scholarly journals Celecoxib in breast cancer prevention and therapy

2018 ◽  
Vol Volume 10 ◽  
pp. 4653-4667 ◽  
Author(s):  
Jieqing Li ◽  
Qiongyu Hao ◽  
Wei Cao ◽  
Jaydutt V Vadgama ◽  
Yong Wu
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Prevention And Therapy

Breast cancer and sphingolipid signalling

2005 ◽  
Vol 72 (S1) ◽  
pp. 5-13 ◽  
Author(s):  
Paola Signorelli ◽  
Riccardo Ghidoni
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Biological Membranes ◽  
Breast Cancer Prevention ◽  
Intracellular Signalling ◽  
Regulated Functions ◽  
Tumour Initiation ◽  
Prevention And Therapy

Cancer develops from overlapping events that tend to deregulate the metabolism and unbalance the homeostasis of cells. Sphingolipids, major components of biological membranes, are also mediators of intracellular signalling. Their metabolism can be influenced by diverse stimuli and the accumulation or deficiency of intermediates may trigger proliferation and/or impair the ability of damaged cells to undergo apoptosis. Many sphingolipid-regulated functions are implicated in tumour initiation, promotion, progression and responsiveness to chemotherapy. In this review, evidence of the alteration of sphingolipids metabolism and signalling will be discussed in breast cancer prevention and therapy.

Mammary stem cells: the root of breast cancer?

2004 ◽  
Vol 7 (9) ◽  
Author(s):  
H. A. Coppock ◽  
R. B. Clarke
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Mammary Gland ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Differentiated Cells ◽  
Mammary Stem ◽  
Tissue Specific Stem Cells ◽  
Prevention And Therapy

Tissue-specific stem cells play a key role in organ homoeostasis. They are relatively well characterized in systems which undergo constant proliferation and production of differentiated cells, including the haemopoietic system, skin and intestine. However, little is known about the role and regulation of stem cells in the mammary gland. This review briefly summarizes the current understanding of the role of breast-specific stem cells in normal and cancerous tissues, and how this may identify new targets for breast cancer prevention and therapy.

Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms

2016 ◽  
Vol 40-41 ◽  
pp. 209-232 ◽  
Author(s):  
Dona Sinha ◽  
Nivedita Sarkar ◽  
Jaydip Biswas ◽  
Anupam Bishayee
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Molecular Mechanisms ◽  
Breast Cancer Prevention ◽  
Prevention And Therapy

Simultaneous downregulation of miR-21 and miR-155 through oleuropein for breast cancer prevention and therapy

2018 ◽  
Vol 119 (9) ◽  
pp. 7151-7165 ◽  
Author(s):  
Maryam Abtin ◽  
Mohammad R. Alivand ◽  
Mahmoud S. Khaniani ◽  
Milad Bastami ◽  
Mohammad Zaeifizadeh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Prevention And Therapy

Abstract CN13-03: Intraductal route of breast cancer prevention and therapy: from preclinical studies to Phase I trials

2008 ◽  
Author(s):  
Saraswati Sukumar ◽  
Vered Stearns ◽  
Nagi Khouri ◽  
Lisa Jacobs ◽  
Stacie Jeter ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Phase I ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Preclinical Studies ◽  
Phase I Trials ◽  
Prevention And Therapy

BRCA1 as Target for Breast Cancer Prevention and Therapy

2014 ◽  
Vol 15 (1) ◽  
pp. 4-14 ◽  
Author(s):  
Alberto Romagnolo ◽  
Donato Romagnolo ◽  
Ornella Selmin
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Prevention And Therapy
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