scholarly journals Screening for anti HCV

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Fatima Mehboob
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Observational Study ◽  
General Practitioners ◽  
Clinical Features ◽  
Screening Strategy ◽  
Medical Ward ◽  
Hcv Infection ◽  
Hepatitis C Virus Infection

Purpose of this study is to evaluate the different indications for screening for Anti HCV. This study was carried out in outdoor and indoor department of North Medical Ward of Mayo Hospital, Lahore. This is a non-interventional observational study. Two hundred patients ELISA proved HCV infection were evaluated to find out what were the different circumstances or symptomatology when tests for HCV infection were advised. So that a screening strategy can be formed. As hepatitis C virus infection has varied presentation and clinical features, the general practitioners, physicians, dermatologists and psychiatrists should be conscious about it an advise for Anti HCV detection whenever it is suspected. Screening of the early cases is beneficial both for the patients and its relatives.

scholarly journals Occult hepatitis C virus infection in patients with malignant lymphoproliferative disorders

2020 ◽  
Vol 34 ◽  
pp. 205873842096120
Author(s):  
Abeya A Lotfi ◽  
Asmaa E Mohamed ◽  
Nahela A Shalaby ◽  
Deena S Eissa ◽  
Ehab El-Dabaa ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Treatment Protocol ◽  
Lymphoproliferative Disorders ◽  
Hcv Infection ◽  
Hcv Rna ◽  
Hepatitis C Virus Infection ◽  
Occult Hepatitis ◽  
Occult Hepatitis C

Despite the link between HCV and malignant lymphoproliferative disorders has been established, the association between occult hepatitis C virus infection and malignant lymphoproliferative disorders remains obscure. The present study intended to identify the possible association between occult HCV infection and malignant lymphoproliferative disorders. Newly diagnosed patients with LPDs were screened for the presence of HCV-RNA in both plasma and PBMCs. PBMCs of the subjects were also, examined by transmission and immuno-electron microscopy. LPD patients showed a high percentage of HCV infection (71.9%): OCI-HCV (37.5%) and HCV (34.38%). Meanwhile, 28.13% of LPD patients did not show any evidence of HCV infection. Ultrastructural examination of PBMCs revealed the presence of intracytoplasmic vacuoles enclosing viral like particles, which were less prominent in occult HCV patients. The possibility of occult HCV should be considered in patients with LPDs which can be helpful in the management of the treatment protocol in order to set up a balance between the control of the tumor progression and minimizing post chemotherapy complications related to HCV infection.

Clinical features and progression of perinatally acquired hepatitis C virus infection

2003 ◽  
Vol 70 (3) ◽  
pp. 373-377 ◽  
Author(s):  
Massimo Resti ◽  
Paloma Jara ◽  
Loreto Hierro ◽  
Chiara Azzari ◽  
Raffaella Giacchino ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Clinical Features ◽  
Hepatitis C Virus Infection ◽  
Perinatally Acquired

scholarly journals Seroepidemiology of hepatitis C virus infection in Japan and HCV infection in haemodialysis patients

1994 ◽  
Vol 14 (3) ◽  
pp. 253-258 ◽  
Author(s):  
Kazunari Yamaguchi ◽  
Hiroyuki Kiyowa ◽  
Jiroh Machida ◽  
Akira Obayashi ◽  
Noriyuki Nojiri ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hcv Infection ◽  
Hepatitis C Virus Infection

scholarly journals Immunoglobulin GM and KM Allotypes and Prevalence of Anti-LKM1 Autoantibodies in Patients with Hepatitis C Virus Infection

2006 ◽  
Vol 80 (10) ◽  
pp. 5097-5099 ◽  
Author(s):  
Paolo Muratori ◽  
Susan E. Sutherland ◽  
Luigi Muratori ◽  
Alessandro Granito ◽  
Marcello Guidi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Genetic Markers ◽  
Odds Ratio ◽  
Hcv Infection ◽  
Hepatitis C Virus Infection ◽  
Autoimmune Phenomenon ◽  
Microsomal Antigen ◽  
Gm And Km Allotypes

ABSTRACT GM and KM allotypes—genetic markers of immunoglobulin (Ig) γ and κ chains, respectively—are associated with humoral immunity to several infection- and autoimmunity-related epitopes. We hypothesized that GM and KM allotypes contribute to the generation of autoantibodies to liver/kidney microsomal antigen 1 (LKM1) in hepatitis C virus (HCV)-infected persons. To test this hypothesis, we characterized 129 persons with persistent HCV infection for several GM and KM markers and for anti-LKM1 antibodies. The heterozygous GM 1,3,17 23 5,13,21 phenotype was significantly associated with the prevalence of anti-LKM1 antibodies (odds ratio, 5.13; P = 0.002), suggesting its involvement in this autoimmune phenomenon in HCV infection.

Seroprevalence of Hepatitis C Virus Infection and Evaluation of Serum Aminotransferase Levels among Haemodialysis Patients in Izmir, Turkey

2005 ◽  
Vol 33 (6) ◽  
pp. 641-646 ◽  
Author(s):  
AI Olut ◽  
F Ozsakarya ◽  
M Dilek
Keyword(s):  
Enzyme Activity ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hcv Infection ◽  
Important Predictor ◽  
Hcv Rna ◽  
Hepatitis C Virus Infection ◽  
Serum Aminotransferase

The seroprevalence of hepatitis C virus (HCV) infection was investigated among haemodialysis (HD) patients. Mean serum aminotransferase levels were also compared over 3 months in HCV-seropositive patients with and without viraemia, as well as in HCV-seronegative HD patients and HCV-seropositive, non-uraemic, viraemic patients. Seroprevalence of HCV infection was 19% among the 437 HD patients tested. Of the 61 HD HCV-seropositive, hepatotoxic medication- and alcohol-free patients, 38 (62%) were found to be viraemic, using quantitative HCV-RNA, on at least one occasion. Mean serum aminotransferase levels were significantly higher in viraemic HD patients (compared with non-viraemic patients), suggesting that HCV-RNA positivity is an important predictor of increased enzyme activity in these patients. As expected, aminotransferase levels in HCV-seropositive HD patients tended to be lower than levels in HCV-seropositive non-uraemic patients.

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