Secretin Receptor-Deficient Mice Exhibit Robust Food Anticipatory Activity

2021 ◽  
Author(s):  
Mizuki Sugiyama ◽  
Ichiko Nishijima ◽  
Wataru Nakamura ◽  
Takahiro J. Nakamura
Keyword(s):  
Secretin Receptor ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
Deficient Mice

scholarly journals Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice

eLife ◽  
2014 ◽  
Vol 3 ◽  
Author(s):  
Christian M Gallardo ◽  
Martin Darvas ◽  
Mia Oviatt ◽  
Chris H Chang ◽  
Mateusz Michalik ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Dorsal Striatum ◽  
D1 Receptor ◽  
Circadian Oscillators ◽  
Food Anticipatory Activity ◽  
Dopamine Signaling ◽  
Anticipatory Activity ◽  
Dopamine Receptor 1 ◽  
Deficient Mice

Daily rhythms of food anticipatory activity (FAA) are regulated independently of the suprachiasmatic nucleus, which mediates entrainment of rhythms to light, but the neural circuits that establish FAA remain elusive. In this study, we show that mice lacking the dopamine D1 receptor (D1R KO mice) manifest greatly reduced FAA, whereas mice lacking the dopamine D2 receptor have normal FAA. To determine where dopamine exerts its effect, we limited expression of dopamine signaling to the dorsal striatum of dopamine-deficient mice; these mice developed FAA. Within the dorsal striatum, the daily rhythm of clock gene period2 expression was markedly suppressed in D1R KO mice. Pharmacological activation of D1R at the same time daily was sufficient to establish anticipatory activity in wild-type mice. These results demonstrate that dopamine signaling to D1R-expressing neurons in the dorsal striatum plays an important role in manifestation of FAA, possibly by synchronizing circadian oscillators that modulate motivational processes and behavioral output.

Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice

2005 ◽  
Vol 52 (2) ◽  
pp. 166-173 ◽  
Author(s):  
Michihiko Iijima ◽  
Shun Yamaguchi ◽  
Gijsbertus T.J. van der Horst ◽  
Xavier Bonnefont ◽  
Hitoshi Okamura ◽  
...  
Keyword(s):  
Activity Rhythm ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
Deficient Mice

scholarly journals Circadian Regulation of Food-Anticipatory Activity in Molecular Clock–Deficient Mice

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e48892 ◽  
Author(s):  
Nana N. Takasu ◽  
Gen Kurosawa ◽  
Isao T. Tokuda ◽  
Atsushi Mochizuki ◽  
Takeshi Todo ◽  
...  
Keyword(s):  
Molecular Clock ◽  
Circadian Regulation ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
Deficient Mice

scholarly journals Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice

2010 ◽  
Vol 298 (2) ◽  
pp. R467-R477 ◽  
Author(s):  
Éva Szentirmai ◽  
Levente Kapás ◽  
Yuxiang Sun ◽  
Roy G. Smith ◽  
James M. Krueger
Keyword(s):  
Locomotor Activity ◽  
Body Temperature ◽  
Restricted Feeding ◽  
Wild Type ◽  
Light Phase ◽  
Temperature Changes ◽  
Daily Amount ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
Deficient Mice

Behavioral and physiological rhythms can be entrained by daily restricted feeding (RF), indicating the existence of a food-entrainable oscillator (FEO). One manifestation of the presence of FEO is anticipatory activity to regularly scheduled feeding. In the present study, we tested if intact ghrelin signaling is required for FEO function by studying food anticipatory activity (FAA) in preproghrelin knockout (KO) and wild-type (WT) mice. Sleep-wake activity, locomotor activity, body temperature, food intake, and body weight were measured for 12 days in mice on a RF paradigm with food available only for 4 h daily during the light phase. On RF days 1–3, increases in arousal occurred. This response was significantly attenuated in preproghrelin KO mice. There were progressive changes in sleep architecture and body temperature during the subsequent nine RF days. Sleep increased at night and decreased during the light periods while the total daily amount of sleep remained at baseline levels in both KO and WT mice. Body temperature fell during the dark but was elevated during and after feeding in the light. In the premeal hours, anticipatory increases in body temperature, locomotor activity, and wakefulness were present from RF day 6 in both groups. Results indicate that the preproghrelin gene is not required for the manifestation of FAA but suggest a role for ghrelinergic mechanisms in food deprivation-induced arousal in mice.

scholarly journals Robust Food Anticipatory Activity in BMAL1-Deficient Mice

PLoS ONE ◽  
2009 ◽  
Vol 4 (3) ◽  
pp. e4860 ◽  
Author(s):  
Julie S. Pendergast ◽  
Wataru Nakamura ◽  
Rio C. Friday ◽  
Fumiyuki Hatanaka ◽  
Toru Takumi ◽  
...  
Keyword(s):  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
Deficient Mice

scholarly journals Altered Circadian Food Anticipatory Activity Rhythms in PACAP Receptor 1 (PAC1) Deficient Mice

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0146981 ◽  
Author(s):  
Jens Hannibal ◽  
Birgitte Georg ◽  
Jan Fahrenkrug
Keyword(s):  
Activity Rhythms ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
Deficient Mice

scholarly journals Sex differences in circadian food anticipatory activity are not altered by individual manipulations of sex hormones or sex chromosome copy number in mice

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0191373 ◽  
Author(s):  
Antonio Aguayo ◽  
Camille S. Martin ◽  
Timothy F. Huddy ◽  
Maya Ogawa-Okada ◽  
Jamie L. Adkins ◽  
...  
Keyword(s):  
Sex Differences ◽  
Sex Hormones ◽  
Copy Number ◽  
Sex Chromosome ◽  
Chromosome Copy Number ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity

Food anticipatory activity and photic entrainment in food-restricted BALB/c mice

2000 ◽  
Vol 68 (5) ◽  
pp. 655-666 ◽  
Author(s):  
M.M Holmes ◽  
R.E Mistlberger
Keyword(s):  
Photic Entrainment ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity
Sign in / Sign up

Export Citation Format

Share Document