scholarly journals The Managements and alternative therapies for comorbid sleep disorders in epilepsy

2020 ◽  
Vol 19 ◽  
Author(s):  
Weifeng Peng ◽  
Jing Ding ◽  
Xin Wang

Background: There is a complex and interactive relationship between sleep and epilepsy. Sleep disorders are common in patients with epilepsy, and methods for managing sleep disorders in patients with epilepsy are limited. Objective: This review is to address the relationships among sleep, sleep disorders, and epilepsy, focusing on the managements for sleep disorders in epilepsy, including some complementary and alternative therapies. Methods: The terms related to “sleep” and “epilepsy” were searched in “Pubmed” and “Cochrane Library”. Results: Sleep stages differently affects both of seizures and interictal epileptiform discharges. Seizures disrupt sleep architectures greatly, especially when arising from sleep in the night. Insomnia and obstructive sleep apnea (OSA) are the most frequent types of comorbid sleep disorders in patients with epilepsy. Pharmacological agents with both anti-convulsant and sedative effects are the priorities for comorbid sleep disorders in epilepsy. Continuous positive airway pressure (CPAP) therapy is the most effective non-pharmacological method to improve OSA and reduce seizures. Complementary and alternative therapies such as Chinese traditional medicine, cognitive behavioral therapy, meditation, yoga, neurofeedback, and acupuncture may have benefits on reducing seizures and improving sleep quality simultaneously by alleviating stress and seizure triggers, however, evidence-based therapies are still in deficiency. Conclusion: Managements for sleep disorders in patients with epilepsy are challenging. Large sample randomized controlled trials are in demand in the future.

2020 ◽  
Vol 27 (2) ◽  
pp. E202022
Author(s):  
Nurten Arslan Işık

Today, the treatment approaches recommended for smoking cessation are pharmacological and behavioral therapy. Both approaches are reported to be effective alone; however, when used together, the success rate increases. Modern medicine methods, however, often have a negative image due to cost, complexity and limitations in human life. For this reason, complementary and alternative therapies are widely used in the community for the treatment of many diseases in every age group. When people are asked why they prefer complementary and alternative therapies, the most important reason seems to be to improve quality of life by providing symptom control. Other reasons include economic problems, the lack of health insurance, the improvement of quality of life, the influence of the media and the environment, a strong belief that it will help, disappointment of conventional treatment failure, the noninvasiveness of most complementary and alternative therapies, fear of medical treatments, dissatisfaction with the current health system, medicines. Avoiding side effects can be called as a desire to have more control over health decisions. Contrary to many pharmacological and behavioral treatments that investigate the effectiveness of smoking cessation, only a few studies have included complementary and alternative treatments. Complementary treatment methods such as aromatherapy are thought to be regularly included in smoking cessation programs and their use should be ensured/expanded.


2021 ◽  
Author(s):  
Jing Pan ◽  
Shan Xiang ◽  
Shuangqian Dong ◽  
Xiuyun Qin ◽  
Jianwei Zhang

Abstract Background: With the increase in the incidence of Polycystic Ovary Syndrome (PCOS) over the years, restoring ovulation function has become one of the important contents of reproductive medicine research today. PCOS affects reproductive ability and harms physical and mental health. Studies show both complementary and alternative therapies to be effective in treating PCOS. However, the consistency of the conclusion is still inadequated. In view of this, we will develop a research to evaluate the effectiveness and safety of complementary and alternative therapies for PCOS. We therefore carry on a study protocol for a proposed network meta-analysis (NMA) and systematic review on PCOS.Methods: The following electronic bibliographic database will be searched: PubMed, Chinese National Knowledge Infrastructure (CNKI), VIP database, Wanfang database, The Cochrane Library, EMBASE and Web of Science from inception till 31 December2020. A search at the World Health Organization (WHO) International Clinical Trials Registry Platform will also be done. Two researchers will independently screen literature, extract data and assess the risk of bias of included studies. Analysis will be performed on included studies using the NMA technique. Data will be analyzed using ADDIS 1.16.8 and STATA 15.0.Results: This work will evaluate the safety and effectiveness of alternative and complementary therapies used in the treatment of PCOS.Conclusion: The results of this study will provide reliable evidence for clinicians in the field to build on for best practices in effective interventions (complementary and alternative therapies) for PCOS.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dania Jaber ◽  
Rafat Abu Ghannam ◽  
Waleed Rashed ◽  
Mohammad Shehadeh ◽  
Sa’ed H. Zyoud

Abstract Background Generally, complementary and alternative therapies (CAT) are accepted methods of treatment by patients with various types of conditions. Their use is becoming especially prevalent among patients with eye problems even in developed countries. Thus, we aimed to determine the pattern of use of CAT in this patient population, to identify the patient characteristics associated with the use of CAT, and to assess the types of CAT used. Methods A descriptive, cross-sectional study was conducted in Palestine at An-Najah National University Hospital between the time periods of October 2019 to May 2020, using questionnaire-based face to face interviews. Data were collected through convenience sampling. Patients responded to the questionnaire, which was focused on information adapted from previous research in this area, covering socio-demographic and clinical characteristics, types of CAT, source of information, and side effects on CAT use. Results A total of 86 patients were interviewed for our study. Over two thirds, 67% reported using CAT for the specific purpose of improving their eye condition, and about one third (29.1%) received more than one therapy. The most common therapies reported were duea’ (i.e. supplication) (47.1%) and herbal therapies (24.1%). It was shown that patients with bilateral involvement of their eyes were almost twice more likely to describe using CAT than patients with unilateral eye pathology (p = 0.006). Also, patients who underwent surgery as their route of treatment were significantly less likely to use CAT (p = 0.043). Most of our study participants mentioned a non-physician source as their source of information regarding CAT with family members being the most frequently mentioned (30.2%) followed by the internet (25.6%) and friends (19.8%). Conclusions The prevalence of CAT use among patients with eye disease is somewhat high in our study population. Because CAT may trigger adverse reactions, influence the progression of the disease, and interfere with conventional treatment, the ophthalmologist should frequently be asked patients with such diagnostics regarding the use of these therapies. Further work is required to analyze the mechanisms of action and to establish realistic guidelines for the use of these modalities.


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