scholarly journals أسالیب مقدمی الرعایة کمنبئات ببعض المشکلات السلوکیة لدى الأطفال الیتامى ذوی الإعاقة الفکریة البسیطة. Caregivers' Styles as Predictors of some Behavioral Problems among Orphan Children with Mild Intellectual Disability

Author(s):  
محمد عبد الرحمن إبراهیم علی ◽  
عزت عبد الله سلیمان کواسة ◽  
أحمد عبد التواب کامل
2020 ◽  
Vol 5 (12) ◽  

A 14-year-old with mild intellectual disability and autism spectrum disorder was admitted to a long-term psychiatric hospital with complaints of treatment resistant aggressive behavior. Her psychopharmacologic regime was Depakote 1500mg, Intuniv XR 2mg twice daily, and Inderal 10 mg thrice daily, for her mood and behavior symptoms, and prn Ativan and Benadryl for acute episodes of agitation. Despite multiple medication trials, she was continued on Depakote for seven months prior to her admission to long term care. During the first month in long term care, she had over 20 emergency interventions due to physical aggression. She was also witnessed to exhibit abnormal behavior and self-harm during this time. There were concerns that Depakote may be contributing to her dysregulated behavior, thus the medication was slowly down-titrated while her other scheduled medications and dosages remained the same. The patient started to require fewer emergency interventions with noted improvement in her behavior. After the complete termination of Depakote, clinical observations were remarkable for mitigation of aggressive and abnormal behavior as evidenced by the patient going six weeks without any emergency intervention. Behavioral dysregulation is a possible adverse effect of valproate. Individuals with intellectual disabilities are most vulnerable to polypharmacy for management of aggression, behavioral problems, and other psychiatric comorbidities. There is a need for pharmacovigilance on the negative behavioral effects in patients receiving valproate.


2012 ◽  
Vol 11 (1) ◽  
pp. 57-78 ◽  
Author(s):  
Sarah Soenen ◽  
Ina Van Berckelaer-Onnes ◽  
Evert Scholte

This study investigated whether clinical profiles in individuals with mild intellectual disability (MID) could be defined in terms of their histories (e.g., behavioral, social-environmental, educational, and service use characteristics). The clinical psychologists administered the Diagnostic Interview for Social and Communication Disorders to the (substitute) parents and analyzed the clinical records of individuals with MID. Four subtypes of individuals with MID with specific clinical profiles participated in this study. The results of this study, which used discriminant analysis of the individuals’ histories, supported two discriminant functions. The first discriminant function differentiated clinical profiles largely based on developmental disorders from clinical profiles based on personality disorders. The second function differentiated clinical profiles based on personality disorders and externalizing behavioral problems from other clinical profiles. The characteristics in the histories of individuals with MID can be very different and need to be assessed for further understanding of their unique needs.


Author(s):  
K. M. Visser ◽  
L. M. C. Jansen ◽  
A. Popma ◽  
R. R. J. M. Vermeiren ◽  
M. C. Kasius

Abstract Background Levels of aggression are high in residential settings for juveniles with Mild Intellectual Disability (MID). As a result, treatment is less effective, aggression causes injury, traumatic experiences and longer inhabitation for juveniles. Additionally, inpatient aggression has been linked to burnout and stress among group workers, which has negative consequences such as less job satisfaction or poorer work performance Objective Therefore, it is crucial to diminish aggressive incidents in these settings and to find a way for staff how to respond to aggression properly. Methods As there is no intervention method which tackles all of the referred problems efficiently, a new method Non-violent Resistance for MID was introduced into three residential settings for juveniles with MID, in a quasi-experimental stepped wedge design. Reports of aggressive incidents were assessed seven times before, during and after the training in NVR-MID on group level. Multilevel analyses were carried out in order to assess the development of the aggressive incidents over time. Results Aggressive incidents decreased significantly in time during and after training in NVR-MID, this decrease is seen in all three institutions. Thus, regardless of resident’s age, gender or IQ, NVR-MID seemed successful in diminishing aggressive incidents. Furthermore, a significant interaction effect was found between institution and time, indicating that regardless if incidents of aggression were relatively high at baseline, decrease in incidents was similar to institutions where incidents were relatively low on baseline. Conclusions Implementing NVR-MID into residential settings for juveniles with MID and comorbid behavioral problems might help to decrease aggressive incidents.


Author(s):  
Meena Balasubramanian ◽  
Alexander J. M. Dingemans ◽  
Shadi Albaba ◽  
Ruth Richardson ◽  
Thabo M. Yates ◽  
...  

AbstractWitteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental syndrome caused by heterozygous loss-of-function variants in SIN3A. We define the clinical and neurodevelopmental phenotypes related to SIN3A-haploinsufficiency in 28 unreported patients. Patients with SIN3A variants adversely affecting protein function have mild intellectual disability, growth and feeding difficulties. Involvement of a multidisciplinary team including a geneticist, paediatrician and neurologist should be considered in managing these patients. Patients described here were identified through a combination of clinical evaluation and gene matching strategies (GeneMatcher and Decipher). All patients consented to participate in this study. Mean age of this cohort was 8.2 years (17 males, 11 females). Out of 16 patients ≥ 8 years old assessed, eight (50%) had mild intellectual disability (ID), four had moderate ID (22%), and one had severe ID (6%). Four (25%) did not have any cognitive impairment. Other neurological symptoms such as seizures (4/28) and hypotonia (12/28) were common. Behaviour problems were reported in a minority. In patients ≥2 years, three were diagnosed with Autism Spectrum Disorder (ASD) and four with Attention Deficit Hyperactivity Disorder (ADHD). We report 27 novel variants and one previously reported variant. 24 were truncating variants; three were missense variants and one large in-frame gain including exons 10–12.


2013 ◽  
Vol 20 (5) ◽  
pp. 399-407 ◽  
Author(s):  
Vesna Žunić-Pavlović ◽  
Miroslav Pavlović ◽  
Nenad Glumbić

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