scholarly journals Development of an Experimental Dentifrice with Hydroxyapatite Nanoparticles and High Fluoride Concentration to Manage Root Dentin Demineralization

2020 ◽  
Vol Volume 15 ◽  
pp. 7469-7479
Author(s):  
Aila Maria Cipriano Leal ◽  
Marcus Vinícius Beserra dos Santos ◽  
Edson Cavalcanti da Silva Filho ◽  
André Luis Menezes Carvalho ◽  
Cinthia Pereira Machado Tabchoury ◽  
...  
2021 ◽  
Vol 18 (1) ◽  
pp. 107-112
Author(s):  
Thirumala Mothe ◽  
Patnam Umashankar ◽  
Vishnuvardhan Reddy Sultanpuram

Consuming of water contaminated with high fluoride concentration for a very long time causes health problems such as, dental and skeletal fluorosis. Hence, defluoridation of water is essentially required before consumption, when water is contaminated with high fluoride concentration. In this present study, research was focussed on to isolate bacteria which are showing fluoride resistantance from samples of ground water from high fluoride affected regions of Nalgonda. After analysis of 10 samples from different areas of Nalgonda district, two samples of ground water from Narketpally and Nampally showed the high fluoride concentrations of 9.18 ppm and 7.55 ppm respectively. Hence, in the present study, Narketpally ground water sample with highest ppm was considered to isolate fluoride resistant bacteria. A total of eight fluoride resistant organisms were purified from this sample with varying fluoride resistance on Luria Bertani agar with varying fluoride concentraion from 25mg/L to 600mg/L at pH 7. Among the eight strains isolated, three strains MB1, F and G were showing high fluoride resistance (up to 500mg/L), which were further explored for their role in bioremediation of fluoride. In batch mode study, MB1 strain showed high fluoride degradation of 68%, whereas, F and G strains showed 57% and 44%fluoride removal, respectively, when fluoride concentration was present at 20 mgL-1 at 30 °C temperature and pH 7, with dextrose (10 g) utilised as source of carbon per 100 mL media after incubation of 8 days. Results indicate that, MB1 possibly a potential fluoride resistant bacterium with high fluoride bioremediation capacity.


1989 ◽  
Vol 3 (2) ◽  
pp. 203-210 ◽  
Author(s):  
T. Yanagisawa ◽  
S. Takuma ◽  
O. Fejerskov

Materials used in this work were 13 permanent molars exhibiting dental fluorosis (between 5 and 9 on the Thylstrup-Fejerskov scale, 1978) obtained from adults (aged 20-40 years) living in regions with 3.5 ppm fluoride in the water supplies. Small but deep occlusal caries lesions necessitated extraction. Light and polarized microscopic, microradiographic, electron microscopic, and electron-probe- and ion-micro-analytical studies were made. Enamel surfaces were generally cloudy to opaque, with several pits or defects of various sizes and degrees of brown-staining. An extensively hypomineralized area extended from the inner enamel to the surface layer, which was mineralized to a high degree. The hypomineralized area contained sparsely arranged, flattened, hexagonal crystals with either perforated centers or defects extending from the perimeter and indicating either no or low fluoride content. The highly mineralized surface layer, however, was composed of many large, flattened, hexagonal crystals and extremely small, irregularly shaped crystals. Both types were free of central perforations and defects. A high fluoride concentration was determined in the highly mineralized surface layer. These findings suggest that the hypomineralized area undergoes caries-like changes in terms of crystal dissolution and that the highly mineralized surface layer contains hydroxyapatite and fluoridated-hydroxyapatite, or fluorapatite, or both.


2006 ◽  
Vol 40 (2) ◽  
pp. 148-153 ◽  
Author(s):  
M.D. Lagerweij ◽  
W. Buchalla ◽  
S. Kohnke ◽  
K. Becker ◽  
Á.M. Lennon ◽  
...  

2016 ◽  
Vol 50 (Suppl. 1) ◽  
pp. 50-60 ◽  
Author(s):  
Gail V.A. Douglas ◽  
Martin P. Ramsdale ◽  
Karen Vinall-Collier ◽  
Julia I. Csikar

Despite improvements in dental caries levels since the widespread introduction of fluoride toothpastes, it is still a disease which is considered to be a priority in many countries around the world. Individuals at higher risk of caries can be targeted with products with a high fluoride concentration to help reduce the amount and severity of the disease. This paper compares guidance from around the world on the use of products with a high fluoride concentration and gives examples of how guidance has been translated into activity in primary care dental practice. A rapid review of electronic databases was conducted to identify the volume and variation of guidance from national or professional bodies on the use of products with a high fluoride concentration. Fifteen guidelines published within the past 10 years and in English were identified and compared. The majority of these guidelines included recommendations for fluoride varnish use as well as for fluoride gels, while a smaller number offered guidance on high fluoride strength toothpaste and other vehicles. Whilst there was good consistency in recommendations for fluoride varnish in particular, there was sometimes a lack of detail in other areas of recommendation for other vehicles with a high fluoride concentration. There are good examples within the UK, such as the Childsmile project and Delivering Better Oral Health, which highlight that the provision of evidence-based guidance can be influential in directing scarce resources towards oral health improvements. Policy can be influenced by evidence-based national recommendations and used to help encourage dental professionals and commissioners and third-party payers to adopt higher levels of practices aimed at oral health improvement.


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