IMMUNOMORPHOLOGY OF PARADOXICAL TUBERCULOSIS WITH CONCURRENT HIV INFECTION AND IRIS, CLINICAL AND DIAGNOSTIC VALUE

Patients with HIV infection often have generalized lymphadenopathy and/or other lymphoid proliferation and are at significantly increased risk for lymphoma. This study retrospectively evaluated the diagnostic value of concurrent nasopharyngeal lesion and lymphadenopathy on positron emission tomography-computed tomography (PET-CT) with fluorine-18 fluorodeoxyglucose (FDG PET-CT) imaging. The eligible cases were from patients with HIV infection and lymphadenopathy and referred for FDG PET-CT to evaluate lymphoma or other malignancies prior to pathological investigation. FDG PET-CT images and interpretation reports were correlated with clinical information and pathological diagnoses. Among 22 eligible patients, FDG avid nasopharyngeal lesions were incidentally noted in 7 on PET-CT imaging, and all had lymphomas diagnosed with subsequent biopsies (6 diffuse large B-cell lymphomas and 1 Hodgkin’s lymphoma). In the remaining 15 patients with adenopathy but no visible nasopharyngeal lesion or uptake on PET-CT imaging, 9 had biopsies and lymphomas were diagnosed in 4. The patients with FDG avid retroperitoneal or intra-abdominal lymphadenopathy had a greater possibility of lymphoma, compared to those with adenopathy localized only in the upper torso. Coexistent FDG avid nasopharyngeal lesion and generalized lymphadenoapthy on PET-CT imaging are indicative of a malignant lymphoma rather than benign lymphproliferative disease or nasopharyngeal carcinoma.

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Diagnostic value of direct fluorescence antibody staining for detecting Pneumocystis jirovecii in expectorated sputum from patients with HIV infection

Medical Mycology ◽

10.1093/mmy/myu002 ◽

2014 ◽

Vol 52 (3) ◽

pp. 326-330 ◽

Cited By ~ 10

Author(s):

Pyoeng Gyun Choe ◽

Yoo Min Kang ◽

Gayeon Kim ◽

Wan Beom Park ◽

Sang Won Park ◽

...

Keyword(s):

Hiv Infection ◽

Diagnostic Value ◽

Pneumocystis Jirovecii ◽

Antibody Staining ◽

Direct Fluorescence ◽

Fluorescence Antibody

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Diagnostic value of specific IgM antibodies in primary HIV infection

AIDS ◽

10.1097/00002030-198802000-00005 ◽

1988 ◽

Vol 2 (1) ◽

pp. 31-36 ◽

Cited By ~ 29

Author(s):

Joep M. A. Lange ◽

John V. Parry ◽

Frank de Wolf ◽

Philip P. Mortimer ◽

Jaap Goudsmit

Keyword(s):

Hiv Infection ◽

Diagnostic Value ◽

Primary Hiv Infection ◽

Igm Antibodies

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CLINICAL AND DIAGNOSTIC VALUE OF ASSESSMENT OF SYSTEMIC INFLAMMATION IN PATIENTS WITH HIV INFECTION

HIV Infection and Immunosuppressive Disorders ◽

10.22328/2077-9828-2018-10-3-64-71 ◽

2018 ◽

Vol 10 (3) ◽

pp. 64-71

Author(s):

A. N. Matuzkova ◽

N. Yu. Pshenichnaya ◽

A. G. Suladze ◽

L. I. Dosyagaeva ◽

T. I. Tverdohlebova ◽

...

Keyword(s):

Hiv Infection ◽

Systemic Inflammation ◽

Solid Phase ◽

Diagnostic Value ◽

Enzyme Linked Immunosorbent Assay ◽

Inflammation Markers ◽

Hiv Patients ◽

Enhanced Production ◽

Flow Cytometric ◽

Cd4 Lymphocytes

Aim of research: to detect a diagnostic value of cumulative clinical assessment of systemic inflammation markers in monitoring a course of HIV infection. Materials and methods. The research is implemented in a sample of 162 HIV patients. The sample is divided into two groups: 1 — receiving HAART (n=88), 2 — not receiving HAART (n=74). The content of lipopolysaccharidebinding protein (LBP), procalcitonin and cytokines (TNF-a, IL-1b, IL-6, IL-8, IL-10, IFN-g, IFN-a) are detected in serum by solid-phase enzyme-linked immunosorbent assay. The number of CD4+-lymphocytes was determined by flow cytometric techniques. Results. Significantly high LBP concentration, in comparison with healthy persons’ indices, is found in both groups of the sample. The content IFN-g and IFN-a is significantly high in majority of HIV patients of the sample regardless of the therapy received. HIV patients with low content of CD4+ lymphocytes, have the indications of more severe systemic inflammation accompanied by enhanced production of anti-endotoxin proteins, and their cytokine profile is characterized by more expressed proinflammatory orientation than in HIV patients with high CD4+ lymphocytes indices. The LBP level may be treated as an indirect criterion of immune suppression intensity in HIV infection.

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Diagnostic Value of Electron Microscopy in Soft Tissue Tumors

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100068096 ◽

1970 ◽

Vol 28 ◽

pp. 220-221

Author(s):

Gerald Fine ◽

Azorides R. Morales

Keyword(s):

Cardiac Myxoma ◽

Osteogenic Sarcoma ◽

Diagnostic Value ◽

Soft Tissue Tumors ◽

Amelanotic Melanoma ◽

Growth Patterns ◽

Light Microscopic Level ◽

Mesenchymal Tumors ◽

Good Agreement

For years the separation of carcinoma and sarcoma and the subclassification of sarcomas has been based on the appearance of the tumor cells and their microscopic growth pattern and information derived from certain histochemical and special stains. Although this method of study has produced good agreement among pathologists in the separation of carcinoma from sarcoma, it has given less uniform results in the subclassification of sarcomas. There remain examples of neoplasms of different histogenesis, the classification of which is questionable because of similar cytologic and growth patterns at the light microscopic level; i.e. amelanotic melanoma versus carcinoma and occasionally sarcoma, sarcomas with an epithelial pattern of growth simulating carcinoma, histologically similar mesenchymal tumors of different histogenesis (histiocytoma versus rhabdomyosarcoma, lytic osteogenic sarcoma versus rhabdomyosarcoma), and myxomatous mesenchymal tumors of diverse histogenesis (myxoid rhabdo and liposarcomas, cardiac myxoma, myxoid neurofibroma, etc.)

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