Alcoholysis Versus Fission of the Ester Group During the Reaction of Dialkyl Phenylphosphonates in the Presence of Ionic Liquids
In the microwave-assisted alcoholysis of dialkyl phenylphosphonates performed in the presence of suitable ionic liquids, such as [bmim][BF<sub>4</sub>] or [bmim][PF<sub>6</sub>], affording the phosphonate with mixed alkoxy groups and the fully transesterified product, the fission of the phosphonate function to the ester-acid or diacid moiety was inevitable. Moreover, in the presence of [emim][HSO<sub>4</sub>], the reaction could be performed to afford the phosphonic esteracid with a selectivity of 66% and the diacid with a selectivity of 97%. The ester-acids provided by the new protocol may be valuable intermediates.
2016 ◽
Vol 1014
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pp. 45-55
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2006 ◽
Vol 8
(3)
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pp. 460-464
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2020 ◽
Vol 252
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pp. 117448
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