scholarly journals Policy Evaluation, Randomized Controlled Trials, and External Validity A Systematic Review

2016 ◽  
Author(s):  
JJrg Peters ◽  
Joerg Langbein ◽  
Gareth Roberts
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Policy Evaluation ◽  
External Validity ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Policy evaluation, randomized controlled trials, and external validity—A systematic review

2016 ◽  
Vol 147 ◽  
pp. 51-54 ◽  
Author(s):  
Jörg Peters ◽  
Jörg Langbein ◽  
Gareth Roberts
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Policy Evaluation ◽  
External Validity ◽  
Controlled Trials ◽  
Randomized Controlled

External validity of randomized controlled trials of interventions in venous leg ulceration: A systematic review

2019 ◽  
Vol 27 (6) ◽  
pp. 702-710 ◽  
Author(s):  
Georgina Gethin ◽  
John D. Ivory ◽  
Lauren Connell ◽  
Caroline McIntosh ◽  
Carolina D. Weller
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
External Validity ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Systematic Review and the External Validity of Randomized Controlled Trials in Lupus Nephritis

2018 ◽  
Vol 3 (2) ◽  
pp. 403-411 ◽  
Author(s):  
Angela Pakozdi ◽  
Ravindra Rajakariar ◽  
Debasish Pyne ◽  
Andrea Cove-Smith ◽  
Muhammad Magdi Yaqoob
Keyword(s):  
Systematic Review ◽  
Lupus Nephritis ◽  
Randomized Controlled Trials ◽  
External Validity ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals External validity of randomized controlled trials in older adults, a systematic review

PLoS ONE ◽  
2017 ◽  
Vol 12 (3) ◽  
pp. e0174053 ◽  
Author(s):  
Floor J. van Deudekom ◽  
Iris Postmus ◽  
Danielle J. van der Ham ◽  
Alexander B. Pothof ◽  
Karen Broekhuizen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Randomized Controlled Trials ◽  
External Validity ◽  
Controlled Trials ◽  
Randomized Controlled

Interventions to Reduce Alcohol Harms in Low and Middle Income Countries: a Systematic Review and Meta Analysis

2018 ◽  
Author(s):  
Joao Ricardo Nickenig Vissoci
Keyword(s):  
Systematic Review ◽  
Alcohol Use ◽  
Randomized Controlled Trials ◽  
Brain Stimulation ◽  
Meta Analysis ◽  
World Health ◽  
Controlled Trials ◽  
Middle Income ◽  
Brief Motivational Intervention ◽  
Randomized Controlled

BackgroundHarmful alcohol use leads to a large burden of disease and disability which disportionately impacts LMICs. The World Health Organization and the Lancet have issued calls for this burden to be addressed, but issues remain, primarily due to gaps in information. While a variety of interventions have been shown to be effective at reducing alcohol use in HICs, their efficacy in LMICs have yet to be assessed. This systematic review describes the current published literature on alcohol interventions in LMICs and conducts a meta analysis of clinical trials evaluating interventions to reduce alcohol use and harms in LMICs.MethodsIn accordance with PRISMA guidelines we searched the electronic databases Pubmed, EMBASE, Scopus,Web of Science, Cochrane, and Psych Info. Articles were eligible if they evaluated an intervention targeting alcohol-related harm in LMICs. After a reference and citation analysis, we conducted a quality assessment per PRISMA protocol. A meta-analysis was performed on the 39 randomized controlled trials that evaluated an alcohol-related outcome.ResultsOf the 3,801 articles from the literature search, 87 articles from 25 LMICs fit the eligibility and inclusion criteria. Of these studies, 39 randomized controlled trials were included in the meta-analysis. Nine of these studies focused specifically on medication, while the others focused on brief motivational intervention, brain stimulation, AUDIT-based brief interventions, WHO ASSIST-based interventions, group based education, basic screening and interventions, brief psychological or counseling, dyadic relapse prevention, group counseling, CBT, motivational + PTSD based interview, and health promotion/awareness. Conclusion Issues in determining feasible options specific to LMICs arise from unstandardized interventions, unequal geographic distribution of intervention implementation, and uncertain effectiveness over time. Current research shows that brain stimulation, psychotherapy, and brief motivational interviews have the potential to be effective in LMIC settings, but further feasibility testing and efforts to standardize results are necessary to accurately assess their effectiveness.

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