A novel diabetes mellitus vaccine [Diamyd]* looks promising for long-term preservation of ??-cell function in patients with type 1 diabetes mellitus,

2008 ◽  
Vol &NA; (1622) ◽  
pp. 7
Author(s):  
&NA;
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Cell Function ◽  
Long Term Preservation

scholarly journals Case Report: Markedly Long-Term Preservation of Pancreatic β‐Cell Function in a Subject With Elderly Onset of Type 1 Diabetes Mellitus Showing High-Titer Autoimmune Antibodies for Over 4 Years

2021 ◽  
Vol 12 ◽  
Author(s):  
Ryo Shigemoto ◽  
Takatoshi Anno ◽  
Fumiko Kawasaki ◽  
Kohei Kaku ◽  
Hideaki Kaneto
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Cell Function ◽  
Β Cell ◽  
Cell Destruction ◽  
Β Cell Function ◽  
Long Term Preservation

Type 1 diabetes mellitus (T1DM) is mainly triggered by autoimmune β-cell destruction, usually leading to absolute insulin deficiency. Regarding the speed of β-cell destruction, there are large variations depending on age. In some adult cases, sufficient β-cell function is sometimes retained for a relatively long period and eventually they become dependent on insulin for survival. It is known that even in subjects with T1DM showing high titers of such antibodies, insulin secretory capacity is preserved under several conditions such as “honeymoon” period and slowly progressive T1DM (SPIDDM). Herein, we reported the acute onset T1DM subject with long-term preservation of β-cell function, although his anti-GAD antibody and anti-IA-2 antibody titers were very high for more than 4 years. This case is very important in that his β-cell function was preserved with dipeptidyl peptidase-4 inhibitor alone. This means that there are large variations in the speed of β-cell destruction in the onset of T1DM.

Long-term hyperglycaemia impairs vascular smooth muscle cell function in women with type 1 diabetes mellitus

2009 ◽  
Vol 6 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Niclas Bjarnegård ◽  
Hans J Arnqvist ◽  
Torbjö;rn Lindströ;m ◽  
Lena Jonasson ◽  
Toste Länne
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Type 1 Diabetes Mellitus ◽  
Muscle Cell ◽  
Cell Function

Short and long-term glycemic variability associated with severe hypoglycemia and retinopathy in type 1 diabetes mellitus

2020 ◽  
Author(s):  
Martín Borja Sanz ◽  
Gimeno Sergio Roman ◽  
Peteiro Miranda Carlos Miguel ◽  
Ortez Toro Jose Jorge ◽  
Ana Agudo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Severe Hypoglycemia ◽  
Glycemic Variability ◽  
Short And Long Term

scholarly journals Long-Term Pharmacologic Doses of Vitamin E Only Moderately Affect the Erythrocytes of Patients with Type 1 Diabetes Mellitus

2001 ◽  
Vol 131 (6) ◽  
pp. 1723-1730 ◽  
Author(s):  
Begoña Manuel y Keenoy ◽  
Honglei Shen ◽  
Wendy Engelen ◽  
Jan Vertommen ◽  
Guido Van Dessel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Vitamin E ◽  
Type 1 Diabetes Mellitus

scholarly journals Long-Term Insulin Independence in Type 1 Diabetes Mellitus Using a Simplified Autologous Stem Cell Transplant

2016 ◽  
Vol 101 (5) ◽  
pp. 2141-2148 ◽  
Author(s):  
Olga Graciela Cantú-Rodríguez ◽  
Fernando Lavalle-González ◽  
Miguel Ángel Herrera-Rojas ◽  
José Carlos Jaime-Pérez ◽  
José Ángel Hawing-Zárate ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Stem Cell ◽  
Type 1 Diabetes Mellitus ◽  
Stem Cell Transplant ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Insulin Independence

scholarly journals Retinal vascular fractals predict long-term microvascular complications in type 1 diabetes mellitus: the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987)

Diabetologia ◽  
2014 ◽  
Vol 57 (10) ◽  
pp. 2215-2221 ◽  
Author(s):  
Rebecca Broe ◽  
Malin L. Rasmussen ◽  
Ulrik Frydkjaer-Olsen ◽  
Birthe S. Olsen ◽  
Henrik B. Mortensen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Microvascular Complications ◽  
Pediatric Diabetes ◽  
Danish Cohort
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