scholarly journals BRAYTON-CYCLE RADIOISOTOPE HEAT-SOURCE DESIGN STUDY, PHASE II (PRELIMINARY DESIGN) REPORT.

1967 ◽  
Author(s):  
R Robinson ◽  
T Chapman ◽  
S Ewing ◽  
A Miller ◽  
J Nichols

1967 ◽  
Author(s):  
R.A. Robinson ◽  
R.J. Beaver ◽  
D.W. Burton ◽  
T.G. Chapman ◽  
C.W. Jr. Craven ◽  
...  


1977 ◽  
Author(s):  
Robert L. Berg ◽  
William J. Murphy ◽  
Dennis E. Simmons


2010 ◽  
Author(s):  
Jason A. Dechant ◽  
James S. Thomason ◽  
Ylli Bajraktari ◽  
Mary C. Flythe ◽  
Anthony C. Hermes ◽  
...  
Keyword(s):  
Phase Ii ◽  


1993 ◽  
Author(s):  
Robert W. Marsh ◽  
Mark E. Caron ◽  
Carol Metselaar ◽  
John Steele


1997 ◽  
Vol 3 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Joseph J. Plaud ◽  
Kurt Schweigman ◽  
Thomas K. Welty


1957 ◽  
Author(s):  
L.E. Link ◽  
W.H. Cook ◽  
H. Greenspan ◽  
C.N. Kelber ◽  
J. Ramuta ◽  
...  


1956 ◽  
Author(s):  
M. Treshow ◽  
E. Hamer ◽  
H. Pearlman ◽  
D. Rossin ◽  
D. Shaftman


2003 ◽  
Author(s):  
DR. Stephen Croft ◽  
Mr. David Martancik ◽  
Dr. Brian Young ◽  
Dr. Patrick MJ Chard ◽  
Dr. Robert J Estop ◽  
...  




2020 ◽  
Author(s):  
Timothy M E Davis ◽  
Wendy A Davis

Objective:<b> </b>To determine whether<b> </b>angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) protect against lower respiratory tract infections complicating type 2 diabetes. <p>Research design and methods:<b> </b>Of 1,732 participants with diabetes recruited to the longitudinal observational Fremantle Diabetes Study Phase II (FDS2) between 2008 and 2011, 1,482 had confirmed type 2 diabetes (mean age of 65.8 years, 51.6% were males, median diabetes duration 9.0 years). All were followed for hospitalizations for/with, or deaths from, pneumonia/influenza ascertained from validated administrative data linkage from study entry to end-2016. Cox and competing risk regression were used to identify independent predictors of this outcome.</p> <p>Results:<b> </b>Two-thirds of participants (n=982) were taking an ACEi and/or ARB at study entry (498 (33.6%) ACEi, 408 (27.5%) ARB, 76 (5.1%) both).<b> </b>During 9,511 person-years of follow-up (mean 6.4±2.0 years), 174 participants had incident pneumonia/influenza (156 hospitalizations, 18 deaths without hospitalization). In Cox regression analysis, baseline ACEi/ARB use was independently associated with a reduced risk of incident pneumonia/influenza (cause-specific hazard ratio (HR) (95% confidence interval) 0.64 (0.45, 0.89), <i>P</i>=0.008). Allowing for the competing risk of death did not change this finding (subdistribution HR 0.67 (0.48, 0.95), <i>P</i>=0.024), and similar reductions were seen for ACEi, ARB alone, and ACEi/ARB combination therapy. There was no significant change in use of ACEi/ARB during follow-up (interaction with ln(time), <i>P</i>=0.70). Other significant predictors of incident pneumonia/influenza were previously reported, clinically plausible variables.</p> <p>Conclusions:<b> </b>ACEi/ARB reduce the risk of pneumonia/influenza in community-based people with type 2 diabetes.<b><br> </b></p>



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