Editorial [Hot Topic: Model Organisms to Study Host - Pathogen Interaction: Prerequisites for the Identification of Novel Drug Targets (Guest Editor: Ludwig Eichinger)]

2011 ◽  
Vol 12 (7) ◽  
pp. 934-935 ◽  
Author(s):  
Ludwig Eichinger
Keyword(s):  
Guest Editor ◽  
Drug Targets ◽  
Topic Model ◽  
Model Organisms ◽  
Host Pathogen Interaction ◽  
Host Pathogen ◽  
Novel Drug ◽  
Novel Drug Targets

scholarly journals Identification of novel drug targets using model organisms

2009 ◽  
Vol 30 (2) ◽  
pp. 95
Author(s):  
Anthony Brzoska ◽  
Ryan Withers ◽  
Kylie Turner ◽  
Andrew Robinson ◽  
Nick Dizon ◽  
...  
Keyword(s):  
Drug Targets ◽  
Acquired Resistance ◽  
New Drugs ◽  
Model Organisms ◽  
Magic Bullet ◽  
The Public ◽  
Vancomycin Resistant ◽  
Novel Drug ◽  
General Community ◽  
Novel Drug Targets

Antibiotic resistance is an endemic problem within hospitals worldwide, and is becoming an increasing problem within the general community. Traditionally, physicians and the public have relied on the belief that as bacteria acquired resistance to one antibiotic, new drugs would be made available that could be used to combat those infections. The appearance of vancomycin-resistant Enterococcus (VRE) infections in the 1990s, combined with the withdrawal of funding for antimicrobial drug discovery and development by big Pharma, has led to the realisation that we can no longer assume that all infections can be treated with a ?magic bullet?. Recent years have seen the emergence of infections that are resistant to all clinically available antibiotics, including newly released drugs such as tigecycline. The cupboard is bare. Or at least it is heading that way.

Pathogen and Host-Pathogen Protein Interactions Provide a Key to Identify Novel Drug Targets

2021 ◽  
pp. 543-553 ◽  
Author(s):  
Shishir K. Gupta ◽  
Özge Osmanoglu ◽  
Mugdha Srivastava ◽  
Elena Bencúrová ◽  
Thomas Dandekar
Keyword(s):  
Protein Interactions ◽  
Drug Targets ◽  
Host Pathogen ◽  
Pathogen Protein ◽  
Novel Drug ◽  
Novel Drug Targets

Novel drug targets in 2019

2020 ◽  
Vol 19 (5) ◽  
pp. 300-300 ◽  
Author(s):  
Sorin Avram ◽  
Liliana Halip ◽  
Ramona Curpan ◽  
Tudor I. Oprea
Keyword(s):  
Drug Targets ◽  
Novel Drug ◽  
Novel Drug Targets

scholarly journals Identification of Polo-like kinases as potential novel drug targets for influenza A virus

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Marie O. Pohl ◽  
Jessica von Recum-Knepper ◽  
Ariel Rodriguez-Frandsen ◽  
Caroline Lanz ◽  
Emilio Yángüez ◽  
...  
Keyword(s):  
Influenza A Virus ◽  
Drug Targets ◽  
Influenza A ◽  
Novel Drug ◽  
Novel Drug Targets

scholarly journals Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures

10.3791/54738 ◽  
2016 ◽  
Author(s):  
Eamonn Morrison ◽  
Patty Wai ◽  
Andri Leonidou ◽  
Philip Bland ◽  
Saira Khalique ◽  
...  
Keyword(s):  
Functional Genomics ◽  
Cancer Cell ◽  
Drug Targets ◽  
Cell Spheroid ◽  
Novel Drug ◽  
Novel Drug Targets
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