Immunotoxicity, Flow Cytometry, and Chemoinformatics: Review, Bibliometric Analysis, and New QSAR Model of Drug Effects Over Macrophages

2012 ◽  
Vol 12 (16) ◽  
pp. 1815-1833 ◽  
Author(s):  
Esvieta Tenorio-Borroto ◽  
Claudia G. Penuelas-Rivas ◽  
Juan C. Vasquez-Chagoyan ◽  
Francisco J. Prado-Pradoa ◽  
Xerardo Garcia-Mera ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Bibliometric Analysis ◽  
Drug Effects ◽  
Qsar Model

Immunotoxicity, Flow Cytometry, and Chemoinformatics: Review, Bibliometric Analysis, and New QSAR Model of Drug Effects Over Macrophages

2012 ◽  
Vol 12 (16) ◽  
pp. 1815-1833 ◽  
Author(s):  
Esvieta Tenorio-Borroto ◽  
Claudia G. Penuelas-Rivas ◽  
Juan C. Vasquez-Chagoyan ◽  
Francisco J. Prado-Pradoa ◽  
Xerardo Garcia-Mera ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Bibliometric Analysis ◽  
Drug Effects ◽  
Qsar Model

Flow cytometry: Potential utility in monitoring drug effects in breast cancer

1994 ◽  
Vol 32 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Steven K. Koester ◽  
Juhani U. Maenpaa ◽  
Valerie J. Wiebe ◽  
W. Jeffrey Baker ◽  
Gregory T. Wurz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Flow Cytometry ◽  
Drug Effects ◽  
Potential Utility ◽  
Monitoring Drug

scholarly journals Applications of flow cytometry on bacteria: Cell cycle kinetics, drug effects, and quantitation of antibody binding

Cytometry ◽  
2005 ◽  
Vol 2 (4) ◽  
pp. 249-257 ◽  
Author(s):  
Harald B. Steen ◽  
Erik Boye ◽  
Kirsten Skarstad ◽  
Barry Bloom ◽  
Tore Godal ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Flow Cytometry ◽  
Drug Effects ◽  
Antibody Binding ◽  
Cell Cycle Kinetics

Age Dependence of Murine Spermatogenesis

1995 ◽  
Vol 50 (3-4) ◽  
pp. 303-310 ◽  
Author(s):  
Ursula Beate Hacker-Klom
Keyword(s):  
Flow Cytometry ◽  
Drug Effects ◽  
Cell Types ◽  
Testis Weight ◽  
Age Dependence ◽  
Testicular Cell ◽  
Nmri Mice

The dependence of spermatogenesis function on murine age shall be investigated. Thus, testicular samples of at least 10 NMRI mice per group aged 0 to 26 months are analysed by flow cytometry after staining the DNA with DAPI. The aim of this study is to be able to account for the influence of age on mice. There are no changes in spermatogenesis in mice aged 11 weeks up to 16 months with respect to testis weight and to the frequency of different testicular cell types. From 16 months onwards, there is a tendency to a reduced spermatogenesis function; The frequency of round spermatids is decreased. In addition, there is an increased chromatin dispersion in elongated spermatids with age. Thus, older mice (>16 months) should not be used for experiments e.g. on radiation and drug effects any more. The frequency of abnormal diploid spermatozoa does not increase with age.

scholarly journals Drug effects in multiple rounds of cell division monitored by flow cytometry

2015 ◽  
Vol 12 (Suppl 1) ◽  
pp. O6
Author(s):  
Derek Davies
Keyword(s):  
Flow Cytometry ◽  
Cell Division ◽  
Drug Effects

Automation of cytokine flow cytometry assays

2004 ◽  
Vol 9 (1) ◽  
pp. 5-9 ◽  
Author(s):  
J DUNNE ◽  
H MAECKER
Keyword(s):  
Flow Cytometry ◽  
Cytokine Flow Cytometry

Reduction in Pain Sensitivity from Pharmacological Elevation of Blood Pressure in Persons with Chronically Low Blood Pressure

2009 ◽  
Vol 23 (3) ◽  
pp. 104-112 ◽  
Author(s):  
Stefan Duschek ◽  
Heike Heiss ◽  
Boriana Buechner ◽  
Rainer Schandry
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Pain Sensitivity ◽  
Pain Threshold ◽  
Pain Perception ◽  
Drug Effects ◽  
Pressure Effects ◽  
Double Blind ◽  
Low Blood Pressure ◽  
Present Trial

Recent studies have revealed evidence for increased pain sensitivity in individuals with chronically low blood pressure. The present trial explored whether pain sensitivity can be reduced by pharmacological elevation of blood pressure. Effects of the sympathomimetic midodrine on threshold and tolerance to heat pain were examined in 52 hypotensive persons (mean blood pressure 96/61 mmHg) based on a randomized, placebo-controlled, double-blind design. Heat stimuli were applied to the forearm via a contact thermode. Confounding of drug effects on pain perception with changes in skin temperature, temperature sensitivity, and mood were statistically controlled for. Compared to placebo, higher pain threshold and tolerance, increased blood pressure, as well as reduced heart rate were observed under the sympathomimetic condition. Increases in systolic blood pressure between points of measurement correlated positively with increases in pain threshold and tolerance, and decreases in heart rate were associated with increases in pain threshold. The findings underline the causal role of hypotension in the augmented pain sensitivity related to this condition. Pain reduction as a function of heart rate decrease suggests involvement of a baroreceptor-related mechanism in the pain attrition. The increased proneness of persons with chronic hypotension toward clinical pain is discussed.

Flow cytometry using the monoclonal antibody CD10-Pe/Cy5 is a useful tool to identify follicular lymphoma cells

2001 ◽  
Vol 66 (2) ◽  
pp. 100-106 ◽  
Author(s):  
M. Bellido ◽  
E. Rubiol ◽  
J. Ubeda ◽  
O. Lopez ◽  
C. Estivill ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Flow Cytometry ◽  
Follicular Lymphoma ◽  
Lymphoma Cells
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