Immune Checkpoint Inhibitor Therapy Achieved Complete Response for Drug-Sensitive EGFR/ALK Mutation-Negative Metastatic Pulmonary Large-Cell Neuroendocrine Carcinoma with High Tumor Mutation Burden: A Case Report

Author(s):

Xin Zhang ◽

Yanbin Sun ◽

Yuan Miao ◽

Shun Xu

Keyword(s):

Case Report ◽

Neuroendocrine Carcinoma ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Large Cell ◽

Complete Response ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Association of the adoption of immune checkpoint inhibitor therapy (ICT) with prevalence of tumor mutation burden (TMB) in sixteen cancer types.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.e18557 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. e18557-e18557

Author(s):

Leigh Baumgart ◽

Sandeep K. Reddy ◽

Chad Garner ◽

J Zachary Sanborn ◽

William A. Flood

Keyword(s):

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Inhibitor Therapy ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Checkpoint Inhibitor Therapy ◽

Cancer Types

Abstract P4-04-11: A small amount of primary breast cancer shows high tumor mutation burden that may benefit from immune checkpoint inhibitor therapy

10.1158/1538-7445.sabcs18-p4-04-11 ◽

2019 ◽

Author(s):

J Wang ◽

W Chen ◽

Z Jiang ◽

X Lin ◽

T Qin ◽

...

Keyword(s):

Breast Cancer ◽

Immune Checkpoint ◽

Primary Breast Cancer ◽

Checkpoint Inhibitor ◽

Inhibitor Therapy ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Higher Tumor Mutation Burden and Higher PD-L1 Activity Predicts the Efficacy of Immune Checkpoint Inhibitor Treatment in a Patient With Four Lung Cancers. A Case Report

Frontiers in Oncology ◽

10.3389/fonc.2020.00689 ◽

2020 ◽

Vol 10 ◽

Author(s):

Katsuo Usuda ◽

Yo Niida ◽

Shun Iwai ◽

Aika Funasaki ◽

Atsushi Sekimura ◽

...

Keyword(s):

Case Report ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Tumor Mutation Burden ◽

Lung Cancers ◽

Mutation Burden ◽

Inhibitor Treatment

Metachronous Esophageal Ulcers after Immune-mediated Colitis Due to Immune Checkpoint Inhibitor Therapy: A Case Report and Literature Review

Internal Medicine ◽

10.2169/internalmedicine.6606-20 ◽

2021 ◽

Author(s):

Soichiro Ogawa ◽

Hiroshi Kawakami ◽

Sho Suzuki ◽

Daisuke Kuroki ◽

Naomi Uchiyama ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Inhibitor Therapy ◽

Immune Mediated ◽

Checkpoint Inhibitor Therapy ◽

Esophageal Ulcers

A robust response to combination immune checkpoint inhibitor therapy in HPV-related small cell cancer: a case report

Journal for ImmunoTherapy of Cancer ◽

10.1186/s40425-018-0348-4 ◽

2018 ◽

Vol 6 (1) ◽

Cited By ~ 9

Author(s):

Won Jin Ho ◽

Lisa Rooper ◽

Sarah Sagorsky ◽

Hyunseok Kang

Keyword(s):

Case Report ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Cell Cancer ◽

Small Cell ◽

Inhibitor Therapy ◽

Small Cell Cancer ◽

Checkpoint Inhibitor Therapy ◽

Robust Response

Lung adenocarcinoma with tumor resolution and dystrophic calcification after salvage surgery following immune checkpoint inhibitor therapy: A case report

Thoracic Cancer ◽

10.1111/1759-7714.13663 ◽

2020 ◽

Vol 11 (11) ◽

pp. 3396-3400 ◽

Author(s):

Toshiyuki Sumi ◽

Hirofumi Uehara ◽

Toshiaki Masaoka ◽

Makoto Tada ◽

Yoshiko Keira ◽

...

Keyword(s):

Case Report ◽

Lung Adenocarcinoma ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Salvage Surgery ◽

Inhibitor Therapy ◽

Dystrophic Calcification ◽

New DKA in a geriatric patient on immune checkpoint inhibitor therapy: a case report

CJEM ◽

10.1007/s43678-021-00145-4 ◽

2021 ◽

Author(s):

Anton Nikouline ◽

Mike Brzozowski

Keyword(s):

Case Report ◽

Immune Checkpoint ◽

Geriatric Patient ◽

Checkpoint Inhibitor ◽

Inhibitor Therapy ◽

Abstract 5528: Evaluation of tumor mutation burden as a biomarker for immune checkpoint inhibitor efficacy: A calibration study of whole exome sequencing with FoundationOne®

10.1158/1538-7445.am2018-5528 ◽

2018 ◽

Cited By ~ 5

Author(s):

Joseph D. Szustakowski ◽

George Green ◽

William J. Geese ◽

Kim Zerba ◽

Han Chang

Keyword(s):

Exome Sequencing ◽

Whole Exome Sequencing ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Tumor Mutation Burden ◽

Whole Exome ◽

Mutation Burden ◽

Calibration Study

DNA Repair Gene Mutations as Predictors of Immune Checkpoint Inhibitor Response beyond Tumor Mutation Burden

Cell Reports Medicine ◽

10.1016/j.xcrm.2020.100034 ◽

2020 ◽

Vol 1 (3) ◽

pp. 100034 ◽

Author(s):

David Hsiehchen ◽

Antony Hsieh ◽

Robert M. Samstein ◽

Tianshi Lu ◽

Muhammad S. Beg ◽

...

Keyword(s):

Dna Repair ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Gene Mutations ◽

Repair Gene ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Dna Repair Gene

Myocarditis associated with immune checkpoint inhibitor therapy: a case report of three patients

Emergency Radiology ◽

10.1007/s10140-020-01765-6 ◽

2020 ◽

Vol 27 (4) ◽

pp. 455-460

Author(s):

Kianoush Ansari-Gilani ◽

Sree Harsha Tirumani ◽

Daniel A. Smith ◽

Ariel Nelson ◽

Asrar Alahmadi ◽

...

Keyword(s):

Case Report ◽

Immune Checkpoint ◽

Checkpoint Inhibitor ◽

Inhibitor Therapy ◽