scholarly journals Osteoprotegerin, Soluble Receptor Activator Nuclear Factor-κB Ligand, Nuclear Factor Kappa B and Intestinal Trefoil Factor 3 are Promising Biomarkers in Diagnosis and Follow- up Inflammatory Bowel Disease Patients

2022 ◽  
Vol 86 (1) ◽  
pp. 413-419
Author(s):  
Ragaa Salama ◽  
Mohammed A Medhat ◽  
Shimaa A Elghazally ◽  
Nesma G Farag ◽  
Aya A El Sanory ◽  
...  
Keyword(s):  
Nuclear Factor Kappa B ◽  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Soluble Receptor ◽  
Trefoil Factor ◽  
Intestinal Trefoil Factor ◽  
Trefoil Factor 3 ◽  
Receptor Activator ◽  
Inflammatory Bowel

Osteoprotegerin (OPG) levels, total soluble receptor activator of nuclear factor-Kappa B ligand (total sRANKL) , and RANKL/OPG ratio in patients with rheumatoid arteritis

2017 ◽  
Vol 2 (1) ◽  
pp. 23-29
Author(s):  
Sousan Kolahi ◽  
Amir Ghorbanihaghjo ◽  
Nadereh Rashtchizadeh ◽  
Alireza Khabbazi ◽  
Mehrzad Hajialilo ◽  
...  
Keyword(s):  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
Soluble Receptor ◽  
Nuclear Factor Kappa ◽  
Receptor Activator

scholarly journals Salivary soluble receptor activator of nuclear factor kappa B ligand/osteoprotegerin ratio in periodontal disease and health

2013 ◽  
Vol 43 (5) ◽  
pp. 227 ◽  
Author(s):  
Zahra Alizadeh Tabari ◽  
Abbas Azadmehr ◽  
Mohammad Amir Alizadeh Tabrizi ◽  
Jalaloddin Hamissi ◽  
Fatemeh Baharak Ghaedi
Keyword(s):  
Periodontal Disease ◽  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
Soluble Receptor ◽  
Nuclear Factor Kappa ◽  
Receptor Activator

scholarly journals Lack of NOD2 attenuates ovariectomy-induced bone loss via inhibition of osteoclasts

2017 ◽  
Vol 235 (2) ◽  
pp. 85-96 ◽  
Author(s):  
Ke Ke ◽  
Ok-Joo Sul ◽  
Soo-Wol Chung ◽  
Jae-Hee Suh ◽  
Hye-Seon Choi
Keyword(s):  
Bone Loss ◽  
Nuclear Factor Kappa B ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Nuclear Factor Κb ◽  
Innate Immune ◽  
Nuclear Factor ◽  
Oxygen Species ◽  
Receptor Activator ◽  
Recognition Receptor ◽  
Oligomerization Domain

Nucleotide-binding oligomerization domain-2 (NOD2) is a pattern recognition receptor of the innate immune system. It interacts with serine–threonine kinases to induce activation of nuclear factor κB (NF-κB), which is important for receptor activator of nuclear factor kappa-B ligand (RANKL) signaling. We tested the idea that NOD2 modulates bone metabolism via an action on osteoclasts (OCs). The absence of NOD2 reduced ovariectomy-induced bone loss in mice, and lowered the area and the activity of OCs, by impairing RANKL signaling. It also reduced the level of reactive oxygen species (ROS), as well as of NF-κB-DNA binding upon RANKL exposure. NOD2 was found to physically interact with nicotinamide adenine dinucleotide phosphate oxidase 1, and this led to increased production of ROS in OCs. Our data suggest that NOD2 contributes to bone loss in estrogen deficiency by elevating ROS levels in OCs.

scholarly journals Therapeutic efficacy of soluble receptor activator of nuclear factor-κB-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma

2008 ◽  
Vol 7 (10) ◽  
pp. 3389-3398 ◽  
Author(s):  
François Lamoureux ◽  
Gaëlle Picarda ◽  
Julie Rousseau ◽  
Clothilde Gourden ◽  
Séverine Battaglia ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Mouse Model ◽  
Therapeutic Efficacy ◽  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Soluble Receptor ◽  
Nonviral Gene Transfer ◽  
Receptor Activator

scholarly journals Cathepsin G Enhances Mammary Tumor–Induced Osteolysis by Generating Soluble Receptor Activator of Nuclear Factor-κB Ligand

2008 ◽  
Vol 68 (14) ◽  
pp. 5803-5811 ◽  
Author(s):  
Thomas J. Wilson ◽  
Kalyan C. Nannuru ◽  
Mitsuru Futakuchi ◽  
Anguraj Sadanandam ◽  
Rakesh K. Singh
Keyword(s):  
Mammary Tumor ◽  
Nuclear Factor Κb ◽  
Cathepsin G ◽  
Nuclear Factor ◽  
Soluble Receptor ◽  
Receptor Activator

Soluble Receptor Activator of Nuclear Factor-κB Ligand (sRANKL)/Osteoprotegerin Balance in Ageing and Age-Associated Diseases

2004 ◽  
Vol 5 (2) ◽  
pp. 119-127 ◽  
Author(s):  
Lia Pulsatelli ◽  
Paolo Dolzani ◽  
Tania Silvestri ◽  
Paolo Caraceni ◽  
Andrea Facchini ◽  
...  
Keyword(s):  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Soluble Receptor ◽  
Associated Diseases ◽  
Receptor Activator
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