scholarly journals Drug therapy in the treatment of endometriosis

2016 ◽  
pp. 86-91
Author(s):  
A. A. Popov ◽  
B. A. Slobodyanyuk ◽  
T. N. Manannikova ◽  
A. A. Fedorov ◽  
T. Z. Chanturia ◽  
...  
Keyword(s):  
Chronic Disease ◽  
Drug Therapy ◽  
Surgical Procedures ◽  
Reproductive Medicine ◽  
Management Plan ◽  
Surgical Methods ◽  
American Society ◽  
Practice Committee ◽  
Xix Century ◽  
Methods Of Treatment

Clinical studies of medicine-based and surgical methods for the treatment of endometriosis are described. Although endometriosis was described as early as in the XIX century, the causes for its emergence and spread have not been fully investigated. Also, many questions regarding methods of treatment remain far from being solved. Due to the chronic and often relapsing nature of the disease, Practice Committee of the American Society for Reproductive Medicine (ASRM) has concluded the following: "endometriosis should be viewed as a chronic disease that requires a lifelong management plan with the goal of maximizing the use of medical treatment and avoiding repeated surgical procedures." Thus, treatment of endometriosis should not only be comprehensive but also adapted to the specifics of each woman's organism.

scholarly journals Features of the course of pregnancy in women with polycystic ovary syndrome

2020 ◽  
Vol 69 (5) ◽  
pp. 105-112
Author(s):  
Igor P. Nikolayenkov ◽  
Tatyana U. Kuzminykh ◽  
Marina A. Tarasova ◽  
Darya S. Seryogina
Keyword(s):  
Diabetes Mellitus ◽  
Polycystic Ovary Syndrome ◽  
Reproductive Medicine ◽  
Metabolic Disorders ◽  
Polycystic Ovary ◽  
Cervical Insufficiency ◽  
Ovary Syndrome ◽  
Early Gestation ◽  
Surgical Methods ◽  
Methods Of Treatment

Polycystic ovary syndrome is one of the most common pathologies in the practice of an obstetrician-gynecologist. Overcoming infertility characteristic of this syndrome is an important problem of endocrinology, gynecology, and reproductive medicine. Innovative therapeutic and surgical methods of treatment can correct hormonal and metabolic disorders, induce ovulation and achieve a long-awaited pregnancy. Early gestation periods in patients with polycystic ovary syndrome often occur with miscarriage, and the risks of developing gestational diabetes mellitus, cervical insufficiency, gestational arterial hypertension, preeclampsia, and placental insufficiency increase. We have analyzed modern ideas about the effect of various pathogenetic links of polycystic ovary syndrome on the course of pregnancy.

Modern molecular and biological aspects of endometriosis-associated infertility

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (5) ◽  
pp. 12-15
Author(s):  
Anastasiia S Safronova ◽  
Mikhail Yu Vysokikh ◽  
Vladimir D Chuprynin ◽  
Natalia A Buralkina
Keyword(s):  
Signaling Pathways ◽  
Recurrence Rate ◽  
High Recurrence Rate ◽  
Modern Drug ◽  
Surgical Methods ◽  
Prevention And Treatment ◽  
Biological Aspects ◽  
Methods Of Treatment ◽  
New Strategies

There is currently no consensus on the etiopathogenetic nature of endometriosis. The causes of aggressive, progressive, infiltrative growth of endometrioid tissue also remain unclear. An important problem remains the high recurrence rate of endometriosis, despite the availability of modern drug and surgical methods of treatment. The study of the central signaling pathways and the search for new key molecules is of paramount importance for a better understanding of the pathogenesis of the disease, and is also an important step in the development of new strategies for the diagnosis, prevention and treatment of endometriosis.

METASTATIC LESION OF THE SPINE: DIAGNOSIS AND TACTICS OF SURGICAL TREATMENT

2019 ◽  
Vol 65 (6) ◽  
pp. 868-876
Author(s):  
Anton Yarikov ◽  
Anton Yermolaev ◽  
Igor Smirnov ◽  
Anton Denisov ◽  
Olga Perlmutter ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Epidemiological Studies ◽  
Metastatic Lesion ◽  
Spinal Cord Damage ◽  
Metastatic Lesions ◽  
Spinal Lesions ◽  
Cancer Pathology ◽  
Surgical Methods ◽  
The Stability ◽  
Methods Of Treatment

Epidemiological studies show an increase in the number of people with cancer. Bone metastases are a frequent manifestation of generalized cancer, because it is in malignant tumors of the spine more often than other bones of the skeleton becomes a target for metastasis. The article describes in detail the methods of diagnosis of spinal lesions in cancer pathology. Particular attention is paid to the scales reflecting the severity of the patient’s condition, the degree of spinal cord damage, the severity of pain in metastasis to the spine, the prognosis of survival in oncovertebrology and evaluation of the stability of the spine in metastatic lesions. Further, the paper presents non-radical (decompression, vertebroplasty) and radical (spondylectomy, corporectomy) surgical methods of treatment

scholarly journals Salpingo-oophorectomy versus cystectomy in patients with borderline ovarian tumors: a systemic review and meta-analysis on postoperative recurrence and fertility

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Peng Wang ◽  
Lei Fang
Keyword(s):  
Surgical Procedures ◽  
Postoperative Recurrence ◽  
Pregnancy Rates ◽  
Ovarian Tumors ◽  
Systemic Review ◽  
Cochrane Library ◽  
Risk Of Recurrence ◽  
Borderline Ovarian Tumors ◽  
Surgical Methods ◽  
Meta Analyses

Abstract Background To compare the postoperative recurrence and fertility in patients with borderline ovarian tumors (BOTs) who underwent different surgical procedures: salpingo-oophorectomy versus cystectomy. Methods Potentially relevant literature from inception to Nov. 06, 2020, were retrieved in databases including Cochrane Library, EMBASE (Ovid), and MEDLINE (Pubmed). We applied the keywords “fertility-sparing surgery,” or “conservative surgery,” or “cystectomy,” or “salpingo-oophorectomy,” or “oophorectomy,” or “adnexectomy,” or “borderline ovarian tumor” for literate searching. Systemic reviews and meta-analyses were performed on the postoperative recurrence rates and pregnancy rates between patients receiving the two different surgical methods. Begger’s methods, Egger’s methods, and funnel plot were used to evaluate the publication bias. Result Among the sixteen eligible studies, the risk of recurrence was evaluated in all studies, and eight studies assessed the postoperative pregnancy rates in the BOT patients. A total of 1839 cases with borderline ovarian tumors were included, in which 697 patients (37.9%) received unilateral salpingo-oophorectomy and 1142 patients (62.1%) underwent unilateral/bilateral cystectomy. Meta-analyses showed that BOT patients with unilateral/bilateral cystectomy had significantly higher recurrence risk (OR=2.02, 95% CI: 1.59-2.57) compared with those receiving unilateral salpingo-oophorectomy. Pooled analysis of four studies further confirmed the higher risk of recurrence in patients with cystectomy (HR=2.00, 95% CI: 1.11-3.58). In addition, no significant difference in postoperative pregnancy rate was found between patients with the two different surgical procedures (OR=0.92, 95% CI: 0.60-1.42). Conclusion Compared with the unilateral/bilateral cystectomy, the unilateral salpingo-oophorectomy significantly reduces the risk of postoperative recurrence in patients with BOT, and it does not reduce the pregnancy of patients after surgery. Trial registration PROSPERO CRD42021238177

Sign in / Sign up

Export Citation Format

Share Document