Risk Factors for Renal Scarring and Vesicoureteral Reflux in 421 Children After Their First Acute Pyelonephritis, and Appraisal of International Guidelines

2020 ◽  
Author(s):  
Anders Breinbjerg ◽  
Cecilie Siggaard Jorgensen ◽  
Joergen Froekiaer ◽  
Kjell Tullus ◽  
Konstantinos Kamperis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vesicoureteral Reflux ◽  
Acute Pyelonephritis ◽  
Renal Scarring ◽  
International Guidelines

scholarly journals Study of DMSA (99mTc-dimercaptosuccinic acid) scan disorders in children 1-12 years with first acute pyelonephritis and its association with vesicoureteral reflux

2018 ◽  
Vol 6 (3) ◽  
pp. 751
Author(s):  
Majid Vafaie ◽  
Javad Zare-noghabi ◽  
Hadiseh Bahri
Keyword(s):  
Vesicoureteral Reflux ◽  
Acute Pyelonephritis ◽  
Renal Scarring ◽  
High Sensitivity ◽  
Cross Sectional ◽  
Significant Difference ◽  
Febrile Uti ◽  
Dimercaptosuccinic Acid Scan ◽  
Dmsa Scan ◽  
Negative Urine Culture

Background: Acute pyelonephritis and vesicoureteral reflux are one of the main causes of renal scarring in children, which can lead to serious complications such as hypertension and chronic renal failure. The aim of this study was to evaluate the scan disorders in children aged 1-12 years with acute pyelonephritis and its relation with ureteral bladder reflux.Methods: This retrospective cross-sectional descriptive study was conducted on all patients who had been diagnosed with febrile UTI for 4 years (2012-2015) in Ardebil's Children's Hospital. Information about 99mTc-DMSA scan and ultrasonography and cystoyurethrography of patients were extracted from the files and then analyzed by statistical methods inSPSS.19.Results: 148 children (9 boys and 139 girls) with a range of 1 to 12 years old (mean age of 52.34±4.34 months) were included in the study. Of these, 123 patients were subjected to cystoyurethrography after a negative urine culture. A 99mTc-DMSA scan report in the acute phase of the disease was abnormal in 80.4% of the children. VCUG and RNC tests were performed in 123 patients, in 70 (57%) normal cases, and in 53 cases (43%) of urinary reflux. The incidence of reflux with abnormal 99mTc-DMSA scan was 42%. There was no significant correlation between the prevalence of reflux in patients with abnormal 99mTc-DMSA scan in two groups of 1-4 years old and more than 4 years old. No significant difference was found in patients with abnormal scan in responding to treatment and comparing fever after admission in patients with normal 99mTc-DMSA.Conclusions: The results indicate high prevalence of reflux in patients with acute pyelonephritis. Due to the high sensitivity of the scan to detect pyelonephritis and, Pyelonephritis.

Relationship between acute pyelonephritis, renal scarring, and vesicoureteral reflux

2004 ◽  
Vol 19 (10) ◽  
Author(s):  
Pilar Orellana ◽  
Paulina Baquedano ◽  
Venkatesh Rangarajan ◽  
JinHua Zhao ◽  
NgDavidChee Eng ◽  
...  
Keyword(s):  
Vesicoureteral Reflux ◽  
Acute Pyelonephritis ◽  
Renal Scarring

Predictive Risk Factors in Childhood Urinary Tract Infection, Vesicoureteral Reflux, and Renal Scarring Management

2013 ◽  
Vol 53 (12) ◽  
pp. 1119-1133 ◽  
Author(s):  
Stylianos Roupakias ◽  
Xenophon Sinopidis ◽  
Ageliki Karatza ◽  
Anastasia Varvarigou
Keyword(s):  
Risk Factors ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Vesicoureteral Reflux ◽  
Renal Scarring ◽  
Predictive Risk

scholarly journals Renal Scarring in Children with Primary Vesicoureteral Reflux Disease

2019 ◽  
pp. 1-7
Author(s):  
Khalid Kawoosa ◽  
Rahid Rasool Malla ◽  
Wasim Ahmad Wani ◽  
Mudasir Nazir ◽  
Syed Heena Kubravi
Keyword(s):  
Risk Factors ◽  
Vesicoureteral Reflux ◽  
Prospective Observational Study ◽  
Renal Scarring ◽  
Age Groups ◽  
Significant Risk ◽  
Medical Sciences ◽  
Significant Difference ◽  
End Stage ◽  
Primary Vesicoureteral Reflux

Aims: To determine the incidence of renal scarring among patients with primary vesicoureteral reflux (VUR) and the possible risk factor(s), we studied 69 children (42 girls and 27 boys) with VUR attending the Pediatric opd. Study Design: Prospective Observational study. Place and duration of Study: Department of pediatrics, Sher I Kashmir Institute of Medical Sciences, Srinagar, Kashmir between June 2017 to June 2018. Methodology:  All the patients were assessed for VUR grade by voiding cystoureterography and for presence of renal scarring by (99 m) technetium dimercapto–succinic acid scintigraphy. Results: Grade of reflux and number of urinary tract infection (UTI) episodes (≥3) were found to be statistically significant risk factors for renal scarring (P <0.05). However, there was no significant association with gender, familial history and laterality of the disease (P >0.05). Similarly, there was no statistically significant difference of frequency of renal scarring among the different age groups (P >0.05). Conclusions: It was concluded that recurrences of UTI and VUR severity are significant risk factors for renal scarring in children with VUR. Therefore, identification of VUR at an early age may offer the opportunity to prevent episodes of UTI and possible formation of renal scars that may result in end-stage renal failure.

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