of chemotherapy, PET-CT was perfomed and response assessed in Deauville scores.  </p>

Synchronous primary diffuse large B-cell lymphoma and papillary thyroid carcinoma: a case report highlighting “Lymphoma first approach”

2021 ◽  
pp. 1-10
Author(s):  
Rahim Dhanani ◽  
Ambreen Abdullah Unar ◽  
Muhammad Hassan Danish ◽  
Hamdan Ahmed Pasha ◽  
Ummiya Tahir ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Cell Lymphoma ◽  
Rare Condition ◽  
B Cell Lymphoma ◽  
Rare Entity ◽  
Papillary Thyroid ◽  
Thyroid Lymphoma ◽  
Large B Cell Lymphoma ◽  
Thyroid Malignancies

Papillary thyroid carcinoma (PTC) is the most common type of all thyroid carcinomas and accounts for up to 90% of all thyroid malignancies. It is the most indolent form of the disease and has an excellent prognosis. On the other hand, Primary thyroid lymphoma (PTL) is a rare entity accounting for only about 1% to 5% of all thyroid malignancies and only 2% of extranodal lymphomas. Synchronous PTC and PTL is a very rare condition and only a few cases have been reported in the literature up till now. We report one such case in a 52-year-old lady who was referred to us with goiter and progressively increasing difficulty in breathing. Keywords: Synchronous thyroid malignancies, Papillary thyroid carcinoma, Lymphoma Continuous...

scholarly journals Primary thyroid lymphoma: a comprehensive summary of two cases

2015 ◽  
Vol 1 (3) ◽  
pp. 177
Author(s):  
Sonam Sharma ◽  
Devashis Mandal ◽  
Amit K. Yadav ◽  
Ashish K. Mandal
Keyword(s):  
Early Recognition ◽  
Cervical Lymphadenopathy ◽  
Neck Mass ◽  
Thyroid Lymphoma ◽  
Anterior Neck ◽  
High Clinical Suspicion ◽  
Diagnostic Modalities ◽  
Rare Malignancy ◽  
Thyroid Malignancies ◽  
Extensive Surgery

<p class="abstract"><span lang="EN-US">Thyroid lymphoma occurs rarely; constituting approximately 1-5% of all thyroid malignancies. Two cases of thyroid lymphoma are presented herewith. Both the patients were elderly females who presented with a rapidly enlarging anterior neck mass without cervical lymphadenopathy, leading to compressive symptoms like dysphagia, stridor and dyspnoea. Thyroid lymphoma is a great diagnostic and therapeutic challenge which requires high clinical suspicion with rapid and accurate diagnostic modalities to detect it as early recognition of this rare malignancy can lead to timely intervention and avoid morbidity associated with extensive surgery as chemotherapy and radiation are the mainstays of its treatment.</span></p>

scholarly journals Primary Thyroid Lymphoma in an Adolescent with Hashimoto’s Thyroiditis and Congenital Deafness

2020 ◽  
pp. 1-5
Author(s):  
Yeleni Eelen ◽  
Jaques van Heerden ◽  
Joris Verlooy ◽  
Koen Norga ◽  
Thomas Tousseyn ◽  
...  
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Usher Syndrome ◽  
B Cell Lymphoma ◽  
Paediatric Population ◽  
Hashimoto's Thyroiditis ◽  
Congenital Deafness ◽  
Thyroid Lymphoma ◽  
Thyroid Mass ◽  
Primary Thyroid Lymphoma ◽  
Thyroid Malignancies

Background: Primary thyroid lymphoma is extremely rare in children and adolescents. The diagnosis of thyroid malignancies is often made secondary to other thyroid pathologies including Hashimoto’s thyroiditis (HT). Case Presentation: This case describes a 14-year-old girl with a background of HT and congenital deafness that presented with a rapidly enlarging multinodular thyroid mass. She underwent a total thyroidectomy and a diffuse, large B-cell lymphoma was diagnosed on pathology. Discussion: Primary thyroid disease is an extremely rare disease in childhood, usually presenting as a rapidly enlarging goitre. The correlation between Hashimoto’s thyroiditis and primary thyroid lymphoma is well-established in adults but has not been verified in the paediatric population. Our patient also has βthalassemia and Usher syndrome, however, no correlation between these and primary thyroid lymphoma could be found in the literature. Conclusion: It is important to include malignancy in the differential diagnosis of thyroid enlargement or unexplained symptoms, especially in the presence of syndromes. Further research into the relation between lymphomas and HT in the paediatric population is needed.

Primary thyroid lymphoma: about two cases

2019 ◽  
Author(s):  
Bouchenna Amira ◽  
Kharkhache Badreddine ◽  
Brakni lila ◽  
Ould Kablia Nadjet ◽  
Tibouk Abdelghani ◽  
...  
Keyword(s):  
Thyroid Lymphoma ◽  
Primary Thyroid Lymphoma

scholarly journals Extranodal NK/T-cell lymphoma in Tunisia: clinicopathological features, immunophenotype and EBV infection

2019 ◽  
Vol 31 (1) ◽  
Author(s):  
Nabiha Missaoui ◽  
Sarra Mestiri ◽  
Aida Bouriga ◽  
Nihed Abdessayed ◽  
Mouna Belakhdher ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
T Cell ◽  
Granzyme B ◽  
Clinicopathological Features ◽  
Histopathological Diagnosis ◽  
Ebv Infection ◽  
Nk T Cell ◽  
Epstein Barr ◽  
Hodgkin's Lymphomas

Abstract Background Extranodal NK/T-cell lymphomas (ENKTL) are rare non-Hodgkin’s lymphomas with aggressive clinical behavior. ENKTL are frequently associated with the Epstein-Barr virus (EBV). Data on ENKTL in Africa and Arab world are extremely limited. The study investigated the clinicopathological characteristics, EBV infection, and immunophenotype of ENKTL in Tunisia. We conducted a retrospective study of ENKTL. Main clinicopathological features were reported. The expression of CD3, CD4, CD5, CD8, CD20, CD56, CD57, and Granzyme B were analyzed by immunohistochemistry. EBV infection was detected by IHC (LMP-1) and Epstein-Barr encoding region (EBER1/2) in situ hybridization. Results A total of nine ENKTL were identified (mean age of 48 years and male-to-female ratio of 8:1). There were five nasal ENKTL, and the remaining four cases had extranasal involvement (palate, sub-mandibular gland, skin, and soft tissues of the ankle). The histopathology showed a lymphoid and pleomorphic proliferation characterized by images of angiocentrism. Strong and diffuse CD3 expression was observed in all cases. Tumor cells exhibited an expression of CD5 (two cases), CD8 (three cases), CD56 (six cases), CD57 (three cases), and Granzyme B (eight cases). All ENKTL cases were EBV-associated. Overall 5-year survival rate was 57%. Although six ENKTL were diagnosed at early clinical stages, the prognosis was unfavorable and associated with patient death in three cases. Conclusions ENKTL are exceptional in Tunisia with unfavorable outcome. Histopathological diagnosis remains challenging in clinical practice. However, a careful histopathological examination combined with a correct interpretation of immunohistochemistry and in situ hybridization results refines the ENKTL diagnosis.

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