Pre-hospital statin therapy may not reduce incidence of all-cause mortality and overall MACCE during hospital stay after coronary artery bypass graft surgery

2009 ◽  
Vol 64 (2) ◽  
pp. 253-257 ◽  
Author(s):  
J-P. Kang M. Zhang
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Hospital Stay ◽  
Statin Therapy ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft ◽  
All Cause Mortality

A Comparative Study of Preemptive Effect of Pregabalin and Gabapentin on Postoperative Pain After Coronary Artery Bypass Graft Surgery

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohamed Saeed Abdelaziz ◽  
Randa Ali Shoukry Mohamed ◽  
Mohamed Abdelmohsen Abdelnaeim Ismail ◽  
Ahmed Nabil Ahmed Talaat Mohamed
Keyword(s):  
Patient Satisfaction ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Hospital Stay ◽  
Coronary Artery Bypass ◽  
Pain Control ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Morphine Consumption ◽  
Artery Bypass Graft

Abstract Background Pain that pursues coronary artery bypass graft (CABG) surgery is usually associated with increased both recovery duration and hospital stay. Patient outcome could be worsened owing to large doses of opioids for pain control through over sedation, and prolonged mechanical ventilation. This study was designed to evaluate the effect of preemptive gabapentinoids on post CABG surgery pain control. Objective to evaluate the effect of pre-operative administration of pregabalin and gabapentin in limiting the post-operative pain in coronary artery bypass surgeries. Patients and Methods Type of Study: Prospective double – blinded, randomized controlled Trial. After Approval is obtained from the research ethics committee of anesthesia and intensive care department, Ain Shams University. Study Setting: National Heart Institute, Egypt. Study Period: 6 months. Study Population: adult undergoing coronary artery bypass graft surgeries. Results The primary outcome of this study was to compare the effect of gabapentinoids on post CABG pain as reflected by morphine consumption. The secondary outcome was to address the influence of gabapentinoids on patient satisfaction post CABG, the incidence of respiratory depression, nausea, vomiting, ventilatory hours and length of hospital stay. Conclusion Pregabalin, and gabapentin both can be effective for reduction of post CABG morphine consumption and have better patient satisfaction if given preemptively with single dose preoperatively.

scholarly journals VALIDATION OF MAXIMUM OXYGEN CONSUMPTION (VO2 MAX) WITH SOCIETY OF THORACIC SURGEON (STS) RISK SCORE IN PREOPERATIVE ASSESSMENT OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT (CABG) SURGERY: A PILOT STUDY

2021 ◽  
Vol 70 (Suppl-4) ◽  
pp. S897-903
Author(s):  
Imtiaz Ahmad Chaudhry ◽  
Farrah Pervaiz ◽  
Kaleem Ahmed ◽  
Mehwish Naseer ◽  
Aysha Siddiqa ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Hospital Stay ◽  
Coronary Artery Bypass ◽  
Scoring System ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Preoperative Assessment ◽  
Artery Bypass Graft ◽  
Vo2 Max

Objective: To validate VO2 max testing with society of thoracic surgeon (STS) score in the preoperative assessment of patients undergoing coronary artery bypass graft surgery. Study Design: This was a single center and observational study. Place and Duration of Study: Armed Forces Institute of Cardiology and National Institute of Heart Diseases, Rawalpindi Methodology: Forty four adult patients undergoing elective on pump coronary artery bypass graft surgery with an EF of >45% were included in this study as per inclusion criteria through non probability consecutive sampling. Five patients were lost to follow up. In 39 patients preoperative society of thoracic surgeons scoring was done and VO2 max of these patients was calculated. After coronary artery bypass graft surgery these patients were followed for mortality and morbidity. The discriminative capacity of VO2 max was compared with the STS risk scoring system using Receiver Operating Characteristic curves (ROC-curves). Results: We analyzed the data of 39 patients male 35 (89.7%), female 4 (10.3%). Mean age of our study population was 55.0 ± 10.2 years and a mean BMI of 26.8 ± 3.81. There were 20 (54.1%) hypertensives, 2 (5.4%) diabetics and 5 (13.5%) smokers. There was only one patient with a history of previous myocardial infarction. Majority of the patients belonged to NYHA class II 30 (76.9%) with a mean EF of 56.6 ± 5.17. Prolonged Ventilation (>24 hrs) was significantly associated with lesser values of VO2 max with a p-value of 0.01. Similarly, post-operative mortality and prolonged hospital stay in the low VO2 max groups correlated with the trends predicted by the society of thoracic surgeons scoring system. Conclusion: We conclude from this study that low preoperative VO2 max levels correlated well with STS scoring system for predicting mortality, ventilation time and length of hospital stay.

scholarly journals 462 Factors Associated with Longer Post-Operative Hospital Stay Following First Time Coronary-Artery-Bypass-Graft (CABG)

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
L Ishak ◽  
K Morcos ◽  
P Curry
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Hospital Stay ◽  
Renal Dysfunction ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Left Ventricular ◽  
Artery Bypass Graft ◽  
First Time

Abstract Prolonged post-operative hospital stay is associated with worse patient healthcare outcomes. Aim To identify parameters which correlate with longer post-operative hospital stay (POHS) following first time Coronary-Artery-Bypass-Graft (CABG) Method Data was collected retrospectively on 50 patients who underwent a first time CABG between 12/02/2020 – 21/09/2020 at the Golden Jubilee National Hospital (GJNH). Data included patient demographics, body-mass-index (BMI), presence of co-morbidities, peri-operative blood results, pre-operative renal dysfunction, left ventricular systolic dysfunction (LVSD), severity of left main stem disease, New York Heart Association (NYHA) Functional Classification score, number of grafts, cross-clamp time and bypass time. Results The mean POHS was 7.5 days. Patients with a POHS>7.5 days had a total mean POHS twice as long (12.07 vs 5.7 days, p < 0.001). They spent more time in intensive care unit (2.6 vs 0.97 days, P = 0.05), high dependency unit (2.5 vs 1.2 days, p = 0.005) and ward (7 vs 3.5 days, p = 0.001) compared to the shorter POHS group. They had a higher mean age (69 vs 65, p = 0.036), lower mean CrCl (80.32 vs 95.14, p = 0.141), higher mean renal dysfunction severity grades (0.8 vs 0.28, p = 0.014), higher mean LVSD severity grades (0.33 vs 0.17, p = 0.35) and higher mean NYHA scores (2.2 vs 1.88, p = 0.17). More of the patients had renal dysfunction (p = 0.01), were on ≥ 2 anticoagulants (p = 0.028), had sub-optimal pre-operative bloods (p = 0.075) and required blood transfusion post-operatively (p = 0.02). One patient in the longer POHS group died. Conclusions Longer POHS was associated with older age, worse renal function, presence of co-morbidities, sub-optimal peri-operative blood levels and requirement for post-operative blood transfusions.

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