scholarly journals Anti-MUC1 nano-aptamers for triple-negative breast cancer imaging by single-photon emission computed tomography in inducted animals: initial considerations

2016 ◽  
Vol Volume 12 ◽  
pp. 53-60 ◽  
Author(s):  
Fagner Santos do Carmo ◽  
Eduardo Ricci-Junior ◽  
Cristal Cerqueira-Coutinho ◽  
Marta de Souza Albernaz ◽  
Emerson Soares Bernardes ◽  
...  
2019 ◽  
Vol 9 (2) ◽  
pp. 20-26
Author(s):  
A. G. Kislichko ◽  
M. S. Ramazanova

Objective. To evaluate the efficacy of single-photon emission computed tomography combined with computed tomography (SPECT-CT) in the diagnosis of breast cancer (BC).Materials and methods. We performed 44 SPECT-CT examinations in 40 women with malignant breast neoplasms.Study Results. The obtained data enabled us to calculate the characteristics of SPECT-CT in the evaluation of the primary tumor. The sensitivity, specificity, and diagnostic accuracy of the method were 88.1 %, 78.3 %, and 88.0 %, respectively. When the method was used to detect nodal and distant metastases, these characteristics were 87.3 %, 76.8 %, 86.9 % and 82.6 %, 73.1 %, 81.4 %, respectively.Conclusion. SPECT-CT is one of the most accurate methods to assess the primary tumor, lymph node involvement and distant metastases in BC. 


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