Atheromatosis Extent in Coronary Artery Disease is not Correlated with Apolipoprotein-E Polymorphism and its Plasma Levels, but Associated with Cognitive Decline

2010 ◽  
Vol 999 (999) ◽  
pp. 1-8 ◽  
Author(s):  
Luciana Moreira Lima ◽  
Maria das Gracas Carvalho ◽  
Claudia Natalia Ferreira ◽  
Ana Paula Fernandes ◽  
Cirilo Pereira da Fonseca Neto ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Cognitive Decline ◽  
Apolipoprotein E ◽  
Plasma Levels ◽  
Apolipoprotein E Polymorphism ◽  
Artery Disease

scholarly journals Apolipoprotein E polymorphism is associated with both number of diseased vessels and extent of coronary artery disease in Czech patients with CAD

2012 ◽  
Vol 156 (2) ◽  
pp. 151-158 ◽  
Author(s):  
Jan Machal ◽  
Anna Vasku ◽  
Ota Hlinomaz ◽  
Petra Linhartova ◽  
Ladislav Groch ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Apolipoprotein E ◽  
Apolipoprotein E Polymorphism ◽  
Artery Disease

scholarly journals Relationship of apolipoprotein E polymorphism with lipid profiles in atherosclerotic coronary artery disease

2013 ◽  
Vol 65 (2) ◽  
pp. 71-78 ◽  
Author(s):  
Ibrahim Elmadbouh ◽  
Yasser Elghobashy ◽  
Eman Abd-Allah ◽  
Ahmad-Ashraf Reda ◽  
Adnan Fathe ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Apolipoprotein E ◽  
Lipid Profiles ◽  
Apolipoprotein E Polymorphism ◽  
Artery Disease ◽  
Relationship Of

Apolipoprotein E polymorphism as a risk factor for coronary artery disease

1999 ◽  
Vol 144 ◽  
pp. 71
Author(s):  
V. Spasojević-Kalimanovska ◽  
D. Kalimanovska-Oštrić ◽  
Z. Jelić-Ivanović ◽  
A. Topić
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Apolipoprotein E ◽  
Apolipoprotein E Polymorphism ◽  
Artery Disease

Association of Apolipoprotein E Polymorphism with Myocardial Infarction in Greek Patients with Coronary Artery Disease

2002 ◽  
Vol 18 (3) ◽  
pp. 118-124 ◽  
Author(s):  
Genovefa Kolovou ◽  
Nikos Yiannakouris ◽  
Marilena Hatzivassiliou ◽  
John Malakos ◽  
Deliana Daskalova ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Apolipoprotein E ◽  
Apolipoprotein E Polymorphism ◽  
Artery Disease

Relevance of Apolipoprotein E Polymorphism for Coronary Artery Disease in the Saudi Population

1999 ◽  
Vol 123 (12) ◽  
pp. 1241-1245
Author(s):  
Nduna Dzimiri ◽  
Brian F. Meyer ◽  
Syed S. Hussain ◽  
Chona Basco ◽  
Barima Afrane ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Apolipoprotein E ◽  
Elevated Serum ◽  
Serum Triglycerides ◽  
Increased Risk ◽  
Apolipoprotein E Polymorphism ◽  
Independent Risk Factors ◽  
Artery Disease

Abstract Background.—The apolipoprotein E alleles ε2 and ε4 have been reported as independent risk factors for coronary artery disease (CAD) and as predictors for the development of atherosclerosis. Methods and Results.—We determined by polymerase chain reaction the distribution of apolipoprotein E polymorphism in 320 Saudi blood donors (BD), 96 CAD patients, and 40 control subjects who had undergone angiography. Compared to controls, only ε4 was elevated in CAD patients. More than 61% (P < .0001) of the patients had angina, and 52.1% (P < .05) were diabetic; both of these factors were strongly associated with the presence of allele ε2. The ε2 allele was also associated with hypertension, elevated serum triglycerides, and total cholesterol. On the other hand, the allele ε4 appeared to be associated with increased risk of CAD and was also associated with hypertension, 3-vessel disease, and restenosis. Conclusions.—Accordingly, ε4 may be associated with increased risk of CAD, whereas ε2 appears to be a predictor of several risk factors for atherosclerosis.

Sign in / Sign up

Export Citation Format

Share Document